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What are the negative effects of xanthan gum?

6 min read

According to the Food and Drug Administration (FDA), xanthan gum is a safe food additive for most people. However, consuming excessive amounts or having certain health conditions can lead to negative effects of xanthan gum, primarily digestive discomfort, and other risks for vulnerable populations.

Quick Summary

Xanthan gum is a common food additive that can cause digestive issues like bloating, gas, and diarrhea when consumed in large quantities. It also poses risks for premature infants and individuals with specific food allergies or medical conditions.

Key Points

  • Digestive Discomfort: High doses of xanthan gum can cause bloating, gas, abdominal pain, and diarrhea due to its soluble fiber content.

  • Risk for Infants: The use of xanthan gum in thickened formula for premature infants has been linked to severe, life-threatening intestinal problems.

  • Allergy Concerns: Individuals with severe allergies to corn, soy, or wheat should be cautious, as xanthan gum can be derived from these ingredients and may contain trace allergens.

  • Drug Interactions: Xanthan gum can lower blood sugar, which may interfere with diabetes medications; consult a doctor before increasing intake.

  • Inhalation Hazard: Handling large quantities of xanthan gum powder, such as in occupational settings, can cause respiratory irritation and flu-like symptoms.

  • GI Sensitivity: People with conditions like IBS or IBD may find that xanthan gum exacerbates their digestive symptoms even at lower intake levels.

In This Article

Understanding Xanthan Gum

Xanthan gum is a polysaccharide, or a chain of sugar molecules, created by fermenting a simple sugar with the Xanthomonas campestris bacterium. The resulting goo is dried and ground into a powder, which acts as a powerful thickening, stabilizing, and emulsifying agent when added to liquid. It is widely used in processed foods, including salad dressings, sauces, gluten-free baked goods, and dairy-free alternatives, to improve texture and prevent separation. Beyond the food industry, it is also found in cosmetics, personal care products like toothpaste, and certain medications.

Because xanthan gum is a soluble fiber, the human body cannot digest or absorb it. For this reason, it adds no nutritional value and passes through the digestive system largely intact. However, this very property is what leads to the most common adverse effects when consumed in larger quantities.

The Digestive Toll of Excessive Xanthan Gum

When xanthan gum, or any soluble fiber, is consumed in excess, it absorbs a large amount of water and swells in the intestines. This creates a gel-like substance that can have a pronounced laxative effect and cause significant gastrointestinal discomfort. While the small amounts typically found in food are unlikely to cause problems for most people, intake from supplements or multiple processed foods can accumulate and lead to issues.

List of Common Digestive Side Effects:

  • Bloating and gas: As the gum ferments in the large intestine, it can produce gas, leading to uncomfortable bloating and abdominal distension.
  • Diarrhea and softer stools: The bulking and water-retaining properties of xanthan gum can stimulate bowel movements and lead to loose or softer stools.
  • Abdominal pain: Increased intestinal activity and gas can sometimes result in cramping and stomach pain.
  • Altered gut bacteria: Studies in controlled settings have shown that high doses can alter the gut microbiome. While this can sometimes be beneficial, the long-term effects are still under investigation and may not be desirable for all individuals.

Specific Health and Allergic Concerns

While the average consumer is unlikely to experience severe side effects, certain individuals and populations are at a higher risk and should exercise caution.

At-Risk Groups:

  • People with severe allergies: The sugar substrate used to create xanthan gum can be derived from common allergens like corn, wheat, soy, or dairy. Though the final product is highly processed, trace amounts of these allergens may remain, posing a risk to those with severe sensitivities. Always check the manufacturer's sourcing if you have a serious allergy.
  • Premature infants: Xanthan gum used as a thickener in infant formula has been linked to severe intestinal inflammation and necrotizing enterocolitis (NEC), a life-threatening condition, in premature infants. For this reason, its use is not recommended for this vulnerable group.
  • Individuals with gastrointestinal conditions: People with irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD) may be more sensitive to the fermentable fiber in xanthan gum and should limit or avoid it to prevent triggering symptoms.
  • Those on specific medications: Because xanthan gum can slow the absorption of sugar, individuals on diabetes medication should be cautious as it could affect blood sugar control. They should consult a doctor before significantly increasing their intake.

Inhalation and Powder Exposure

Another significant health risk is related to the inhalation of xanthan gum powder, which primarily affects workers in food processing or industrial settings. Airborne particles can cause respiratory irritation and flu-like symptoms. This is not a concern for home cooks using small amounts but highlights the potential for irritation from concentrated, prolonged exposure.

Comparison: Effects of Normal vs. Excessive Intake

Feature Normal Dietary Intake (Small Amounts) High or Supplemental Intake (Excessive)
Intake Level Typically less than 1 gram per day. 15 grams or more per day.
Safety Profile Considered safe for most people by regulatory bodies like the FDA. High doses can lead to adverse effects, especially in sensitive individuals.
Digestive Impact Minimal to no digestive effect, though it can help regularity. Increased gas, bloating, diarrhea, and abdominal pain.
Allergy Risk Low, but possible for those with severe sensitivities to source materials (e.g., corn, soy). Same risk profile, but potential for greater or more frequent exposure.
Targeted Populations Generally safe for the general population. Should be limited or avoided by infants, diabetics, and those with GI issues.

Conclusion

While widely regarded as safe for consumption in the small quantities typically found in packaged foods, the negative effects of xanthan gum are most pronounced with high intake. The primary concerns revolve around its potent digestive impact when consumed in large doses, leading to symptoms like bloating, gas, and a laxative effect. Furthermore, specific health risks exist for premature infants, individuals with severe allergies to source materials, and those with pre-existing gastrointestinal conditions. Consumers should be aware of their personal tolerance and consider their total daily intake from various sources. For the average person, xanthan gum in moderation poses little threat, but those with sensitivities or specific medical concerns should proceed with caution and consult a healthcare professional. For more in-depth nutritional information, visit the National Institutes of Health.

Understanding the Risks of Xanthan Gum

  • High-dose digestive issues: Excessive intake can cause bloating, gas, and abdominal pain due to its bulk-forming, soluble fiber properties.
  • Severe infant complications: Thickened formulas containing xanthan gum have been linked to dangerous gastrointestinal issues in premature infants.
  • Allergen cross-contamination: Individuals with severe allergies to corn, wheat, or soy must verify the gum's source, as trace amounts of allergens can remain from the fermentation process.
  • Potential for anaphylaxis: Though rare, some individuals with sensitivities have reported serious allergic reactions, including life-threatening anaphylaxis.
  • Drug interactions: The blood sugar-lowering effect of xanthan gum can be problematic for people taking certain diabetes medications.
  • Gastrointestinal condition flare-ups: People with IBS or IBD may experience exacerbated symptoms from xanthan gum's effects on the digestive tract.
  • Inhalation hazards: Handling large quantities of xanthan gum powder can cause respiratory irritation and flu-like symptoms, posing an occupational hazard.

FAQs

Q: Is xanthan gum safe to eat? A: For most people, xanthan gum is safe to eat in the small amounts found in processed foods. The FDA considers it safe, and adverse effects are typically only seen with high intake, such as from supplements.

Q: Can xanthan gum cause gas and bloating? A: Yes, consuming high quantities of xanthan gum can lead to increased gas and bloating. This is because it is a soluble fiber that ferments in the gut, which can produce gas.

Q: Why is xanthan gum bad for premature infants? A: In premature infants, xanthan gum has been linked to a life-threatening intestinal condition called necrotizing enterocolitis (NEC). This is because their digestive systems are not yet developed enough to handle the thickener safely.

Q: What is a safe daily amount of xanthan gum? A: The typical daily intake from food is less than 1 gram and poses no safety concern. Doses up to 15 grams per day have been studied in supplements and can cause digestive issues, but are generally considered safe for healthy adults.

Q: Should I avoid xanthan gum if I have a soy or corn allergy? A: You should be cautious and check the manufacturer's sourcing. Xanthan gum is made by fermenting sugar that can come from sources like corn or soy, and trace allergens might remain.

Q: Does xanthan gum have a laxative effect? A: Yes, at higher doses, xanthan gum can act as a bulk-forming laxative by drawing water into the intestines, softening stools and increasing bowel movement frequency.

Q: Are there any alternatives to xanthan gum? A: Yes, alternatives include guar gum, psyllium husk, cornstarch, and flaxseed. These can be used for thickening and binding in recipes and may be better tolerated by some individuals.

Frequently Asked Questions

For most people, xanthan gum is safe to eat in the small amounts found in processed foods. The FDA considers it safe, and adverse effects are typically only seen with high intake, such as from supplements.

Yes, consuming high quantities of xanthan gum can lead to increased gas and bloating. This is because it is a soluble fiber that ferments in the gut, which can produce gas.

In premature infants, xanthan gum has been linked to a life-threatening intestinal condition called necrotizing enterocolitis (NEC). This is because their digestive systems are not yet developed enough to handle the thickener safely.

The typical daily intake from food is less than 1 gram and poses no safety concern. Doses up to 15 grams per day have been studied in supplements and can cause digestive issues, but are generally considered safe for healthy adults.

You should be cautious and check the manufacturer's sourcing. Xanthan gum is made by fermenting sugar that can come from sources like corn or soy, and trace allergens might remain.

Yes, at higher doses, xanthan gum can act as a bulk-forming laxative by drawing water into the intestines, softening stools and increasing bowel movement frequency.

Yes, alternatives include guar gum, psyllium husk, cornstarch, and flaxseed. These can be used for thickening and binding in recipes and may be better tolerated by some individuals.

Workers exposed to xanthan gum powder have reported respiratory irritation, flu-like symptoms, and nose and throat irritation due to inhalation.

Some animal studies have suggested a potential for pro-inflammatory responses, but more human research is needed to determine if this occurs and to what extent.

There is limited data on the effects of xanthan gum during pregnancy and breastfeeding. It is best to stick to amounts normally found in food and consult a healthcare provider for larger amounts.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.