Skip to content

Is turkesterone natural? Understanding its plant-based origins

4 min read

In 2024, researchers studying the potential benefits of ecdysteroids, including turkesterone, reaffirmed that these compounds are naturally occurring in plants. While its name may sound synthetic, turkesterone is derived from botanical sources, but understanding its true nature requires a closer look at its origins and extraction process.

Quick Summary

Turkesterone is a naturally sourced phytoecdysteroid, primarily extracted from the Ajuga turkestanica plant native to Central Asia, functioning differently than synthetic anabolic steroids.

Key Points

  • Natural Origin: Turkesterone is a naturally occurring compound called a phytoecdysteroid, primarily extracted from the Ajuga turkestanica plant.

  • Non-Hormonal Action: Unlike synthetic anabolic steroids, turkesterone does not bind to androgen receptors and does not cause hormonal suppression.

  • Non-Banned Status: As of recent checks, turkesterone is not on the World Anti-Doping Agency's (WADA) prohibited list, making it permissible for competitive athletes in many sports.

  • High-Quality Sourcing is Key: The natural status of turkesterone in supplements depends on reputable sourcing and proper extraction, as imitation products exist.

  • Considered 'Natty': Many in the fitness community regard turkesterone as a 'natty' or natural supplement due to its plant-based origin and non-synthetic nature.

  • Benefits Beyond Muscle: Beyond its potential for muscle growth, turkesterone is also considered an adaptogen that may help the body cope with physical and mental stress.

In This Article

What Exactly Is Turkesterone?

Turkesterone is a type of phytoecdysteroid, which is a class of naturally occurring steroid hormones found in certain plants and insects. Specifically, the compound is primarily extracted from the Ajuga turkestanica plant, a flowering herb that is native to Central Asian regions, particularly Uzbekistan and Tajikistan. In its native regions, this plant has been used in traditional medicine for centuries to support vitality and recovery. The discovery and scientific study of turkesterone gained traction in the 1990s, when Uzbek scientists, building on earlier research, identified the high concentrations of these bioactive compounds in the plant.

The Role of Ecdysteroids in Nature

Ecdysteroids, as the name implies, are most famously known for their role in the molting and developmental processes of arthropods, like insects. The prefix 'phyto-' denotes that the compound is plant-derived. Plants produce these compounds as a defensive mechanism against herbivorous insects. In higher organisms, including humans, these plant-based steroids do not trigger the same hormonal pathways as traditional anabolic steroids, making them a natural alternative for those seeking performance-enhancing effects without hormonal disruption. This fundamental difference in how they work is a key part of the distinction between turkesterone and synthetic performance-enhancers.

The Extraction and Supplementation Process

For turkesterone to be used as a supplement, it must be extracted and concentrated from its plant sources. This process involves complex and often expensive methods to ensure a pure and potent final product.

Key Steps in Extraction

  • Harvesting: The Ajuga turkestanica plant is harvested, typically from high-altitude regions in Central Asia where it grows natively. Ethical and sustainable harvesting is important to preserve this resource.
  • Processing: The plant material, usually the roots or other parts rich in ecdysteroids, is processed to isolate the active compounds.
  • Extraction and Purification: Sophisticated techniques, like high-performance liquid chromatography (HPLC), are used to extract and purify turkesterone. The goal is to create a potent, standardized extract, often targeting a specific percentage of turkesterone content.
  • Supplement Creation: The purified extract is then encapsulated or processed into powders to create the final dietary supplement product.

The Importance of Sourcing and Quality

The market is not without its risks, and counterfeit products containing little to no actual turkesterone are not uncommon. Consumers must seek products from reputable manufacturers that provide third-party lab testing to verify the authenticity, purity, and concentration of their turkesterone extract. This is crucial because the quality can vary widely and affects both the efficacy and safety of the supplement.

Turkesterone vs. Anabolic Steroids: A Comparison

To fully understand why turkesterone is considered natural while other performance enhancers are not, it's essential to compare its characteristics with those of synthetic anabolic steroids.

Feature Turkesterone Anabolic Steroids
Source Plant-based extract (e.g., Ajuga turkestanica) Synthetically manufactured hormones
Mechanism Enhances protein synthesis via non-androgenic pathways (e.g., estrogen receptor beta and PI3K/Akt/mTOR) Binds to androgen receptors, mimicking testosterone
Hormonal Impact Does not alter natural testosterone or other hormone levels; no hormonal suppression Can significantly disrupt natural hormone levels, requiring Post-Cycle Therapy (PCT)
Side Effects Rare and mild (e.g., nausea on empty stomach) Significant risks, including liver damage, hormonal imbalances, gynecomastia, and hair loss
Legal Status Legal as a dietary supplement in most places; not on WADA's banned list, though monitoring is ongoing Controlled substances, illegal without a prescription in many countries

Status in Natural Athletics

In the fitness world, the term 'natty' refers to a person who builds their physique without using synthetic performance-enhancing drugs. Because turkesterone is a naturally derived plant extract and does not bind to androgen receptors or manipulate hormone levels, it is widely considered a 'natty' supplement by many in the community. Its legal status and non-hormonal action make it an appealing alternative for athletes who want to avoid the risks and legal issues associated with synthetic steroids. However, its effectiveness and safety are still areas of active research, and more human trials are needed to confirm the benefits widely reported anecdotally.

For a deeper look into the scientific research on ecdysteroids, you can review some of the latest findings via the National Institutes of Health.(https://pmc.ncbi.nlm.nih.gov/articles/PMC11085066/)

Conclusion

In summary, turkesterone is natural in origin, derived from plants like Ajuga turkestanica. As a phytoecdysteroid, it functions differently than synthetic anabolic steroids, offering potential muscle-building and performance benefits without impacting the endocrine system or requiring post-cycle therapy. Its status as a non-hormonal, non-banned substance makes it a popular choice for natural athletes. However, consumers should be diligent about verifying the source and purity of supplements to ensure they are getting a genuine product. While the anecdotal evidence is strong, ongoing research is key to fully understanding its potential and mechanism of action in humans. The quest for natural performance enhancement drives continued interest in turkesterone, and as long as sourcing is transparent, it remains a viable natural option for many.

Frequently Asked Questions

Turkesterone is an ecdysteroid, a class of steroid-like compounds found naturally in plants and insects, but it is not a synthetic anabolic steroid. It does not act on the body's androgen receptors and does not cause hormonal side effects associated with anabolic steroids.

No, turkesterone does not impact natural testosterone or other sex hormone levels. This is a major advantage over synthetic anabolic steroids and is why it does not require post-cycle therapy.

The primary natural source of turkesterone is the Ajuga turkestanica plant, a flowering species native to Central Asia, particularly Uzbekistan.

While other ecdysteroids can be found in small amounts in foods like spinach and quinoa, turkesterone itself is not typically abundant enough in foods to be a significant dietary source. Supplementation is required to consume it in meaningful quantities.

Based on current research and anecdotal evidence, turkesterone is generally considered safe when taken at recommended dosages. Common side effects are rare and mild, often related to digestive discomfort if taken on an empty stomach.

As of recent updates, turkesterone is not on the World Anti-Doping Agency's (WADA) prohibited list. However, some other ecdysteroids have been placed on WADA's monitoring list, so athletes should always stay informed of regulatory changes.

Turkesterone and creatine work through different mechanisms. Creatine increases ATP to improve strength, while turkesterone is believed to enhance protein synthesis. While creatine is more extensively researched, some people use both in combination.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.