Determining Appropriate Ginkgo Consumption
Information regarding appropriate consumption amounts for Ginkgo biloba leaf extract should be discussed with a healthcare professional, as supplements are not regulated by the FDA. Clinical studies, however, offer insights into amounts that have been used. Research often utilizes daily amounts of standardized extract between 120 and 240 milligrams (mg). This is frequently divided into smaller portions throughout the day.
Standardized Extracts: Why They Matter
Choosing a high-quality, standardized extract is critical for both safety and consistency. The most researched form, known as EGb 761, is standardized to contain 24% flavone glycosides and 6% terpene lactones. Standardized products offer consistency in active compounds, reduce impurities like toxic ginkgolic acids, and provide a more reliable basis for expected effects and safety.
Potential Risks Associated with Higher Consumption
Consuming amounts exceeding those typically studied in research (often 240 mg daily) is sometimes associated with an increased likelihood of adverse effects. These can include headaches, dizziness, gastrointestinal issues, heart palpitations, increased bleeding risk, and seizures.
Important Safety Note: Raw ginkgo seeds are poisonous and should never be consumed, as they contain ginkgotoxin which can lead to seizures and even death.
Special Considerations and Medical Advice
Certain individuals should use caution or avoid ginkgo. This includes those on blood-thinning medications due to an increased risk of bleeding. Pregnant or breastfeeding women are generally advised against ginkgo due to insufficient safety data. Individuals with a history of seizures or diabetes should also be cautious, as ginkgo may increase seizure risk or interfere with blood sugar management.
| Comparison of Ginkgo Extract Consumption and Associated Effects | Typical Daily Amount (Standardized Extract) | Common Association | Potential Risks | General Approach |
|---|---|---|---|---|
| 120-240 mg | Cognitive function, peripheral arterial disease, tinnitus | Mild side effects are possible but uncommon. | Generally considered for most healthy adults; discuss with a healthcare professional to determine an appropriate starting amount. | |
| >240 mg | Amounts exceeding this range are not commonly recommended. | Higher risk of more serious side effects, including bleeding, seizures, and drug interactions. | Avoid amounts exceeding typical research levels unless under strict medical supervision. | |
| Raw/Roasted Seeds | Traditionally consumed in some cultures, but highly toxic. | Seizures and death reported; contains ginkgotoxin. | Absolutely avoid consumption of ginkgo seeds. |
Potential Drug Interactions
Discussing ginkgo use with a healthcare provider is essential, especially if taking other medications. Ginkgo can interact with various drugs, including anticoagulants, antiplatelets, antidepressants, anticonvulsants, diabetes medications, and NSAIDs, potentially increasing the risk of side effects like bleeding or affecting drug effectiveness.
Conclusion
For most healthy adults, standardized ginkgo extract amounts between 120 and 240 mg daily, potentially divided into smaller amounts, are generally well-tolerated and commonly used in research. Exceeding this range may increase risks. Always consult a healthcare professional before starting ginkgo, particularly if you have health conditions or take other medications.
For more information on supplement safety, see the National Center for Complementary and Integrative Health (NCCIH) website.
