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What are the negative side effects of tart cherries?

4 min read

According to the National Institutes of Health, cherries, including the tart variety, are a healthy source of antioxidants and fiber. However, consuming large quantities of tart cherries, especially in concentrated forms, can cause negative side effects, including gastrointestinal distress and drug interactions.

Quick Summary

Tart cherries, particularly in concentrated forms, can cause adverse effects like digestive upset due to sorbitol content and may trigger allergic reactions. Certain health conditions and medications can increase risks, so caution is advised when supplementing.

Key Points

  • Gastrointestinal Upset: Excessive tart cherry consumption, especially concentrated juice, can cause bloating, gas, and diarrhea due to high levels of sorbitol.

  • Drug Interactions: Tart cherry products can interact with blood thinners (like warfarin), blood pressure medications (ACE inhibitors), and others, so consult a doctor if you are on prescription medication.

  • Allergic Reactions: Some individuals, particularly those with birch pollen allergies, may experience Oral Allergy Syndrome (OAS) from raw cherries, causing oral itching and swelling.

  • Kidney Concerns: Those with kidney disease should be cautious, as tart cherry products can increase potassium levels and, in rare cases, have been linked to acute kidney injury.

  • Blood Sugar Impacts: Diabetics need to monitor their intake of tart cherry juice, as the sugar content, particularly in sweetened versions, can affect blood sugar levels.

  • Potential Weight Gain: Consuming too much high-calorie tart cherry juice, especially with added sugars, can contribute to weight gain over time.

In This Article

Gastrointestinal Issues from High Sorbitol

Excessive consumption of tart cherries, particularly concentrated juice, can lead to significant gastrointestinal issues for many people. The primary culprit is sorbitol, a sugar alcohol found naturally in cherries and many other fruits. Sorbitol is poorly absorbed by the small intestine and, when consumed in high amounts, can draw water into the colon, leading to bloating, gas, stomach pain, and diarrhea. This effect is more pronounced in individuals with irritable bowel syndrome (IBS) or general fructose malabsorption issues. Unlike eating a small serving of whole, fresh fruit, consuming concentrated juice means ingesting a significantly higher dose of sorbitol, which can overwhelm the digestive system.

Allergic Reactions and Oral Allergy Syndrome

While relatively rare, some individuals may experience allergic reactions to tart cherries. This can be a primary allergy to the fruit itself, but it is more commonly a secondary allergy linked to Oral Allergy Syndrome (OAS). OAS occurs when the immune system mistakes the proteins in certain raw fruits, like cherries, for those in common tree pollens, such as birch. Symptoms of OAS typically manifest as itching or tingling in the mouth, lips, and throat and usually subside quickly. More severe reactions, though uncommon, can include hives, swelling, and in very rare cases, anaphylaxis. For those with a known pollen allergy, especially to birch, it is wise to be cautious with raw cherries. Cooking the cherries often breaks down the allergenic proteins, making them safer to consume for those with OAS.

Drug Interactions and Contraindications

Tart cherries contain compounds, such as salicylates and flavonoids, that can interact with certain medications. It is crucial to consult a healthcare provider before adding tart cherry products to your routine, especially if you are on prescription drugs.

  • Blood Thinners: Tart cherry products, particularly supplements, have been shown to have a mild blood-thinning effect. This can pose a risk for individuals taking anticoagulant medications like warfarin, potentially increasing the risk of bleeding.
  • Blood Pressure Medications: Some evidence suggests tart cherries can affect blood pressure, and they may interact with medications like ACE inhibitors (e.g., lisinopril) and beta-blockers (e.g., carvedilol), though the interaction data is not robust.
  • Other Medications: Interactions with antibiotics and corticosteroids have also been cited, though more research is needed.

Risks for Specific Health Conditions

Certain health conditions can be worsened by tart cherry consumption, especially in concentrated forms. Moderation is key, and medical supervision is recommended.

  • Kidney Disease: Tart cherry juice can be high in potassium, which can be problematic for older adults or individuals with chronic kidney disease (CKD) whose kidneys are less efficient at filtering out excess nutrients. A case report also detailed an instance of acute kidney injury caused by concentrated cherry products in a patient with CKD, possibly due to the anti-inflammatory compounds affecting kidney function.
  • Diabetes: While tart cherries are generally low on the glycemic index, concentrated juice or sweetened varieties contain significant amounts of natural and potentially added sugars. This can negatively impact blood sugar levels for individuals with diabetes, requiring careful monitoring.
  • Pregnancy and Lactation: The safety of tart cherry supplements during pregnancy and breastfeeding is not well-documented. To be cautious, medical professionals advise limiting consumption to food amounts rather than concentrated supplements during these periods.

Potential for Weight Gain

While a glass of tart cherry juice may seem healthy, consuming too much can lead to unintended weight gain. Many commercial juices are high in both natural and added sugars, increasing the caloric content. When juice is consumed in excess, these extra calories can contribute to weight gain over time. Opting for whole fruit instead of juice or concentrate can mitigate this risk, as the fiber in the fruit helps slow sugar absorption and promotes a feeling of fullness.

Comparison of Tart Cherry Forms

Feature Whole Tart Cherries Tart Cherry Juice Tart Cherry Concentrate
Sorbitol Content Lower per serving due to fiber High, can cause digestive issues Very high, highest risk for digestive upset
Sugar Content Moderate, tempered by fiber High, especially if sweetened Very high, most concentrated sugar source
Fiber High, beneficial for digestion None None
Caloric Density Lower per serving Higher Highest
Drug Interaction Risk Low, standard food quantity Moderate, due to concentration High, highest concentration of active compounds

Managing Your Intake

If you choose to incorporate tart cherries into your diet, consider these strategies to minimize the risk of side effects:

  • Start with Small Servings: Introduce tart cherry products slowly and in small doses to assess your body's tolerance, particularly if you have a sensitive stomach.
  • Opt for Whole Fruit: Whenever possible, choose whole, fresh, or frozen tart cherries over juice or supplements. The fiber content in the whole fruit helps buffer the impact of its natural sugars and sorbitol on your digestive system.
  • Read Labels Carefully: When buying tart cherry juice or concentrate, check the nutrition label for added sugars and total carbohydrate content. Choose unsweetened varieties whenever possible.
  • Stay Hydrated: Drinking plenty of water can help alleviate some of the digestive discomfort caused by sorbitol.
  • Consult Your Doctor: Especially if you have a pre-existing medical condition like diabetes or kidney disease, or if you are on medications, speak with a healthcare provider before starting a tart cherry regimen.

Conclusion

While celebrated for their health benefits, tart cherries are not without potential negative side effects. The risk of digestive problems due to high sorbitol content, allergic reactions, and concerning interactions with certain medications are real considerations. Individuals with pre-existing conditions like kidney disease and diabetes must be particularly cautious with concentrated forms, which can exacerbate health issues. By being mindful of serving sizes, choosing whole fruit over concentrated juice, and consulting with a healthcare professional, consumers can make informed choices to enjoy the benefits while mitigating the risks associated with tart cherries. For more detailed medical advice, always seek guidance from a qualified health practitioner. WebMD.com is one of many trusted resources to consult.

Frequently Asked Questions

Yes, tart cherry juice can cause diarrhea, especially when consumed in large quantities. This is primarily due to its high concentration of sorbitol, a sugar alcohol that can have a laxative effect.

For individuals with healthy kidneys, tart cherries are generally safe. However, those with chronic kidney disease (CKD) should be cautious due to the potential for high potassium levels in juice. There have been case reports linking high concentrate consumption to acute kidney injury in CKD patients.

Yes, tart cherry products can have a mild blood-thinning effect and may interact with anticoagulant medications like warfarin. If you are on a blood thinner, you must consult your doctor before using tart cherry supplements or concentrated products.

Yes, while a primary allergy to cherries is rare, it is possible. More commonly, individuals with birch pollen allergies may develop a secondary allergy known as Oral Allergy Syndrome (OAS), which causes mild oral symptoms from raw cherries.

Diabetics should be cautious with tart cherry juice, especially sweetened or concentrated varieties. While tart cherries have a low glycemic index, the high sugar content in juices can impact blood sugar levels, so medical consultation is recommended.

Yes, excess consumption of tart cherry juice, especially varieties with added sugar, can lead to weight gain. Juice lacks the fiber of whole fruit, making it easier to consume extra calories that contribute to weight gain.

The best way to consume tart cherries is as whole, fresh fruit in moderation. This provides fiber that moderates the absorption of natural sugars and sorbitol, reducing the risk of digestive issues.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.