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What Does Bisglycinate Help With? Benefits for Sleep, Digestion, and More

4 min read

Studies suggest that a significant portion of the population may not be meeting their daily mineral requirements, prompting many to seek supplements. Bisglycinate helps address this deficit by offering a highly absorbable and gentle-on-the-stomach way to supplement essential minerals like magnesium, iron, and zinc.

Quick Summary

Bisglycinate is a form of chelated mineral, known for superior absorption and tolerability compared to standard mineral salts. It provides benefits for sleep, mood, muscle relaxation, immune function, and digestive health by delivering nutrients efficiently.

Key Points

  • Superior Absorption: Bisglycinate is a chelated mineral form that is highly bioavailable, allowing for more efficient absorption by the body compared to standard mineral salts.

  • Gentle on Digestion: Its structure makes bisglycinate significantly gentler on the stomach, reducing common side effects like upset, diarrhea, and constipation.

  • Aids Sleep and Relaxation: Magnesium bisglycinate, combined with the amino acid glycine, is particularly effective at calming the nervous system and improving sleep quality.

  • Reduces Anxiety and Stress: By helping to regulate neurotransmitters and stress hormones, bisglycinate can promote a sense of calm and well-being.

  • Supports Multiple Functions: Depending on the mineral (magnesium, iron, zinc), bisglycinate can boost energy, strengthen immunity, and support healthy skin and muscles.

  • Addresses Deficiencies Effectively: Due to its high absorption rate, bisglycinate is an excellent choice for individuals looking to correct mineral deficiencies with minimal side effects.

In This Article

Understanding the Bisglycinate Advantage

Bisglycinate is a mineral compound where a mineral, such as magnesium, iron, or zinc, is chelated, or bonded, to two molecules of the amino acid glycine. This unique structure is the key to its effectiveness. The amino acid carrier shields the mineral, preventing it from reacting with other compounds in the gut that could inhibit its absorption. As a result, bisglycinate is highly bioavailable, meaning a larger portion of the mineral is absorbed and utilized by the body.

This gentle absorption process also makes bisglycinate-based supplements much easier on the digestive system compared to other mineral forms, which often cause side effects like stomach upset, gas, or diarrhea. The specific benefits of bisglycinate depend on the mineral it carries, with each offering a targeted approach to enhancing well-being.

Key Bisglycinate Minerals and Their Benefits

Magnesium Bisglycinate

This is perhaps the most popular form of bisglycinate, prized for its calming and relaxing properties. Its benefits are numerous:

  • Improved Sleep Quality: The combination of magnesium and glycine supports neurotransmitters like GABA, which promotes relaxation and helps reduce the time it takes to fall asleep. Many users report a more restful night's sleep without daytime drowsiness.
  • Anxiety and Stress Reduction: Magnesium bisglycinate helps regulate the body's stress hormones, such as cortisol, and supports a balanced nervous system. This can lead to a more stable mood and reduced feelings of tension and anxiety.
  • Muscle Relaxation: Magnesium is essential for proper muscle function, helping to alleviate cramps, spasms, and general tension. It is a popular choice for athletes and individuals with muscle soreness.

Iron Bisglycinate

For those needing to supplement iron, bisglycinate offers a significantly gentler alternative to conventional iron salts like ferrous sulfate, which are notorious for causing constipation and digestive upset.

  • Enhanced Energy Levels: By effectively replenishing iron stores, bisglycinate helps prevent fatigue and supports the production of hemoglobin, which transports oxygen throughout the body.
  • Improved Blood Health: Iron is critical for the formation of red blood cells, and its high absorption from this form helps address iron deficiency anemia more comfortably.

Zinc Bisglycinate

Zinc is a vital mineral for numerous bodily functions, and the bisglycinate form ensures efficient uptake, unhindered by other dietary compounds like phytates.

  • Immune System Support: Zinc is crucial for the development and function of immune cells. A bisglycinate supplement helps maintain strong immunity, especially during vulnerable periods.
  • Skin Health and Healing: It aids in tissue repair and has anti-inflammatory properties, making it beneficial for conditions like acne and supporting wound healing.
  • Hormonal Balance: Zinc plays a key role in hormonal regulation, including testosterone synthesis, and supports reproductive health.

Bisglycinate vs. Other Mineral Forms

Choosing the right mineral supplement depends on your specific needs, but the bisglycinate form offers distinct advantages, particularly regarding absorption and digestive comfort. Here is a comparison highlighting the key differences:

Feature Bisglycinate (e.g., Magnesium) Other Form (e.g., Magnesium Oxide/Citrate)
Absorption Superior; chelation with glycine significantly increases bioavailability. Variable; Oxide is poorly absorbed, while citrate is well-absorbed but has laxative effects.
Digestive Tolerance Excellent; glycine protects the mineral, leading to minimal to no stomach upset. Poor to moderate; Can cause diarrhea (citrate) or constipation (oxide, sulfate).
Specific Benefit (Sleep) Enhanced calming effect from both magnesium and glycine. Calming effect primarily from magnesium, but potential digestive issues can disrupt sleep.
Best For Long-term daily supplementation, individuals with sensitive digestion, stress and sleep support. Short-term relief (e.g., constipation with citrate) or for those tolerant to side effects.
Glycine Benefits The glycine carrier molecule provides its own calming effects on the nervous system. No additional calming benefits from the carrier molecule.

Practical Tips for Taking Bisglycinate

To maximize the effectiveness of bisglycinate supplements, consider these practical tips:

  • Timing: For sleep benefits, take magnesium bisglycinate about 30-60 minutes before bed. For other purposes, like energy or general well-being, it can be taken morning or night. Zinc is often best taken with food to minimize nausea.
  • Dosage: Follow the recommended dosage on the product label or as advised by a healthcare professional. Splitting the dose throughout the day can sometimes improve absorption and minimize potential side effects.
  • Avoid Inhibitors: For iron bisglycinate, avoid taking it at the same time as dairy products, coffee, or tea, as these can inhibit absorption.

Considerations and Side Effects

While bisglycinate is generally well-tolerated, some individuals may still experience mild digestive discomfort, especially when first starting supplementation or taking high doses. As with any supplement, consulting a healthcare professional is recommended, particularly if you have pre-existing health conditions or are taking other medications. For instance, high-dose zinc supplementation over a long period can interfere with copper absorption, a factor a doctor should monitor.

Conclusion

In summary, bisglycinate is a superior and highly effective form for supplementing essential minerals due to its chelated structure with glycine. What does bisglycinate help with? It offers significant benefits for improving sleep quality, reducing anxiety, supporting muscle function, boosting immune health, and enhancing energy levels, all while being gentle on the digestive system. For those who experience issues with traditional mineral supplements, switching to the bisglycinate form can provide a much-needed solution for optimal health and wellness.

For more detailed information on specific minerals and their functions, you can consult reliable sources like the National Institutes of Health (NIH) Office of Dietary Supplements. [https://ods.od.nih.gov/]

Frequently Asked Questions

Bisglycinate refers to a mineral (such as magnesium, iron, or zinc) that has been chelated, or bonded, to two molecules of the amino acid glycine. This bonding enhances the mineral's absorption and makes it gentle on the digestive system.

For many, yes. Bisglycinate typically offers superior bioavailability and is significantly gentler on the digestive tract compared to other common forms like magnesium oxide or iron sulfate, which can cause constipation or upset stomach.

Magnesium bisglycinate is highly effective for sleep due to its ability to increase GABA production, a calming neurotransmitter, and lower cortisol levels. The added glycine further enhances relaxation, promoting faster sleep onset and better sleep quality.

Yes, magnesium bisglycinate is often recommended for anxiety. The combination of magnesium and glycine has a calming effect on the nervous system, helping to regulate stress hormones and promote a sense of calm.

Bisglycinate is known for being gentle on the stomach and is much less likely to cause digestive issues like diarrhea or constipation than other mineral forms. However, as with any supplement, some individual sensitivity is possible.

Iron bisglycinate is often a preferred form of iron during pregnancy due to its high absorption and lower risk of causing digestive side effects like constipation. However, pregnant women should always consult a healthcare provider before taking any supplement.

The best time depends on your goal. For sleep, take magnesium bisglycinate 30-60 minutes before bed. For energy or general wellness, it can be taken morning or night, often with food to enhance absorption.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.