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What is a DGL supplement? A Complete Guide to Deglycyrrhizinated Licorice

6 min read

Ancient civilizations used licorice root for thousands of years to aid digestion. Today, a specialized form called a DGL supplement, or deglycyrrhizinated licorice, offers the same soothing benefits for gut health without the common side effects associated with regular licorice.

Quick Summary

A DGL supplement is an extract of licorice root with the glycyrrhizin compound removed, making it a safer option for supporting digestive health by boosting mucosal protection.

Key Points

  • What is DGL: DGL stands for deglycyrrhizinated licorice, a form of licorice root extract with the glycyrrhizin compound removed to eliminate adverse side effects like elevated blood pressure.

  • Works by Protecting the Gut Lining: Instead of blocking acid, DGL stimulates the production of mucin, a protective mucus that coats and soothes the stomach and esophageal lining.

  • Effective for Digestive Issues: DGL is used to alleviate symptoms of heartburn, GERD, and can promote the healing of peptic and duodenal ulcers.

  • Chewable Form is Optimal: For maximum effectiveness, DGL should be taken as a chewable tablet about 20 minutes before a meal, as saliva activates the therapeutic compounds.

  • Superior to Regular Licorice: Due to the removal of glycyrrhizin, DGL is a much safer option for long-term digestive support than traditional licorice root.

  • Safe for Long-Term Use: DGL's favorable safety profile allows for continuous use, but medical supervision is always recommended before starting any long-term supplement regimen.

In This Article

Understanding DGL: The Safer Licorice

Deglycyrrhizinated licorice, or DGL, is a specially processed form of the licorice root (Glycyrrhiza glabra). For centuries, the licorice root has been used in traditional medicine across Europe and Asia for its various healing properties. However, the whole root contains a compound called glycyrrhizin, which, when consumed in large amounts or over long periods, can cause potentially serious side effects. These side effects include elevated blood pressure, potassium depletion, fluid retention, and cardiac arrhythmias.

To create a DGL supplement, manufacturers perform a meticulous extraction process to remove the glycyrrhizin. This allows individuals to enjoy the beneficial effects of licorice on the digestive tract without the associated risks of the whole root. The remaining extract is rich in flavonoids and other compounds that provide the therapeutic benefits for which DGL is known. This difference is crucial for anyone seeking a safe, natural alternative for chronic digestive complaints.

The Mechanism: How DGL Soothes the Gut

Unlike conventional antacids and other acid-blocking medications that aim to reduce stomach acid, DGL works by supporting the body's own natural protective mechanisms. Its primary action is centered on strengthening and healing the mucosal lining of the stomach and intestinal wall.

How DGL Enhances Gastrointestinal Protection:

  • Stimulates Mucin Production: DGL stimulates the cells lining the digestive tract to produce more mucin, a slimy, protective substance. This mucus acts as a fortified barrier against the corrosive effects of stomach acid and other irritating substances.
  • Increases Blood Supply: Research indicates that DGL can increase the blood supply to the mucosal lining. This enhanced blood flow delivers vital nutrients and oxygen, which accelerates the healing of damaged tissues.
  • Boosts Cell Regeneration: DGL has been shown to increase the lifespan and regeneration of the cells that produce the protective mucus. This helps to maintain a strong and resilient gut barrier over time.
  • Possesses Antimicrobial Properties: Studies have explored DGL's potential to inhibit the growth of H. pylori, a bacteria known to cause some stomach ulcers and gastritis.

Key Benefits of DGL Supplements

Heartburn and GERD Relief

Many individuals with acid reflux and gastroesophageal reflux disease (GERD) find relief with DGL supplements. By thickening the protective mucus layer in the esophagus and stomach, DGL helps shield against the burning sensation caused by acid reflux. This makes it an excellent natural alternative for those looking to avoid or reduce their reliance on conventional acid-suppressing drugs.

Healing Peptic and Duodenal Ulcers

Clinical studies have long supported the use of DGL for treating and preventing peptic and duodenal ulcers. In some comparisons, DGL proved as effective as—or even more effective than—some prescription medications and antacids in promoting ulcer healing and preventing recurrence, all while having a far better safety profile. It works by stimulating the body's natural healing processes and protecting the stomach lining.

Soothing Mouth Sores (Canker Sores)

Recurrent aphthous stomatitis, or canker sores, is a painful condition that DGL may help resolve. A solution of powdered DGL used as a mouthwash has shown promising results in promoting faster healing and reducing pain.

General Digestive Support

DGL's demulcent properties help soothe inflammation and provide relief from general abdominal pain, burning sensations, and indigestion. By promoting a healthier, more resilient gastrointestinal tract, it can improve overall digestive comfort.

DGL vs. Traditional Licorice: A Comparison

Feature DGL (Deglycyrrhizinated) Traditional Licorice Root
Glycyrrhizin Content Minimally present or removed. Contains naturally high levels of glycyrrhizin.
Effect on Blood Pressure Considered safe for individuals with normal blood pressure. Can cause elevated blood pressure, especially with long-term use.
Risk of Side Effects Very low risk of mineralocorticoid effects like fluid retention and potassium loss. Higher risk of edema, hypertension, and hypokalemia with excessive intake.
Use for Digestion Recommended for long-term digestive support and healing of ulcers. Use with extreme caution and only for short durations for digestive issues due to side effect profile.
Recommended Form Most effective as chewable tablets, as mixing with saliva activates beneficial compounds. Often consumed as teas, candies, or extracts, requiring careful monitoring.

How to Properly Take a DGL Supplement

The form and timing of DGL are crucial for maximizing its effectiveness in supporting digestive health. Follow these guidelines for proper use:

  • Form: Choose chewable tablets over capsules for best results. The act of chewing and mixing DGL with saliva is thought to activate its beneficial compounds and ensure better coverage of the esophagus and stomach lining.
  • Timing: Take the supplement approximately 15 to 20 minutes before meals. This timing allows DGL to create a protective barrier in your stomach before food enters, providing maximum protection.
  • Dosage: Dosage can vary based on the specific product and manufacturer. A common therapeutic dose for acute issues is 380-760 mg taken two to three times per day. For maintenance, a lower daily dose may be sufficient. Always follow the label instructions or consult a healthcare professional.
  • Duration: DGL can be used for several months for chronic conditions like ulcers. Some protocols suggest a break after a certain period to assess the body's response.

Safety and Side Effects

Because the glycyrrhizin has been removed, DGL is generally well-tolerated and much safer for regular consumption than traditional licorice. Minor and infrequent side effects may include mild digestive upset when first starting the supplement. It is always wise to consult with a healthcare provider before beginning any new supplement, especially if you are pregnant, nursing, taking other medications, or have any underlying health conditions. DGL does not have the same risk profile as regular licorice, but medical guidance is always prudent.

Conclusion

A DGL supplement offers a compelling natural alternative for supporting and protecting digestive health. By utilizing the therapeutic properties of licorice root while removing the problematic glycyrrhizin, DGL provides a safe and effective way to address symptoms of heartburn, GERD, and ulcers. Its mechanism of action—boosting the body's own mucosal defenses—makes it a restorative and protective option rather than just a symptom-masking one. For those seeking relief from chronic digestive discomfort, DGL stands out as a powerful and well-tolerated herbal remedy. Before starting any new regimen, always consult a healthcare professional to ensure it is the right choice for your individual needs. For more scientific literature on licorice compounds, the National Institutes of Health provides a wealth of information.

Frequently Asked Questions

Question: How does a DGL supplement differ from regular licorice? Answer: A DGL supplement is made from licorice root that has had the glycyrrhizin compound removed. Regular licorice root contains this compound, which can cause elevated blood pressure and other side effects in some people.

Question: What are the main benefits of taking DGL? Answer: The primary benefits of DGL include soothing symptoms of heartburn and GERD, helping to heal peptic ulcers, protecting the stomach and esophageal lining, and providing relief for canker sores.

Question: Should DGL tablets be chewed or swallowed? Answer: DGL chewable tablets are the most effective form, as chewing and mixing with saliva are believed to activate the compounds that provide the soothing and protective benefits to the digestive tract.

Question: When is the best time to take a DGL supplement? Answer: For optimal results, it is recommended to take DGL approximately 15 to 20 minutes before meals. This allows it to create a protective barrier in the stomach and esophagus before you eat.

Question: Can DGL help heal ulcers caused by H. pylori? Answer: While not a primary antibiotic treatment, DGL may help inhibit the growth of H. pylori and promote the healing of ulcers caused by the bacteria by protecting the stomach lining.

Question: Is DGL safe for long-term use? Answer: Unlike regular licorice, DGL is generally considered safe for long-term use because the glycyrrhizin has been removed, eliminating the risk of mineralocorticoid-related side effects. However, consulting a healthcare provider is recommended for any long-term regimen.

Question: Are there any interactions between DGL and other medications? Answer: While DGL is much safer than traditional licorice, interactions can still occur, particularly with medications affecting potassium levels. Always consult your doctor or pharmacist to discuss potential interactions with your current medications.

Question: Can DGL raise blood pressure? Answer: DGL (deglycyrrhizinated licorice) is specifically processed to remove the compound that can raise blood pressure, making it a safe alternative for individuals with hypertension or those concerned about blood pressure issues from regular licorice.

Frequently Asked Questions

A DGL supplement is made from licorice root that has had the glycyrrhizin compound removed. Regular licorice root contains this compound, which can cause elevated blood pressure and other side effects in some people.

The primary benefits of DGL include soothing symptoms of heartburn and GERD, helping to heal peptic ulcers, protecting the stomach and esophageal lining, and providing relief for canker sores.

DGL chewable tablets are the most effective form, as chewing and mixing with saliva are believed to activate the compounds that provide the soothing and protective benefits to the digestive tract.

For optimal results, it is recommended to take DGL approximately 15 to 20 minutes before meals. This allows it to create a protective barrier in the stomach and esophagus before you eat.

While not a primary antibiotic treatment, DGL may help inhibit the growth of H. pylori and promote the healing of ulcers caused by the bacteria by protecting the stomach lining.

Unlike regular licorice, DGL is generally considered safe for long-term use because the glycyrrhizin has been removed, eliminating the risk of mineralocorticoid-related side effects. However, consulting a healthcare provider is recommended for any long-term regimen.

While DGL is much safer than traditional licorice, interactions can still occur, particularly with medications affecting potassium levels. Always consult your doctor or pharmacist to discuss potential interactions with your current medications.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.