Understanding the Core Concept
The term acceptable daily intake (ADI) not specified (often abbreviated as NS) is a classification used by international food safety bodies, primarily the Joint FAO/WHO Expert Committee on Food Additives (JECFA). This designation signifies that, following extensive scientific review, a substance is considered to have such low toxicity that a numerical daily intake limit is not required for human safety. This status is assigned when the estimated total dietary intake from appropriate uses, including natural occurrence and as an additive, is far below any level that would raise health concerns. The substance must always be used according to Good Manufacturing Practice (GMP).
The Criteria for "Not Specified" Status
To receive an ADI "not specified," a food additive must undergo a thorough safety evaluation based on all available chemical, biochemical, and toxicological data. The key criterion is that the total dietary exposure does not pose a health hazard. Use of these additives is guided by Good Manufacturing Practice (GMP). For more detailed information on GMP requirements and how the "not specified" status differs from other ADI classifications, refer to {Link: eufic.org https://www.eufic.org/en/understanding-science/article/qas-on-acceptable-daily-intakes-adis}.
How Consumers are Protected with this Status
Consumers can trust that substances with an ADI "not specified" have undergone rigorous safety evaluations by international and national regulatory bodies using all available scientific data. Good Manufacturing Practice (GMP) serves as a key safeguard, ensuring additives are used only to achieve their technological purpose and not in excessive amounts. This approach, supported by organizations like JECFA and EFSA, highlights the thoroughness of modern food safety assessments. The principle that additives should not hide poor food quality further protects consumers. For additional context on international food safety standards, consult World Health Organization fact sheets on food additives.
Conclusion: Safety by Design, Not by Absence of Data
The term "acceptable daily intake not specified" indicates a well-established scientific conclusion: the substance has very low toxicity and can be safely used in food production under GMP without needing a specific numerical daily limit. This status results from a comprehensive review of all available data, demonstrating high confidence from global health experts that the substance poses no hazard to health under approved conditions.
FAQs
What is the difference between ADI 'not specified' and 'no ADI allocated'?
An ADI 'not specified' means the substance has been evaluated and found safe under GMP, while 'no ADI allocated' can mean there was insufficient data for a full evaluation, or adverse effects were noted.
Does 'not specified' mean I can consume unlimited amounts?
No. The term is coupled with the condition of Good Manufacturing Practice (GMP). This means the substance should only be used at the lowest level necessary to achieve its technological effect, not in excessive quantities.
Which international body sets the 'not specified' status?
The Joint FAO/WHO Expert Committee on Food Additives (JECFA) is the primary international body that establishes the ADI and assigns the 'not specified' status after rigorous toxicological reviews.
Is an additive with 'not specified' status considered less safe than one with a numerical ADI?
No, the opposite is true. The 'not specified' status indicates a substance has such low toxicity that a numerical limit is not required, demonstrating a very high degree of safety under proper use.
Are there any E-numbers with an ADI 'not specified'?
Yes, many E-numbers, especially for common and low-toxicity additives like certain thickeners and natural colors, are given this status by EU regulatory bodies like EFSA.
Does an ADI 'not specified' apply to all people, including children and pregnant women?
Yes, the safety evaluations conducted by bodies like JECFA are designed to cover the general population, including sensitive subgroups, ensuring a wide margin of safety.
How does Good Manufacturing Practice (GMP) protect me?
GMP ensures that manufacturers use additives responsibly. This includes using only the minimal amount required, preventing their use to mask bad quality, and ensuring their technological benefit is clearly demonstrated.
