The Digestive Process and Lactase
To understand how and why lactose intolerance can develop, it helps to first understand the role of lactase. Lactose, the main sugar in milk and dairy products, needs to be broken down into simpler sugars (glucose and galactose) for absorption. This crucial task is performed by the enzyme lactase, which is produced in the small intestine.
For humans and most mammals, lactase production is high during infancy, when milk is a primary food source. As children grow and their diets diversify, lactase production typically begins to decrease naturally—a process known as lactase nonpersistence. In some populations, a genetic mutation allows lactase production to continue into adulthood, but for the majority of the global population, this enzyme activity wanes.
The Natural Progression of Primary Lactose Intolerance
The most common reason for becoming lactose intolerant is this natural and genetic decline in lactase production over time. It is not a disease, but rather the body reverting to its natural ancestral state.
Causes related to primary intolerance:
- Genetic Predisposition: Your likelihood of experiencing this decline is heavily influenced by genetics. It's more common in people of East Asian, West African, Middle Eastern, and Southern European descent.
- Age-Dependent Decline: Symptoms of primary lactose intolerance may not manifest until later childhood, teenage years, or even adulthood, when lactase levels have dropped significantly. This can feel like a sudden change, but the reduction has been happening for years.
Secondary Lactose Intolerance: A Reversible Shift
Unlike the gradual, genetic form, secondary lactose intolerance can develop suddenly as a result of damage to the small intestine. This damage can temporarily reduce lactase production. For many, this is a reversible condition once the underlying cause is addressed.
Conditions that can trigger secondary intolerance include:
- Gastroenteritis: Acute infections can strip the intestinal lining of lactase for a short period.
- Celiac Disease: This autoimmune disease damages the small intestine and can impair lactase production. Following a gluten-free diet often resolves the lactose intolerance.
- Crohn's Disease: The inflammation associated with this inflammatory bowel disease can harm the lactase-producing cells.
- Chemotherapy and Antibiotics: Some treatments and medications can disrupt the gut lining.
- Surgery: Operations on the small intestine, such as a small bowel resection, can lead to temporary intolerance.
The Symptoms of Lactose Intolerance
Regardless of the cause, the mechanism for symptoms is the same. Without enough lactase, undigested lactose travels to the colon, where gut bacteria ferment it. This fermentation creates gases and pulls water into the colon, leading to the following symptoms:
- Abdominal bloating and cramps
- Diarrhea
- Excessive gas (flatulence)
- Nausea and stomach rumbling
Distinguishing Lactose Intolerance from Milk Allergy
It is vital to differentiate between lactose intolerance and a milk allergy, as they are different conditions with different causes and severity. While intolerance is a digestive issue, a milk allergy involves the immune system.
| Feature | Lactose Intolerance | Milk Allergy | 
|---|---|---|
| Cause | Lack of lactase enzyme to digest lactose sugar. | Immune system reaction to milk proteins (casein and whey). | 
| Onset | Usually develops after childhood (primary) or from gut damage (secondary). | Most common in infancy and childhood, though can occur at any age. | 
| Symptoms | Gastrointestinal: bloating, gas, diarrhea, cramps, nausea. | Immune response: hives, swelling, wheezing, vomiting, or anaphylaxis. | 
| Severity | Uncomfortable but generally not dangerous. | Potentially severe or life-threatening (anaphylaxis). | 
| Treatment | Limiting lactose, lactase enzyme supplements. | Complete avoidance of milk and milk protein. | 
How to Manage New-Found Lactose Intolerance
Discovering a new intolerance can be frustrating, but it is a very manageable condition. Many people don't need to eliminate all dairy. The severity of your symptoms depends on your residual lactase activity and the amount of lactose consumed.
Management strategies include:
- Modify Your Diet: Experiment with a two-week elimination diet to see if symptoms improve. You can then gradually reintroduce lactose-containing foods to determine your personal threshold.
- Choose Lower-Lactose Dairy: Aged, hard cheeses (like cheddar and parmesan) and yogurt with live active cultures are often better tolerated because their lactose content is significantly lower than milk.
- Use Lactase Supplements: Over-the-counter lactase enzyme tablets (e.g., Lactaid) can be taken before consuming dairy to help your body break down the lactose.
- Embrace Dairy Alternatives: The market offers a wide variety of lactose-free dairy products and plant-based milks (soy, almond, oat, coconut), yogurts, and cheeses.
- Pair Dairy with Meals: Eating dairy products alongside other foods can slow down digestion and make lactose easier for your body to process.
The Importance of Nutritional Balance
If you significantly reduce or eliminate dairy from your diet, it's crucial to ensure you get enough calcium and vitamin D from other sources.
Non-dairy sources of calcium:
- Fortified plant-based milks and juices
- Leafy greens like kale, spinach, and collard greens
- Tofu and fortified cereals
- Almonds and white beans
- Canned sardines and salmon with bones
Your healthcare provider may also recommend supplements for calcium and vitamin D to maintain bone health. A registered dietitian can help you build a balanced, lactose-intolerant-friendly diet.
Conclusion
Yes, you can become lactose intolerant even if you were previously able to digest dairy. For most adults, this is a natural, genetic process called primary lactose intolerance. For others, it is a temporary condition known as secondary lactose intolerance, brought on by an illness or gut injury. In either case, it is a highly manageable condition. With a better understanding of the cause, strategic dietary adjustments, and the use of supplements, those affected can effectively control their symptoms and maintain a healthy, balanced diet. For further information, consult the National Institute of Diabetes and Digestive and Kidney Diseases.