Huberman's Evolving Stance on NMN Brands
Andrew Huberman, a neurobiologist at Stanford University and host of the Huberman Lab podcast, has shared information about his personal supplement routine. Regarding nicotinamide mononucleotide (NMN), his position on specific brands has seen changes. He has previously mentioned using NMN from Renue by Science, and his podcast has partnered with Momentous, which also offers NMN-related products. The landscape of his specific brand mentions is influenced by factors including product availability and sponsorships.
A significant development impacting NMN's market presence occurred in late 2022 and early 2023 when the FDA ruled that NMN could no longer be marketed as a dietary supplement. This regulatory change has required many companies to adjust their product labeling and marketing strategies. Huberman has stated he is no longer financially connected to any NMN manufacturer, aligning with his emphasis on an evidence-based approach to supplementation and prioritizing fundamental health behaviors like sleep and exercise.
Understanding NAD+ and Precursors Like NMN
For those interested in how NMN functions, it's important to know about NAD+ (nicotinamide adenine dinucleotide). NAD+ is a coenzyme crucial for many cellular processes, including energy metabolism and DNA repair. NAD+ levels naturally decline with age. NMN and nicotinamide riboside (NR) are considered precursors to NAD+, meaning the body can convert them into NAD+.
Huberman's approach to supporting his NAD+ levels has involved incorporating both NMN and NR into his routine. He has discussed taking NMN, often in a sublingual powder form, which he has suggested may offer enhanced absorption. He has also mentioned taking NR, typically in capsule form.
The Rationale Behind Huberman's NMN and NR Use
Huberman's primary motivation for using NAD+ precursors like NMN and NR appears to be related to the subjective benefits he perceives in his daily life. While animal studies have explored potential longevity aspects of NAD+ boosters, Huberman has highlighted experiencing a more consistent level of mental and physical energy as a key personal benefit. He has noted feeling a decrease in energy when he stops taking these supplements, suggesting that individual response is a significant factor in his decision-making regarding supplementation. This perspective aligns with his broader philosophy that while supplements can be supportive tools, they should complement a strong foundation of optimal lifestyle practices.
Comparing NMN and NR
Both NMN and NR serve as precursors that the body can convert into NAD+, but there are some distinctions in how they are understood and utilized.
| Feature | NMN (Nicotinamide Mononucleotide) | NR (Nicotinamide Riboside) |
|---|---|---|
| Conversion Pathway | Thought to be converted relatively directly into NAD+ | Converted into NMN before becoming NAD+ |
| Form Mentioned by Huberman | Often mentioned as a sublingual powder for absorption | Typically mentioned in capsule form |
| Regulatory Status (FDA) | Subject to FDA regulatory actions impacting its sale as a dietary supplement | Not currently facing the same specific regulatory scrutiny as NMN |
| Huberman's Potential Benefit Focus | Supports sustained mental and physical energy | Used alongside or in alternation with NMN for similar energy support |
Considerations for NMN Supplementation
If you are considering NMN supplementation, learning from figures like Huberman involves understanding the principles behind their choices rather than simply replicating them. Here is a guide to a thoughtful approach:
- Prioritize Fundamental Health: Huberman consistently stresses that foundational behaviors such as adequate sleep, proper nutrition, and regular exercise are the most critical factors for health and well-being. Supplements are considered secondary tools.
- Consult a Healthcare Provider: Before beginning any new supplement, particularly compounds like NMN with evolving research and regulatory status, it is advisable to consult with a qualified healthcare professional. They can provide guidance based on your individual health needs.
- Focus on Product Quality: Rather than focusing solely on which brand someone else uses, prioritize finding high-quality NMN products. Look for companies that provide third-party testing and demonstrate transparency in their sourcing and manufacturing processes. Huberman's past associations, like with Momentous, suggest he values partners who align with a science-informed perspective.
- Monitor Individual Response: If you choose to take NMN, pay close attention to how your body responds. Individual experiences with supplements can vary.
- Stay Informed: Keep up-to-date with current research and regulatory information surrounding NMN and other supplements. Resources like scientific publications and updates from regulatory bodies can be helpful. The Huberman Lab podcast itself is a source where he may discuss new findings and adjustments to his practices.
Conclusion: Making Informed Supplement Choices
While there is interest in knowing the specific brand of NMN Andrew Huberman uses, the more significant takeaway from his discussions is the emphasis on a considered and science-informed approach to supplementation. He has mentioned using NMN from different sources over time, including Renue by Science, and has been associated with Momentous, reflecting the dynamic nature of the supplement landscape and affiliations. Recent regulatory actions by the FDA further highlight that the market for NMN is subject to change. The most valuable lesson is to prioritize foundational health practices, research product quality diligently, and make decisions based on your personal health needs and the current scientific understanding, rather than exclusively on brand endorsements. Making informed choices is key.
