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Is tartaric acid safe for humans?

4 min read

Tartaric acid is naturally present in grapes and wine and is classified by the FDA as Generally Recognized as Safe (GRAS) for its common uses in food. However, this leads many to ask: is tartaric acid safe for humans, and are there limits to its safe use, especially in concentrated forms?

Quick Summary

Tartaric acid is safe for humans when consumed in small amounts typically found in food and wine. However, excessive intake, particularly of potassium-rich cream of tartar, can be dangerous and lead to hyperkalemia.

Key Points

  • Food Use is Safe: Tartaric acid is classified as 'Generally Recognized as Safe' (GRAS) by the FDA when used in food and beverages in normal, regulated amounts.

  • Dose-Dependent Risk: While safe in typical food quantities, large, concentrated doses can be toxic and cause serious health issues, including kidney damage and death.

  • Hyperkalemia Concern: Overdose of cream of tartar, a form of tartaric acid, is particularly dangerous due to its high potassium content, which can lead to life-threatening hyperkalemia.

  • Not for Infants: For safety reasons, tartaric acid is not permitted in food products specifically for infants and toddlers.

  • Topical Use Caution: When used in skincare, tartaric acid as an AHA can cause irritation at high concentrations and increases skin's sensitivity to the sun.

In This Article

What is Tartaric Acid?

Tartaric acid is a white, crystalline organic acid that occurs naturally in many plants, including grapes, tamarinds, and bananas. It is one of the primary acids found in wine and is a byproduct of the winemaking process. There are different forms, or isomers, of tartaric acid, but the L(+)-tartaric acid is the most common natural form and the one approved for use as a food additive.

Its properties as an antioxidant, acidity regulator, and flavor enhancer make it a valuable ingredient in both the food and cosmetic industries. In food, it is often added to candies, jams, jellies, and soft drinks to provide a distinct tart taste. As a salt, potassium bitartrate is more commonly known as cream of tartar, a substance used in baking and as a household cleaning agent.

Is Tartaric Acid Safe in Food?

For most people, consuming tartaric acid in the amounts typically found in processed foods and beverages is perfectly safe. Regulatory bodies worldwide, including the U.S. Food and Drug Administration (FDA), have evaluated its safety. The FDA classifies it as a "Generally Recognized as Safe" (GRAS) substance for its intended uses in food. The European Food Safety Authority (EFSA) also sets a high acceptable daily intake (ADI) for tartaric acid.

FDA and EFSA's Stance

The FDA has listed L(+)-tartaric acid as GRAS, allowing its use in food production under good manufacturing practices. The EFSA, following a re-evaluation, established a group ADI of 240 mg/kg of body weight per day for tartaric acid and its salts, a level that is unlikely to be exceeded through normal dietary exposure. In general, the amount of tartaric acid you would consume from a typical diet is well within the safe limits set by these organizations.

An important exception exists for young children. Tartaric acid is not permitted as an additive in food specifically for infants and toddlers due to potential developmental intolerance.

Potential Side Effects and Risks

While safe in food quantities, ingesting very large or concentrated amounts of tartaric acid can be harmful. The most significant risk comes from intentional misuse or accidental ingestion of concentrated forms, such as high doses of cream of tartar.

The Risk of Hyperkalemia

Cream of tartar (potassium bitartrate) is extremely high in potassium, with a single teaspoon containing a significant percentage of the daily recommended value. Consuming large amounts can lead to a dangerous condition called hyperkalemia, or excessive potassium levels in the blood. Symptoms of hyperkalemia include:

  • Abdominal discomfort and pain
  • Muscle weakness
  • Abnormal heart rhythms
  • Nausea and diarrhea

This risk is especially high for individuals with pre-existing kidney disease, as their kidneys may not be able to filter out the excess potassium efficiently.

Gastrointestinal and Kidney Issues

Overdosing on concentrated tartaric acid can also cause acute gastrointestinal irritation, leading to nausea, vomiting, and diarrhea. In severe cases, large doses have been linked to acute kidney injury and even death. This is not a risk associated with normal dietary intake but is a serious concern with misuse.

Uses of Tartaric Acid Beyond Food

Tartaric acid has diverse applications in other industries, including:

  • Skincare and Cosmetics: As an alpha-hydroxy acid (AHA), it's used in exfoliating products and serums to improve skin texture and reduce signs of aging. High concentrations can cause skin irritation, redness, and increase sun sensitivity. Proper use involves patch testing, starting with low concentrations, and using sun protection.
  • Pharmaceuticals: It is used as an excipient to improve the taste of oral medications and in the manufacture of effervescent salts.
  • Industrial Applications: Historically, it has been used in metal polishing, dyeing, and photography.

Comparative Safety of Food vs. Concentrated Tartaric Acid

Feature Tartaric Acid in Food Concentrated Tartaric Acid/Cream of Tartar
Usage Amount Small, regulated quantities Large, unregulated amounts
Regulatory Status Generally Recognized as Safe (GRAS) Not for unsupervised, large-quantity consumption
Safety for Humans Very high safety profile for most individuals High risk of toxicity and hyperkalemia
Key Component L(+)-Tartaric acid Potassium bitartrate (rich in potassium)
Common Effects Provides a tart flavor; generally no side effects Nausea, vomiting, abdominal pain, irregular heartbeat
Targeted Organs None in normal use Kidneys and cardiovascular system in overdose

How Much is Too Much?

For the average person, consuming the estimated lethal dose (LD50) of tartaric acid would require ingesting more than 500 grams (over a pound) at once, an amount far beyond normal dietary intake. The primary danger lies not in food consumption, but in the intentional or accidental swallowing of large, concentrated amounts, often from sources like cream of tartar. In such cases, the high concentration of potassium is the main concern.

Conclusion

In conclusion, the answer to the question "Is tartaric acid safe for humans?" is a resounding yes, provided it is consumed in the normal quantities found in food and beverages. It is a safe and regulated food additive (E334) with a long history of use. The danger arises exclusively from the misuse of concentrated forms, such as high-dose ingestion of cream of tartar, which poses a serious risk due to its high potassium content. It is essential for consumers to understand the distinction between normal food use and concentrated, supplemental ingestion to avoid adverse health outcomes. An excellent resource on the FDA's position on Generally Recognized as Safe substances, including tartaric acid, can be found here: FDA Guidance.

Frequently Asked Questions

Cream of tartar is a salt of tartaric acid, known chemically as potassium bitartrate. While tartaric acid is a naturally occurring organic acid, cream of tartar is a byproduct of winemaking and is used as a baking ingredient.

No, it is virtually impossible to consume a toxic amount of tartaric acid through normal dietary habits. The levels used in food processing are far below the hazardous threshold.

Symptoms of a severe overdose can include nausea, vomiting, abdominal pain, diarrhea, and potentially life-threatening hyperkalemia (high potassium levels) and kidney damage.

In large, concentrated doses, tartaric acid can be damaging to the kidneys. However, the small amounts found in food and wine pose no risk to healthy kidneys.

Tartaric acid is prohibited in food for very young children due to concerns about potential developmental intolerance and their immature metabolic systems.

Yes, but with caution. It is an effective AHA for exfoliation, but high concentrations can cause skin irritation, and it increases photosensitivity. Sunscreen use is a must when using such products.

The FDA officially recognizes tartaric acid as Generally Recognized As Safe (GRAS) for its intended use as a food additive, under specified conditions.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.