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What Are the Side Effects of Isomalto Oligosaccharide Powder?

4 min read

A study documented on the Canada.ca website indicated that consuming more than 30 grams of isomalto oligosaccharide (IMO) per day may lead to various gastrointestinal problems. While a popular prebiotic, understanding what are the side effects of isomalto oligosaccharide powder is crucial for anyone using it as a supplement or consuming it in processed foods.

Quick Summary

The primary side effects of isomalto oligosaccharide powder include dose-dependent gastrointestinal issues like bloating, gas, and diarrhea, particularly in sensitive individuals. Some industrial versions may also impact blood sugar levels.

Key Points

  • Gastrointestinal Discomfort: The most common side effects are gas, bloating, and diarrhea, which are dose-dependent and caused by fermentation in the colon.

  • Blood Sugar Impact: Some commercial, industrially produced IMO powders can cause a significant blood glucose spike, contrary to low-glycemic claims, which is a risk for diabetics.

  • Sensitivity to FODMAPs: Individuals with IBS, SIBO, or a general FODMAP sensitivity are more likely to experience adverse digestive effects from IMO.

  • Moderate Doses are Key: Side effects are typically minimized by starting with a low dose (e.g., 5-10g) and not exceeding around 30g per day, though tolerance is individual.

  • Read Labels Carefully: IMO is a hidden ingredient in many 'low-sugar' or 'high-fiber' products like protein bars, so total intake can be higher than expected.

In This Article

Understanding Isomalto Oligosaccharide Powder

Isomalto oligosaccharide, commonly known as IMO, is a mixture of short-chain carbohydrates used in the food industry as a low-calorie sweetener and a source of prebiotic fiber. Derived from starchy materials like corn, wheat, or tapioca, IMO powder is a digestion-resistant substance. This means it passes through the small intestine largely undigested and is then fermented by beneficial bacteria in the colon, such as Bifidobacteria. This fermentation process is what provides its prebiotic benefits but is also the direct cause of most of its side effects. IMO is a fermentable oligosaccharide, and depending on the manufacturing process, the final product can vary in its composition and digestibility.

Common Gastrointestinal Side Effects

The most frequently reported side effects of isomalto oligosaccharide powder are gastrointestinal. These issues are directly linked to the fermentation process that occurs in the large intestine. When IMO reaches the colon, the gut microbiota ferments it, producing gases in the process.

  • Bloating and Gas: This is one of the most common complaints, especially when consuming larger amounts. The gas produced during fermentation can lead to a feeling of fullness and abdominal distension.
  • Diarrhea and Soft Stool: High dosages of IMO powder can have a laxative effect, resulting in soft stools or diarrhea. This happens because the undigested carbohydrates pull water into the colon. Health Canada data mentions that intake over 30g/day can trigger these symptoms, while other sources note that doses greater than 40g/day are more likely to cause significant issues.
  • Abdominal Discomfort: Along with bloating and gas, some individuals experience general abdominal discomfort or cramping due to the increased fermentation and changes in bowel motility.

Who is Most at Risk for GI Side Effects?

Certain individuals are more susceptible to the digestive side effects of IMO powder. Since IMO is a FODMAP (fermentable oligo-, di-, mono-saccharides and polyols), people with conditions related to carbohydrate malabsorption or gut sensitivity are particularly vulnerable.

  • Irritable Bowel Syndrome (IBS): People with IBS, whose digestive systems are highly sensitive, may find that IMO exacerbates their symptoms of bloating, gas, and abdominal pain.
  • Small Intestinal Bacterial Overgrowth (SIBO): In individuals with SIBO, excess fermentation can occur prematurely in the small intestine, leading to excessive gas and bloating.
  • FODMAP Intolerance: For those following a low-FODMAP diet, IMO is a high-FODMAP ingredient that should be avoided.

Impact on Blood Sugar and Insulin

Some studies suggest that the claim that industrial IMO is low-glycemic may be misleading, especially regarding certain manufacturing processes. The digestibility of IMO can vary, with some preparations containing a higher percentage of smaller saccharides that are more easily digested.

One study found that consumption of industrial IMO syrup led to a significant increase in both blood glucose and insulin levels in healthy individuals, despite marketing as a low-carb alternative. This means that for diabetic individuals or those on ketogenic diets, IMO may not be a suitable option and could negatively impact blood sugar control. It is important to note that natural sources of IMO (like those found in honey or miso) are typically consumed in small quantities and do not pose the same risk.

How to Manage Isomalto Oligosaccharide Side Effects

To minimize the risk of experiencing adverse effects from IMO powder, consider the following strategies:

  1. Start Low and Go Slow: If you are new to IMO or other prebiotic fibers, begin with a very small dose (e.g., 5-10 grams per day) and gradually increase it over time. This allows your gut bacteria to adapt and can help reduce gas and bloating.
  2. Monitor Total Intake: Be aware that IMO is used in many commercial products, especially protein and energy bars. It's easy to unknowingly consume a high dose if you are not reading labels carefully.
  3. Check the Source: If you have concerns about blood sugar, research the specific brand and type of IMO, as digestibility and glycemic response can vary based on the manufacturing process.
  4. Stay Hydrated: Increasing your water intake can help manage the laxative effects associated with high fiber consumption.
  5. Consult a Professional: If you have a pre-existing gut condition like IBS or SIBO, or are diabetic, consult a healthcare provider or dietitian before incorporating IMO into your diet.

Comparison of IMO Side Effects with Other Prebiotic Fibers

Feature Isomalto Oligosaccharide (IMO) Inulin Fructo-Oligosaccharides (FOS)
Common GI Issues Bloating, gas, diarrhea, abdominal discomfort Bloating, gas, intestinal distress, especially in sensitive individuals Bloating, gas, diarrhea, particularly at higher doses
Dosage Tolerance Generally well-tolerated up to 30g/day, but issues may start at lower doses for some Often requires gradual introduction, high doses (>10-15g) are often problematic Side effects may be noticeable even at moderate doses for sensitive individuals
Blood Sugar Impact Some industrial versions can cause a significant glycemic response; not consistently low-glycemic Less likely to cause a blood sugar spike compared to IMO, but concerns exist Minimal impact on blood sugar due to non-digestibility
Suitability for SIBO/IBS High-FODMAP, generally not recommended as it can worsen symptoms High-FODMAP, problematic for most individuals with IBS or SIBO High-FODMAP, can cause symptoms in sensitive individuals

Conclusion

While isomalto oligosaccharide powder offers potential prebiotic benefits, its side effects are a significant consideration for many users. The most common issues, such as bloating, gas, and diarrhea, are directly related to the dose consumed and the individual's digestive sensitivity. Furthermore, the varying glycemic impact of industrial IMO contradicts some marketing claims and poses a risk for those managing blood sugar. To safely incorporate IMO into your diet, practice moderation, read product labels carefully, and consider your personal tolerance, especially if you have pre-existing digestive conditions. For a comprehensive overview of the product, including its approval status in Canada, you can refer to the official Health Canada documentation at Health Canada: Isomalto-oligosaccharide (VitaFiber).

Frequently Asked Questions

Yes, isomalto oligosaccharide powder is fermented by bacteria in the colon, which produces gas. This can lead to bloating and discomfort, especially if consumed in large quantities.

Yes, high dosages of IMO powder, typically over 30 grams per day, can cause a laxative effect leading to soft stools or diarrhea. Sensitivity varies by individual.

No, IMO is a high-FODMAP ingredient. It is generally not suitable for individuals following a low-FODMAP diet or those with IBS or SIBO, as it can worsen symptoms.

Some studies have shown that certain industrially produced IMO products can significantly raise blood glucose and insulin levels, challenging the claim that all IMO is low-glycemic. This is particularly relevant for diabetics.

While tolerance varies, gastrointestinal side effects are often reported at dosages above 30 grams per day. Starting with a smaller dose and slowly increasing can help manage tolerance.

IMO is used as a low-calorie sweetener and bulking agent that adds fiber, improving the texture and sweetness of products like protein bars while keeping net carbohydrate counts low on labels.

IMO's side effect profile is similar to other fermentable fibers like inulin or FOS. While some studies suggest it may produce less gas than FOS or XOS, individual tolerance is the most important factor.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.