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What are the potential side effects of goji berries?

4 min read

Though lauded as a superfood for millennia, goji berries are not without their risks; reports show that the potential side effects of goji berries can range from mild digestive upset to serious medication interactions. Historically used in Traditional Chinese Medicine, their increasing popularity in the West has brought greater scrutiny to their safety profile, especially for those with pre-existing health conditions.

Quick Summary

Goji berries can cause digestive issues, allergic reactions, and interact dangerously with certain medications like blood thinners and diabetes drugs. Pregnant women should exercise caution due to a compound that may induce uterine contractions.

Key Points

  • Drug Interactions: Goji berries can dangerously interact with medications like blood thinners (warfarin), diabetes, and high blood pressure drugs.

  • Pregnancy Risk: Due to the compound betaine, goji berries are potentially unsafe during pregnancy as they may induce uterine contractions.

  • Allergy Warning: As part of the nightshade family, goji berries can cause allergic reactions, especially in those with sensitivities to related foods.

  • Digestive Upset: The high fiber content can cause bloating, gas, or diarrhea if consumed in large quantities, especially when first introduced to the diet.

  • Overconsumption Dangers: Extremely high intake may lead to rare but serious side effects like toxic hepatitis, as seen in isolated case reports.

  • Moderation is Key: For most healthy adults, consuming goji berries in small to moderate amounts (around 10-20g daily) is considered safe.

In This Article

Common Digestive Issues

For many people, the most likely side effect of consuming goji berries comes from their high fiber content. While fiber is beneficial for digestive health, a sudden increase in intake can overwhelm the system, especially for those not accustomed to a high-fiber diet.

Symptoms of Digestive Discomfort

  • Bloating and gas: A rapid increase in fiber intake can cause gas and bloating as the gut bacteria work to break it down.
  • Stomach cramps: Some individuals may experience mild abdominal pain or discomfort when first introducing goji berries to their diet.
  • Diarrhea: Overconsumption can lead to loose stools or diarrhea.

To mitigate these effects, it is best to start with a small serving of goji berries and gradually increase the amount over time. This allows your digestive system to adapt to the added fiber.

Dangerous Drug Interactions

One of the most critical safety concerns regarding goji berries is their potential to interact with certain prescription medications. If you are taking any of the following drugs, it is essential to consult a healthcare professional before consuming goji berries.

Warfarin (Blood Thinners)

Several case reports have documented that goji berries can significantly increase the risk of bleeding in individuals taking warfarin, a common blood-thinning medication. The berries may enhance warfarin's effects, potentially leading to a higher International Normalized Ratio (INR), a measure of blood clotting time, and an increased risk of bruising or bleeding.

Diabetes Medications

Goji berries have a demonstrated effect on lowering blood sugar levels. While this is beneficial for some, it can be dangerous for individuals with diabetes who are already taking medication to control their blood sugar. The combination can lead to hypoglycemia, a condition where blood sugar levels drop too low.

High Blood Pressure Medications

Similar to diabetes drugs, goji berries can lower blood pressure. If you are already on antihypertensive drugs, consuming goji berries could cause your blood pressure to drop excessively, leading to dizziness or other complications.

Allergic Reactions and Nightshade Sensitivity

As a member of the nightshade family (Solanaceae), which also includes tomatoes, potatoes, and peppers, goji berries can trigger allergic reactions in sensitive individuals.

Symptoms of an Allergic Reaction

  • Skin reactions: Hives, rashes, and itchiness are common allergic symptoms.
  • Gastrointestinal distress: Nausea, vomiting, and abdominal cramps can occur.
  • Respiratory issues: In severe cases, wheezing or difficulty breathing can manifest.

Allergies to goji berries have been linked to cross-reactivity with other foods and plants. Individuals with known allergies to peaches, tomatoes, tobacco, or nuts may have a higher risk.

Risks During Pregnancy and Breastfeeding

The consumption of goji berries during pregnancy is often advised against due to safety concerns. The berries contain a compound called betaine, which, in excess, has been associated with uterine contractions in early pregnancy and an increased risk of miscarriage or preterm labor. Although some traditional uses exist, modern medical advice is to err on the side of caution and avoid them during this sensitive period. There is also insufficient data on the safety of goji berries during breastfeeding, so it is best to avoid them.

Goji Berry vs. Common Superfoods: A Side Effect Comparison

Feature Goji Berries Blueberries Raspberries
Drug Interactions Significant risk with warfarin, diabetes, and blood pressure meds. Generally low risk. Generally low risk.
Allergy Risk Possible, especially for those with nightshade sensitivity. Rare, though possible. Rare, though possible.
Pregnancy Risk Potential for uterine contractions; not recommended. Considered safe in moderation. Considered safe in moderation.
Common Digestive Side Effects Bloating, gas, diarrhea if over-consumed. Mild, if any, with typical consumption. Mild, if any, with typical consumption.

Risk of Overconsumption

While moderate intake of goji berries is generally safe for most healthy adults, consuming excessive amounts can lead to other complications. In a rare case, one individual who consumed goji berry tea frequently developed toxic hepatitis, though this is not a widespread risk. Overloading on certain nutrients, such as potassium, can also cause issues. Adhering to recommended serving sizes, typically around 10–20 grams of dried berries per day, is crucial for safety. If you have pre-existing liver issues, it is particularly important to be mindful of your intake.

How to Safely Consume Goji Berries

For most healthy individuals, a moderate serving of goji berries can be a nutritious addition to the diet. To minimize risk, consider these tips:

  • Start small: Begin with a very small serving to see how your body reacts before increasing the amount.
  • Buy from reputable sources: Adulterated or low-quality products can pose risks. Purchase goji berries from trusted suppliers to ensure quality.
  • Avoid during illness: Some traditional Chinese medicine practitioners recommend avoiding goji berries during infections, colds, or diarrhea.
  • Heed warnings: If you fall into any of the high-risk categories (on specific medication, pregnant, breastfeeding), it is safest to avoid goji berries entirely or to discuss it with a healthcare professional.

Conclusion

Goji berries offer a range of potential health benefits, but they also carry important risks that should not be overlooked. From digestive issues caused by high fiber to potentially life-threatening interactions with common medications like warfarin, a cautious approach is warranted. For most healthy individuals, moderation is key, and understanding your personal health profile is essential before making them a regular part of your diet. Those with specific health conditions, allergies, or who are pregnant should always consult a doctor. By staying informed and practicing careful consumption, you can enjoy goji berries while minimizing potential harm.

For more general information on dietary supplements and their regulation, the U.S. Food and Drug Administration (FDA) provides helpful resources.

Always Consult a Healthcare Provider

This information is for informational purposes only and does not constitute medical advice. For a personalized assessment, consult with a qualified healthcare professional. Do not start, stop, or change any medication or treatment without your doctor's guidance.

Frequently Asked Questions

No, it is highly recommended to avoid goji berries if you are on blood-thinning medications like warfarin. Goji berries can increase the medication's effect and raise the risk of bleeding.

It is not recommended to consume goji berries while pregnant. The berries contain betaine, which has been linked to uterine contractions and a potential risk of miscarriage.

Bloating can occur due to the high fiber content in goji berries, particularly if you are not used to a high-fiber diet. Increasing your intake gradually can help prevent digestive upset.

Yes, some individuals may experience an allergic reaction, especially if they are sensitive to other nightshade plants or foods like peaches, tomatoes, or nuts.

Excessive consumption can lead to digestive issues like gas and diarrhea due to high fiber intake. In rare cases, high doses have been linked to toxic hepatitis.

Yes, goji berries can lower blood pressure. Taking them alongside blood pressure medication may cause your blood pressure to drop too low.

The safety of goji berry supplements can vary due to inconsistent quality control. It's often safer to consume whole foods, and you should always choose reputable brands and consult a doctor.

Dried goji berries are generally safe for most healthy adults to eat in moderation. The same precautions regarding drug interactions, allergies, and overconsumption still apply.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.