What Are Steroidal Glycoalkaloids (SGAs)?
When people refer to "steroids in potatoes," they are actually talking about naturally occurring compounds known as steroidal glycoalkaloids (SGAs). Unlike anabolic steroids, which are synthetic drugs that mimic the male hormone testosterone, SGAs are complex organic molecules that are part of the plant's natural defense system. These compounds are found not only in potatoes but also in other members of the nightshade family, such as tomatoes and eggplants. The two most prominent SGAs in cultivated potatoes are alpha-solanine and alpha-chaconine.
The Chemical Makeup and Role in Plants
SGAs consist of a steroid backbone (aglycone) and one or more sugar units attached to it. For solanine and chaconine, the aglycone is the same—solanidine—but the sugar sidechains are different. This subtle difference in the sugar moiety significantly impacts their biological activity and toxicity. In the potato plant, these compounds act as a protective barrier, deterring herbivores and defending against fungal and bacterial pathogens. The concentration of SGAs is highest in parts of the plant not intended for consumption, such as the leaves, flowers, and sprouts, as well as in the skin of the tuber itself.
Factors That Increase Glycoalkaloid Levels
While modern potato cultivars have been selectively bred to keep SGA levels in the tubers low and safe for human consumption, several factors can cause the concentration to rise, particularly in the potato's surface layers.
- Light Exposure: One of the most common reasons for increased glycoalkaloids is exposure to light. This process also causes the potato to turn green due to the production of chlorophyll. While chlorophyll itself is harmless, its presence is a clear warning sign of a potential increase in solanine, as the two are produced simultaneously under the same conditions.
- Physical Damage: Any kind of mechanical damage, such as cuts, bruises, or impacts, will cause the potato to synthesize higher levels of SGAs as a protective response.
- Sprouting and Aging: As a potato ages and begins to sprout, the concentration of glycoalkaloids increases significantly in the sprouts and the area around the "eyes".
- Improper Storage: Storing potatoes in warm, bright places rather than cool, dark, and dry locations will accelerate the production of these compounds.
The Risks of High Glycoalkaloid Consumption
Potatoes with normal levels of glycoalkaloids pose no threat, but consuming potatoes with an excessively high concentration can cause illness. The accepted safe limit for total glycoalkaloids in fresh potatoes is generally considered to be 200 mg per kilogram of fresh weight.
Symptoms of solanine poisoning, which usually occur 30 minutes to 12 hours after consumption, include:
- Nausea and vomiting
- Diarrhea and abdominal pain
- Headaches and confusion
- A burning sensation in the mouth or throat (a taste indicator)
Can Peeling and Cooking Help?
Yes. Peeling and proper cooking are key to mitigating the risks posed by glycoalkaloids. Peeling can remove between 25% and 75% of the SGAs, as they are most concentrated in the skin. Furthermore, removing any green spots or sprouts is highly effective. Cooking methods, particularly frying at high temperatures, can help to reduce SGA content, although they are not completely destroyed by typical cooking. Crucially, if a potato has a bitter taste, it is best to discard it entirely, as this indicates a high level of toxins.
Comparing Potato Steroidal Glycoalkaloids and Phytosterols
Beyond glycoalkaloids, potatoes also contain other steroidal compounds called phytosterols. These are cholesterol-like compounds found in many plants, but their levels and effects differ significantly.
| Feature | Steroidal Glycoalkaloids (SGAs) | Phytosterols | 
|---|---|---|
| Primary Function | Plant defense against pests and pathogens | Cell membrane stability and structure | 
| Key Examples | Alpha-solanine, Alpha-chaconine | Beta-sitosterol, campesterol | 
| Location in Tuber | Highest concentration in skin, eyes, and green areas | Relatively evenly distributed, but overall content is low | 
| Toxicity Potential | High at elevated levels | Generally safe; some may have health benefits | 
| Flavor Profile | Bitter taste indicates high concentration | Does not typically affect potato flavor | 
| Consumer Relevance | Important for food safety and proper handling | Less relevant for potato safety; minimal nutritional contribution | 
Conclusion
Potatoes do not contain anabolic steroids or hormones that affect human physiology, but they do possess naturally occurring steroidal glycoalkaloids (SGAs) like solanine and chaconine. These compounds are part of the potato's defense system and are typically present at safe levels in commercial varieties. The risks of elevated SGA levels primarily arise from improper storage conditions, physical damage, and light exposure, which cause the potato to turn green or sprout. By storing potatoes properly, peeling off the skin, and removing any green or damaged parts, consumers can effectively minimize their exposure to these toxins and ensure their safety. A bitter taste is a crucial warning sign that should not be ignored. For more detailed information on glycoalkaloids and their effects, you can consult authoritative resources such as Cornell University's comprehensive page on Steroid alkaloids.
Additional Considerations on Plant Bioactives
Beyond the well-known SGAs, potatoes also contain other bioactive phytochemicals. For example, some varieties, especially purple or red ones, are rich in polyphenols and antioxidants like anthocyanins, which are concentrated in the skin. Yellow-fleshed potatoes contain lutein, a carotenoid antioxidant that supports eye health. These compounds generally contribute to the potato's nutritional value and are distinct from the potentially toxic SGAs. This illustrates the complexity of potato composition, where different compounds can have varying effects, some beneficial and others potentially harmful, depending on concentration and context.
Further Research and Breeding Efforts
Research continues into the biosynthesis and regulation of glycoalkaloids in potatoes, aiming to develop safer varieties. Scientists are exploring genetic manipulation to create potatoes with lower SGA content in the tubers while maintaining high levels in the foliage for pest resistance. Such advancements could eventually make potatoes even safer and easier to store without compromising the plant's natural defenses.
Overall, the key takeaway is that with a little knowledge about proper handling and storage, the risk associated with glycoalkaloids in potatoes is minimal for most consumers, and the vegetable can be enjoyed safely as part of a healthy diet.