Skip to content

What is the best ketosis supplement?

6 min read

According to a study published in the Journal of Nutrition and Metabolism, exogenous ketones can increase blood ketone levels by 2-3 mmol/L within just 30 minutes, providing a rapid boost. This guide dives into what is the best ketosis supplement to help support your low-carb lifestyle, whether for weight loss, energy, or performance.

Quick Summary

This article evaluates various ketosis supplements, including MCT oil, BHB salts, and ketone esters, to help you make an informed choice. It covers their mechanisms, benefits, and potential side effects to support your goals while following a ketogenic diet.

Key Points

  • MCT Oil: A rapidly digested fat that boosts the body's natural ketone production for sustained energy and brain fuel.

  • Exogenous Ketones (BHB Salts): Directly introduce ketones to raise blood levels quickly, often used to accelerate ketosis or combat 'keto flu' symptoms.

  • Ketone Esters: A powerful liquid supplement for athletes, providing the most rapid and highest increase in blood ketones, but are costly and have a strong taste.

  • Electrolytes: Essential minerals like sodium, potassium, and magnesium that help alleviate 'keto flu' symptoms caused by water and mineral loss.

  • Choosing the Best: The ideal ketosis supplement depends on your goals—MCT oil for daily energy, BHB salts for quick boosts, and electrolytes for managing transition symptoms effectively.

In This Article

Understanding the Basics of Ketosis and Supplements

For those following a ketogenic diet, the body shifts from using glucose as its primary fuel source to burning fat for energy. This metabolic state is known as ketosis. While the diet alone is the most crucial factor, certain supplements can help support the process, particularly during the initial adaptation period known as the 'keto flu' or to enhance benefits like athletic performance and mental clarity. When assessing what is the best ketosis supplement, it is vital to understand the primary types available and what they aim to achieve.

Why Consider a Ketosis Supplement?

Supplements can offer several advantages for those on a keto diet:

  • Faster Entry into Ketosis: Exogenous ketone products can artificially raise blood ketone levels, helping users get into ketosis more quickly.
  • Relief from 'Keto Flu' Symptoms: Electrolyte supplements address the mineral imbalances that can cause symptoms like headaches and fatigue during the transition phase.
  • Enhanced Energy and Focus: Ketones provide a clean fuel source for the brain, and supplements like MCT oil or exogenous ketones can help sustain energy levels.
  • Improved Athletic Performance: Some athletes use supplements like ketone esters and MCT oil to support endurance and recovery.

Types of Ketosis Supplements Explained

MCT Oil

Medium-Chain Triglyceride (MCT) oil is a type of fat that the body rapidly converts into ketones, making it a popular choice for ketogenic dieters. It is a concentrated source of fats typically derived from coconut or palm kernels and is metabolized differently than the longer-chain fats found in most foods.

  • Mechanism: When ingested, MCTs bypass the typical digestive process and head straight to the liver, where they are converted into ketones for immediate use as fuel.
  • Benefits: It can help increase ketone levels, boost energy, and contribute to feelings of fullness, potentially aiding weight management. The C8 (caprylic acid) and C10 (capric acid) MCTs are the most ketogenic forms.
  • Considerations: Too much MCT oil can cause digestive issues like diarrhea. It also adds calories, so overconsumption could lead to weight gain.

Exogenous Ketone Salts (BHB Salts)

Exogenous ketones are ketone bodies supplied from an external source, typically in the form of Beta-Hydroxybutyrate (BHB) salts. These are powders containing BHB bonded to minerals such as sodium, potassium, calcium, or magnesium.

  • Mechanism: Upon consumption, the salt dissociates, releasing BHB into the bloodstream to directly raise blood ketone levels.
  • Benefits: They can help achieve ketosis more quickly and may assist in managing appetite and boosting athletic performance, though research is still emerging. They also provide electrolytes, which can be beneficial.
  • Considerations: High doses can lead to gastrointestinal distress and an excessive mineral load, especially sodium. The racemic BHB salts in most products contain a mix of both usable (D-BHB) and less understood (L-BHB) ketone forms.

Ketone Esters

Ketone esters are a more advanced, and often more expensive, form of exogenous ketone. They are liquids that provide a potent dose of ketones without the high mineral load of salts.

  • Mechanism: When the ester is broken down, a ketone precursor is released and converted into ketones, which can rapidly and significantly increase blood ketone levels.
  • Benefits: Studies show ketone esters can raise blood ketone levels to higher concentrations than salts and are often used by elite athletes to enhance endurance performance and recovery.
  • Considerations: They typically have a very bitter taste that many find unpalatable. They are also significantly more expensive than other options.

Comparison of Major Ketosis Supplements

Feature MCT Oil Exogenous Ketone Salts (BHB) Ketone Esters
Mechanism Stimulates liver to produce ketones from fat Directly introduces ketones into the bloodstream Directly introduces and stimulates ketone production
Primary Use Energy, sustained ketosis, appetite control Kickstarting ketosis, fast energy, managing keto flu Elite athletic performance, rapid and high-level ketosis
Effectiveness Moderately increases ketone levels, good for sustained state Rapidly increases blood ketones, but levels may not be as high as esters Very rapidly and substantially increases blood ketone levels
Side Effects Potential GI distress (diarrhea) if too much is consumed Possible GI issues and high mineral intake (especially sodium) Bitter taste is common, potential GI distress at high doses
Cost Generally affordable Moderately priced Typically very expensive
Form Liquid or powder Powder, capsules Liquid

Other Supportive Keto Supplements

Beyond the direct ketone sources, other supplements can significantly support a ketogenic diet, especially during the initial phase.

Electrolytes

During the first phase of the keto diet, the body excretes more water, leading to a loss of key electrolytes like sodium, potassium, and magnesium. Replenishing these can alleviate 'keto flu' symptoms. Look for keto-friendly electrolyte powders without sugar or excessive fillers.

Omega-3 Fatty Acids

Omega-3s, typically from fish or krill oil, are important for overall health and reducing inflammation. Since the keto diet is high in fat, ensuring a healthy balance of omega-3 to omega-6 fatty acids is crucial.

Digestive Enzymes

Transitioning to a high-fat diet can be hard on the digestive system for some, causing nausea or bloating. A digestive enzyme supplement containing lipase (to break down fat) can help.

Greens Powder

As the keto diet can be restrictive in terms of carbohydrates, some individuals may miss out on nutrients from certain vegetables. A greens powder can provide a convenient way to boost micronutrient intake.

How to Choose the Best Ketosis Supplement for You

Determining what is the best ketosis supplement depends heavily on your individual goals and tolerance.

  • For Sustained Ketosis and Energy: If your primary goal is to support sustained ketosis and energy levels throughout the day without the expense of exogenous ketones, MCT oil is likely your best bet. It's a natural and affordable way to promote ketone production from dietary fat.
  • For a Quick Boost or to Beat the Keto Flu: If you want a fast way to get into ketosis or overcome initial transition symptoms, BHB salts are a convenient and effective option. They offer a rapid spike in ketones and also provide electrolytes, which are essential during this period.
  • For Athletic Performance: For serious athletes looking to optimize endurance and recovery, and who are not sensitive to cost or taste, ketone esters may offer the most potent and rapid ketone boost.
  • For Nutritional Support: Don't overlook the importance of complementary supplements. Electrolytes are a foundational element for anyone starting keto to combat the 'keto flu'. Digestive enzymes can ease the transition to higher fat intake, and a greens powder can help fill potential nutrient gaps.

Remember that supplements are intended to support a properly formulated ketogenic diet, not replace it. Consistency in carbohydrate restriction remains the single most important factor for achieving and maintaining ketosis.

Conclusion

There is no single 'best' ketosis supplement for everyone, as the ideal choice depends on individual goals, budget, and physical tolerance. MCT oil is an accessible and effective option for sustained energy and boosting ketone production. BHB salts offer a rapid but temporary ketone increase, often used to help with keto adaptation. Ketone esters provide the most potent boost but come at a high cost and with taste challenges. Crucially, supporting supplements like electrolytes and digestive enzymes can make the transition to a keto diet smoother and address common issues. The best approach for most people is to start with a whole-foods ketogenic diet and introduce supportive supplements as needed, focusing on what helps them feel and perform their best. Consulting a healthcare provider or a registered dietitian is always recommended before starting any new supplement regimen.

For more detailed scientific information on the effects of exogenous ketones, consider reading reviews on PubMed, the National Library of Medicine database, for peer-reviewed studies on the subject: https://pubmed.ncbi.nlm.nih.gov/

Frequently Asked Questions

No, you do not need supplements. Ketosis is a metabolic state achieved by restricting carbohydrate intake. Supplements like MCT oil or exogenous ketones can help accelerate the process or support energy levels, but they are not essential.

While exogenous ketone supplements can temporarily increase blood ketone levels even with some carbohydrate intake, they do not replace the metabolic process of ketosis. Eating carbs can knock you out of true, sustained ketosis, and the exogenous ketones do not force the body to burn its own fat stores.

The most common side effects are gastrointestinal distress, including nausea and diarrhea, particularly with high doses of MCT oil or BHB salts. Ketone salts can also lead to a high mineral load, especially sodium.

Exogenous ketones, such as BHB salts and esters, can raise blood ketone levels within 30 to 60 minutes of consumption. MCT oil also provides a quick energy source, but the effect of raising ketone levels is more moderate than exogenous ketones.

Both can support weight loss by promoting ketosis and increasing satiety. MCT oil boosts fat intake and increases calorie expenditure, while exogenous ketones can reduce appetite. The 'best' choice depends on your specific needs, but neither is a magic pill for weight loss without dietary consistency.

Ketone esters are a more powerful, raw liquid form that provides a rapid and high increase in blood ketone levels, often for athletic performance. Ketone salts are a mineral-bound powder that is less potent but more palatable and affordable.

Yes, supplementing with electrolytes like sodium, potassium, and magnesium is highly recommended, especially when you first start. It helps counteract the mineral loss that occurs when transitioning to a low-carb diet and can prevent symptoms of the 'keto flu'.

References

  1. 1
  2. 2
  3. 3
  4. 4

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.