Skip to content

What are the side effects of Camellia sinensis?

5 min read

According to research, moderate consumption of tea, derived from the Camellia sinensis plant, is considered safe for most people, but higher doses or concentrated extracts can lead to side effects. Understanding what are the side effects of Camellia sinensis is crucial for safe consumption, especially for individuals with underlying health conditions or sensitivities to caffeine.

Quick Summary

The side effects of Camellia sinensis primarily stem from its caffeine and tannin content, causing mild issues like anxiety, headaches, and digestive upset. Rare but more severe risks include liver toxicity with high-dose extracts and negative interactions with certain medications. Intake amount and individual sensitivity play key roles in determining the likelihood and severity of adverse reactions.

Key Points

  • Caffeine-Related Problems: High intake of Camellia sinensis can cause anxiety, jitteriness, and insomnia, particularly in caffeine-sensitive individuals.

  • Digestive Upset: The tannins in tea can increase stomach acid, leading to nausea, heartburn, or diarrhea, especially when consumed on an empty stomach.

  • Rare Liver Toxicity: Although very rare, concentrated extracts of Camellia sinensis have been linked to liver damage in some cases.

  • Impaired Nutrient Absorption: Tea can inhibit the absorption of iron and calcium, which is a concern for individuals with deficiencies or conditions like osteoporosis.

  • Serious Drug Interactions: Camellia sinensis can negatively interact with blood thinners, certain heart medications, and stimulants, among others.

  • Safe Consumption: To minimize risks, consume brewed tea in moderation, avoid high-dose extracts, and drink with or after a meal.

In This Article

Understanding the Origins of Camellia sinensis

Camellia sinensis is the plant species from which all true teas—green, black, white, and oolong—are derived. The processing method determines the final tea type and influences the concentration of compounds like caffeine and catechins. While celebrated for its antioxidant properties and health benefits, consumers must be aware of the potential negative reactions, which vary depending on the type of tea and method of consumption. Most side effects are linked to high intake, but sensitive individuals may experience issues even with moderate amounts.

Common Side Effects from Caffeine and Tannins

Most of the reported adverse effects associated with Camellia sinensis are due to its two primary components: caffeine and tannins. The amount of caffeine varies depending on the tea type, with green tea typically having a moderate level, but supplements can contain much higher, concentrated doses.

Caffeine-related side effects

For those sensitive to caffeine or consuming large quantities, several side effects can occur:

  • Nervousness and Jitteriness: Caffeine stimulates the central nervous system, which can cause feelings of anxiety, restlessness, and jitteriness.
  • Insomnia and Sleep Disruption: As a stimulant, caffeine can interfere with sleep patterns, especially when consumed later in the day.
  • Headaches: Certain individuals, particularly those prone to migraines, may experience headaches due to caffeine.
  • Increased Heart Rate and Irregular Heartbeat: High caffeine intake can increase heart rate and, in rare cases, cause heart palpitations or an irregular heartbeat.

Digestive system issues

Tea contains tannins, compounds that give tea its astringent flavor but can irritate the stomach lining. This is more likely to occur when tea is consumed on an empty stomach.

  • Stomach Upset and Nausea: Tannins can increase stomach acid, leading to nausea, acid reflux, or heartburn.
  • Diarrhea: In high amounts, caffeine can act as a laxative by stimulating the colon muscles, leading to more frequent bowel movements.

Serious but Rare Side Effects

While uncommon, certain severe adverse effects have been reported, primarily linked to concentrated extracts rather than traditional tea consumption.

Liver toxicity

Cases of liver injury have been associated with high-dose Camellia sinensis extracts. The risk is rare and the exact reasons are not fully understood, but it may involve high levels of EGCG (epigallocatechin gallate) or interactions with medications. Symptoms of liver toxicity to watch for include nausea, abdominal pain, dark urine, and jaundice.

Nutrient absorption problems

The polyphenols and tannins in tea can interfere with the body's ability to absorb certain nutrients, most notably iron and calcium. This is a particular concern for individuals with pre-existing deficiencies.

  • Iron Deficiency: Tea can hinder the absorption of non-heme iron from plant-based foods. Consuming tea between meals rather than with them can help mitigate this effect.
  • Reduced Calcium Absorption: Excess tea consumption, especially in those with pre-existing bone weakness like osteoporosis, can increase calcium excretion through urine.

Potential Drug Interactions

Camellia sinensis can interact with a range of medications, amplifying or reducing their intended effects. It's crucial to consult a healthcare provider if you are taking any medication and regularly consume tea or its extracts.

  • Blood Thinners: The vitamin K content and other compounds in green tea can affect blood clotting, potentially reducing the effectiveness of medications like warfarin.
  • Heart and Blood Pressure Medication: Green tea can affect medications such as nadolol (a beta-blocker) and some statins (e.g., atorvastatin), potentially decreasing their absorption.
  • Stimulants: Combining the caffeine in tea with other stimulants, like those for ADHD or decongestants, can lead to overstimulation, increased heart rate, and high blood pressure.

Minimizing Your Risk of Side Effects

Adopting safe consumption habits can help mitigate the risk of experiencing adverse effects. The key is moderation and awareness of your own body's sensitivities.

  • Watch Your Intake: Limiting regular consumption to around 3-5 cups per day is often recommended, with some sources noting up to 8 cups is safe for most people, but more than that significantly increases risk.
  • Drink With Food: To avoid stomach irritation and minimize nutrient malabsorption, consume tea after meals rather than on an empty stomach.
  • Avoid Concentrated Extracts: Extracts often contain much higher concentrations of catechins and are more frequently associated with severe side effects like liver damage. Stick to traditional brewed tea unless advised by a healthcare professional.
  • Time Your Consumption: If you are sensitive to caffeine, avoid drinking tea in the hours leading up to bedtime to prevent sleep disruption.
  • Know Your Health Profile: Individuals with pre-existing conditions like anemia, IBS, heart problems, or liver disease should be particularly cautious or avoid high intake.

Side Effects of Camellia sinensis Consumption: Brewed Tea vs. Concentrated Extract

Feature Brewed Tea (Moderate Intake) Concentrated Extract (Supplements)
Caffeine Content Moderate, varies by brewing method. High, often much higher than tea.
Tannin Concentration Sufficient to cause irritation on empty stomach. Possibly higher, but less relevant than EGCG concentration.
Liver Toxicity Risk Very rare; extremely low risk in healthy individuals. Rare but documented; associated with high doses.
Digestive Issues Possible with high intake or on empty stomach. Higher risk due to high dose of active compounds.
Drug Interactions Potential for interactions, but dose-dependent. Higher risk of interactions due to concentrated dose.
Overall Safety Generally considered safe for most people. Requires greater caution, especially for long-term use.

Conclusion

While a widely celebrated beverage, knowing what are the side effects of Camellia sinensis is essential for everyone, especially those with sensitivities or health conditions. For most, moderate consumption of brewed tea poses minimal risk, with minor side effects typically limited to mild digestive issues or caffeine-related symptoms. The most serious risks, such as liver toxicity, are overwhelmingly linked to the high doses found in concentrated extracts. By consuming tea in moderation, avoiding it on an empty stomach, and being aware of potential drug interactions, individuals can enjoy the benefits of Camellia sinensis while minimizing their risk of adverse reactions. As with any herbal product, consulting a healthcare professional before making significant changes to your intake, particularly with extracts, is the safest approach. More detailed safety information on Camellia sinensis extract can be found on authoritative sites like the Therapeutic Goods Administration (TGA).

Frequently Asked Questions

Yes, excessive consumption of Camellia sinensis, particularly green tea or other tea varieties high in caffeine, can cause or worsen anxiety, jitteriness, and restlessness in some individuals.

Drinking Camellia sinensis tea on an empty stomach can increase stomach acid due to its tannin content, which may cause nausea, stomach pain, or acid reflux in sensitive people. It is often recommended to consume it with or after a meal.

The risk of liver damage is very rare and is primarily associated with high doses of concentrated Camellia sinensis extracts found in supplements, not from drinking moderate amounts of brewed tea.

The tannins and polyphenols in Camellia sinensis can bind to non-heme iron from plant sources and affect calcium balance, potentially inhibiting their absorption. This is more significant with high consumption.

If you are on blood thinners like warfarin, you should be cautious with Camellia sinensis intake. Consult your doctor, as tea contains small amounts of vitamin K, which can affect the medication's effectiveness.

For most healthy adults, drinking up to 8 cups of brewed tea daily is generally considered safe. However, the optimal amount varies, and individuals sensitive to caffeine should limit their intake to lower amounts.

Yes, pregnant and breastfeeding women should limit their caffeine intake, including from Camellia sinensis. High intake has been linked to increased risk of miscarriage and can cause irritability and sleep issues in breastfed infants.

References

  1. 1
  2. 2
  3. 3

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.