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What are the side effects of eating aloe vera? A guide to risks and safe consumption

5 min read

According to the National Center for Complementary and Integrative Health, short-term use of oral aloe gel is generally considered safe, but consuming the yellow aloe latex can cause severe health problems. Understanding what are the side effects of eating aloe vera? depends critically on which part of the plant you consume.

Quick Summary

The risks of consuming aloe vera vary significantly between the inner gel and the bitter yellow latex. Latex consumption can lead to severe digestive issues, dehydration, and potential organ damage, while the gel is mostly safe for short-term internal use. Caution is advised, especially for long-term use.

Key Points

  • Gel vs. Latex: The clear gel is generally safe for short-term internal use, but the yellow latex contains anthraquinones that can cause severe side effects when ingested.

  • Digestive Issues: Consuming aloe latex can lead to severe abdominal cramps, diarrhea, and vomiting due to its strong laxative effect.

  • Organ Damage Risk: High-dose or long-term ingestion of aloe latex can cause dangerous electrolyte imbalances, dehydration, kidney damage, and, in rare cases, acute hepatitis.

  • Drug Interactions: Oral aloe can interfere with the effectiveness of medications for diabetes, heart conditions (digoxin), and blood thinners (warfarin), increasing the risk of adverse effects.

  • Vulnerable Populations: Oral aloe latex is unsafe for pregnant or breastfeeding women, children under 12, and individuals with intestinal or kidney conditions.

  • Proper Preparation: To safely consume the gel from a raw plant, it is essential to drain and thoroughly rinse the leaf to remove all traces of the toxic latex.

In This Article

Understanding the Aloe Vera Plant: Gel vs. Latex

The aloe vera leaf is composed of three distinct parts: the tough outer rind, the bitter yellow layer of liquid called latex located just under the skin, and the clear inner gel. It is crucial to distinguish between these parts, as their safety for consumption differs dramatically. The gel is the part typically used in food products and health drinks, while the latex contains compounds, particularly anthraquinones like aloin, that give it strong laxative effects and cause most of the serious side effects. Many of the health warnings surrounding oral aloe vera refer specifically to the latex or whole-leaf extracts that contain it.

Side Effects of Consuming Aloe Latex and Whole-Leaf Extract

Consuming the bitter yellow latex or whole-leaf aloe products that have not had the latex completely removed carries a range of significant health risks. This is why the U.S. Food and Drug Administration (FDA) banned the use of aloe latex in over-the-counter laxatives in 2002.

Digestive System Complications

  • Severe cramping and pain: The anthraquinones in aloe latex are powerful irritants to the gastrointestinal tract, causing painful stomach cramps.
  • Diarrhea and vomiting: The laxative effect can lead to persistent and severe diarrhea and vomiting.
  • Melanosis coli: Chronic, long-term use of aloe latex can cause discoloration of the colon, visible during a colonoscopy.

Dehydration and Electrolyte Imbalance

  • Hypokalemia: Severe and prolonged diarrhea can lead to a dangerous drop in the body's potassium levels, a condition known as hypokalemia.
  • Cardiovascular risks: Low potassium can increase the risk of adverse effects from certain heart medications like digoxin.
  • Kidney damage: The combination of dehydration and electrolyte imbalance can put a severe strain on the kidneys, potentially leading to kidney failure, especially with high doses over a long period.

Potential Carcinogenic Effects

Based on animal studies, the International Agency for Research on Cancer (IARC) has classified non-decolorized whole-leaf aloe vera extract as a possible human carcinogen (Group 2B). While this specific form is not commonly used by consumers and is different from purified gel products, it highlights the risks associated with anthraquinone compounds found in the latex.

Reproductive and Other Serious Risks

  • Pregnancy and breastfeeding: Oral consumption of aloe latex is considered unsafe during pregnancy as it can stimulate uterine contractions, potentially causing miscarriage. It is also not recommended for breastfeeding mothers, as the compounds can be transferred to the infant through breast milk.
  • Acute hepatitis: In rare cases, consumption of aloe leaf extracts has been linked to acute hepatitis, a severe inflammation of the liver.

Considerations for Oral Aloe Vera Gel

In contrast to the latex, the clear inner gel is generally considered safer for short-term consumption. Clinical studies have shown short-term use of aloe gel (e.g., up to 42 days at 15 mL daily) to be safe for many people. However, it is not completely without risk and can still cause mild digestive discomfort in some individuals. Furthermore, commercial oral products can vary in their manufacturing process and aloin content, so selecting a high-quality, reputable brand is important. Products certified by the International Aloe Science Council have a low aloin content, typically less than 10 parts per million.

Who Should Avoid Oral Aloe Vera?

Certain individuals should avoid consuming oral aloe vera, especially products containing latex or whole-leaf extract, to minimize health risks. This includes:

  • Pregnant and breastfeeding women: Due to the risk of uterine contractions and potential harm to the infant.
  • Children under 12: Aloe latex and whole-leaf extracts are considered unsafe for this age group.
  • Individuals with intestinal conditions: Those with conditions like Crohn's disease, ulcerative colitis, or bowel obstruction should avoid aloe latex, as it is a gastrointestinal irritant.
  • Anyone with kidney problems: High doses of aloe latex have been linked to kidney damage and failure.
  • People with allergies: Individuals with allergies to plants in the Liliaceae family (like garlic, onions, or tulips) may be more prone to allergic reactions to aloe.

Drug Interactions with Oral Aloe Vera

Before taking any form of oral aloe vera, especially if you are on medication, it is crucial to consult a healthcare provider. Aloe can interact with several types of drugs, potentially increasing side effects or reducing effectiveness.

Medication Type Potential Interaction with Oral Aloe Associated Risk
Diabetes Medications Can lower blood sugar levels. Risk of hypoglycemia (blood sugar dropping too low).
Blood Thinners (e.g., Warfarin) May slow blood clotting. Increased risk of bruising and bleeding.
Digoxin (Lanoxin) Latex can lower potassium levels. Increased risk of digoxin side effects due to low potassium.
Diuretics (Water Pills) Latex can cause further potassium loss. Dangerously low potassium levels.
Stimulant Laxatives Latex is also a stimulant laxative. Excessive diarrhea, fluid loss, and severe dehydration.
Oral Medications Latex can speed up bowel transit. Reduced absorption and decreased effectiveness of medication.

How to Safely Prepare Aloe Vera at Home

If you choose to consume aloe vera gel from a live plant, proper preparation is essential to remove the harmful latex.

  1. Select the right leaf: Choose a mature, healthy leaf from an edible Aloe vera barbadensis Miller plant.
  2. Cut and drain: Cut the leaf from the base and stand it upright in a bowl for 10-15 minutes. This allows the yellow latex to drain out.
  3. Wash thoroughly: After draining, wash the leaf to remove any residual latex.
  4. Extract the gel: Slice the leaf lengthwise and use a spoon to scoop out only the clear inner gel.
  5. Rinse again: Rinse the extracted gel cubes thoroughly under cool water to ensure all bitter latex residue is gone.

Conclusion

While topical application of aloe vera gel is widely recognized as safe for soothing minor burns and skin irritations, internal consumption requires far more caution. The distinction between the clear inner gel and the yellow latex is the most important takeaway. The gel is generally safe for short-term oral use, especially when properly prepared to remove all traces of latex. However, the latex, which is a powerful laxative, carries significant health risks, including severe digestive problems, electrolyte imbalance, kidney damage, and potential carcinogenic effects. Given the complexities and risks, especially concerning drug interactions, it is always best to consult a healthcare professional before incorporating oral aloe vera into your diet, particularly for long-term use or if you have pre-existing health conditions.

For more in-depth medical guidance, refer to the resources from the National Center for Complementary and Integrative Health.

Frequently Asked Questions

Yes, but only if you consume the clear inner gel and ensure all traces of the yellow latex are drained and rinsed away. The latex contains compounds that are toxic when ingested and can cause severe side effects.

Accidentally consuming aloe latex can cause severe abdominal cramping, diarrhea, and vomiting. If a large amount is ingested, seek immediate medical attention, as it can lead to more serious complications.

Yes, high doses and prolonged use of aloe latex can cause kidney damage and, in severe cases, kidney failure. The laxative effect leads to dehydration and an electrolyte imbalance, which stresses the kidneys.

No, oral aloe vera latex is considered unsafe during pregnancy because it can stimulate uterine contractions and lead to miscarriage. It is also not recommended for breastfeeding mothers as the components can affect the infant.

Yes, oral aloe can interact with several medications, including those for diabetes, heart conditions (like digoxin), blood thinners (like warfarin), and diuretics. It can lower blood sugar, increase bleeding risk, or cause dangerously low potassium levels.

Different aloe products contain different parts of the plant. The safety depends on the processing. High-quality products use decolorized, purified gel with very low levels of aloin, but whole-leaf extracts and those containing latex are not safe for internal use.

For oral products like juices, look for labels stating that the product is 'purified' or 'decolorized' and contains very low levels of aloin (less than 10 ppm). Look for certifications from the International Aloe Science Council (IASC).

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.