Demystifying Strontium in AlgaeCal: Citrate vs. Ranelate
When evaluating the safety of strontium in AlgaeCal, it's crucial to first differentiate between the two primary forms of strontium: the natural form, strontium citrate, and the prescription drug, strontium ranelate. The confusion and associated risks often stem from the prescription version, leading to misconceptions about the mineral in general.
The Controversial Case of Strontium Ranelate
For years, strontium ranelate was used in some countries as a pharmaceutical treatment for osteoporosis. Studies found it could increase bone density and reduce fracture risk. However, this dual-action drug was later linked to serious side effects, including an increased risk of heart disease, blood clots, and other cardiovascular events, particularly in high-risk patients. As a result, its use has been restricted or discontinued in many regions, including the U.S., where it was never FDA-approved. The ranelate part of the compound is a synthetic molecule, and many of the adverse effects are attributed to this specific drug formulation.
Natural Strontium Citrate and AlgaeCal
AlgaeCal's strontium is sourced from mineralized red algae and is in the natural strontium citrate form. The company offers a separate product, Strontium Boost, containing 680 mg of strontium citrate per dose, which is designed to be taken in conjunction with the base AlgaeCal Plus supplement. Unlike ranelate, strontium citrate is available over the counter as a dietary supplement.
Clinical studies funded by AlgaeCal suggest that combining AlgaeCal Plus and Strontium Boost can significantly increase bone mineral density in postmenopausal women with no reported adverse side effects over a 7-year period. This safety profile is attributed to the product's natural sourcing and the specific citrate salt form, which is different from the ranelate drug.
Potential Safety Considerations for Strontium
While proponents emphasize the safety of the natural citrate form, there are some important considerations for certain individuals. Strontium is eliminated by the kidneys, so people with compromised kidney function are advised to exercise caution, as it could build up in their system. Health Canada also recommends a precautionary approach, advising those with heart or circulatory problems to avoid strontium supplements.
Furthermore, strontium competes with calcium for absorption in the gut. For this reason, supplements containing strontium citrate, like Strontium Boost, should be taken at least two hours away from calcium supplements or calcium-rich meals to ensure proper mineral uptake.
Comparison: Strontium Citrate vs. Strontium Ranelate
| Feature | Strontium Citrate (AlgaeCal) | Strontium Ranelate (Prescription Drug) |
|---|---|---|
| Formulation | Naturally derived from marine algae. | Synthetic compound bound with ranelic acid. |
| Source | Natural, food-based. | Pharmaceutical. |
| Availability | Over-the-counter dietary supplement. | Prescription-only in Europe and some regions; not available in the U.S.. |
| Typical Dosage | 680 mg of elemental strontium (Strontium Boost). | 2 grams per day. |
| Primary Safety Concerns | Caution advised for those with kidney or heart issues. | Increased risk of cardiovascular events, including heart attack and blood clots. |
| Regulatory Status | Regulated as a supplement in the U.S. and worldwide. | Restricted in Europe due to safety concerns; never FDA-approved. |
Factors to Consider Before Taking AlgaeCal with Strontium
- Kidney Function: If you have impaired kidney function, consult your healthcare provider, as strontium can accumulate in the body.
- Heart and Circulatory Health: Individuals with a history of heart disease, stroke, or blood clots should avoid strontium supplements due to potential risks, as recommended by health authorities.
- Timing of Doses: To maximize absorption, take strontium citrate supplements at least two hours apart from any calcium supplements or dairy products.
- Existing Medications: Strontium can interfere with the absorption of certain medications, such as some antibiotics. Always discuss supplementation with your doctor if you take other prescriptions.
- DXA Scan Results: Strontium's presence in bone can lead to an overestimation of bone mineral density (BMD) readings on dual-energy X-ray absorptiometry (DXA) scans. Your doctor should be aware of your supplementation to accurately interpret results.
Conclusion
For those wondering, 'Is strontium in AlgaeCal safe?', the answer is nuanced but generally positive when distinguishing the specific form. The natural strontium citrate used in AlgaeCal and Strontium Boost is clinically different from the synthetic, restricted prescription drug, strontium ranelate, which carries serious cardiovascular risks. While clinical studies supported by AlgaeCal have demonstrated safety and efficacy for bone density increases in certain populations, important precautions remain. Individuals with pre-existing heart conditions, circulatory problems, or kidney issues should avoid strontium supplements. For most healthy individuals seeking bone health support, the natural citrate form is considered safe when taken as directed and with a medical professional's guidance.
For more detailed clinical findings on strontium ranelate for comparison, you can review this PMC article from the National Institutes of Health.
