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What is the name of B12 and B9?

4 min read

According to the National Institutes of Health, vitamin B9 and vitamin B12 are critical for DNA synthesis and repair. You may know them by their numbered designations, but their formal chemical names are folate and cobalamin, respectively.

Quick Summary

Vitamin B9 is known as folate, or folic acid in its synthetic form, while vitamin B12 is called cobalamin. They are water-soluble B vitamins that play crucial roles in cell metabolism, DNA synthesis, and red blood cell formation.

Key Points

  • B12 Name: The scientific name for Vitamin B12 is cobalamin, which is unique among vitamins for containing the mineral cobalt.

  • B9 Name: Vitamin B9 is known as folate, the natural form, and folic acid, its synthetic form used in supplements and fortified foods.

  • Essential Functions: Both vitamins are vital for critical biological processes, including DNA synthesis, cell growth, and red blood cell production.

  • Dietary Sources: B9 (folate) is found in leafy greens and legumes, while B12 (cobalamin) is almost exclusively from animal products and fortified foods.

  • Deficiency Concerns: A deficiency in either can lead to megaloblastic anemia, while a B12 deficiency can also cause nerve damage.

  • Supplementation Considerations: High doses of synthetic folic acid can mask a B12 deficiency, so it's important to monitor both vitamin levels.

  • Unique Absorption: Unlike folate, B12 requires a protein called intrinsic factor for proper absorption in the body, which can be a concern for some individuals.

In This Article

Unpacking the Names: Folate (B9) and Cobalamin (B12)

Many people are familiar with the B vitamin family but may not know the specific names for each one. Understanding what is the name of B12 and B9, and their different forms, is the first step toward appreciating their unique roles in the body. While both are water-soluble and work together, they are distinct molecules with separate functions. Vitamin B9 is referred to as folate, a term that encompasses the naturally occurring form found in food, and folic acid, its synthetic counterpart used in supplements and fortified foods. Vitamin B12, on the other hand, is known as cobalamin, and it's the only vitamin that contains the mineral cobalt. This unique chemical structure explains why B12 is found almost exclusively in animal products.

The Importance of Folate (B9)

Folate is a critical nutrient for several key biological processes. Its name comes from the Latin word folium, meaning leaf, reflecting its natural abundance in leafy green vegetables. Folate is especially important for women of childbearing age because it plays a vital role in preventing neural tube defects in developing fetuses. Beyond pregnancy, it's essential for cell growth, DNA synthesis, and the formation of red blood cells. A deficiency can lead to anemia, as well as an increased risk of certain health issues. To get enough folate, you can consume leafy greens, legumes, and fortified grains.

The Role of Cobalamin (B12)

Cobalamin, or vitamin B12, is essential for maintaining nerve function, producing red blood cells, and synthesizing DNA. Unlike other B vitamins, B12 requires a special protein called intrinsic factor to be absorbed effectively in the stomach. Without sufficient intrinsic factor, a person can develop a B12 deficiency even if their diet includes enough B12. This is a common issue for older adults or those with certain autoimmune conditions. The body doesn't produce cobalamin, so it must be obtained from food sources, primarily animal products like meat, fish, eggs, and dairy. Vegans and vegetarians often need to rely on fortified foods or supplements to meet their B12 requirements.

Comparison of Folate and Cobalamin

Feature Vitamin B9 (Folate/Folic Acid) Vitamin B12 (Cobalamin)
Primary Function DNA synthesis, cell growth, red blood cell formation, neural tube development Nerve function, red blood cell formation, DNA synthesis, brain health
Natural Food Sources Leafy greens, legumes, asparagus, eggs Meat, fish, poultry, eggs, dairy, fortified foods
Absorbed Form Folate (natural) and Folic Acid (synthetic) Cobalamin (requires intrinsic factor for absorption)
Key Deficiency Symptom Anemia, birth defects (in deficiency during pregnancy) Anemia, nerve damage, cognitive issues
Risk of Deficiency Pregnant women, individuals with malabsorption disorders Vegans, vegetarians, older adults, individuals with pernicious anemia

The Synergy of B12 and B9

The interplay between folate and cobalamin is vital for several metabolic processes. They work together in the synthesis of methionine, an amino acid, and in regulating the levels of homocysteine. High homocysteine levels have been linked to an increased risk of cardiovascular disease and dementia. A deficiency in either B9 or B12 can cause a type of anemia called megaloblastic anemia, which results from impaired DNA synthesis. Interestingly, high levels of folic acid from supplements can mask a B12 deficiency, potentially allowing neurological damage to progress undetected. This is why it is important to test both vitamin levels when a deficiency is suspected.

Common Sources for Getting Your B Vitamins

Many foods are excellent sources of B vitamins. Here is a brief list of common examples:

  • For Folate (B9): Lentils, spinach, asparagus, chickpeas, and broccoli are all rich in this vitamin. Fortified breakfast cereals and enriched pasta also contain folic acid.
  • For Cobalamin (B12): This vitamin is found in abundance in animal products. Good sources include salmon, tuna, beef, milk, and eggs. Certain nutritional yeast products and fortified cereals are reliable sources for those on a plant-based diet.

Conclusion: More Than Just Numbers

Knowing what is the name of B12 and B9 gives you a clearer understanding of these two essential nutrients. Vitamin B9 is known as folate or folic acid, and B12 is called cobalamin. Though often grouped together, their distinct sources and absorption pathways highlight the importance of a balanced diet or, when necessary, appropriate supplementation. Their synergistic relationship is crucial for maintaining optimal cell health, preventing anemia, and supporting the nervous system, proving they are far more than just a pair of numbers in the B vitamin complex. For further information on the B vitamin family, the Harvard T.H. Chan School of Public Health's Nutrition Source website offers a wealth of detailed information.

Note: While supplements can help address deficiencies, it's always best to speak with a healthcare provider before starting any new regimen.

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The Importance of Folate (B9)

The Role of Cobalamin (B12)

Comparison of Folate and Cobalamin

The Synergy of B12 and B9

Common Sources for Getting Your B Vitamins

Conclusion: More Than Just Numbers

  • For Folate (B9): Lentils, spinach, asparagus, chickpeas, and broccoli are all rich in this vitamin. Fortified breakfast cereals and enriched pasta also contain folic acid.

  • For Cobalamin (B12): This vitamin is found in abundance in animal products. Good sources include salmon, tuna, beef, milk, and eggs. Certain nutritional yeast products and fortified cereals are reliable sources for those on a plant-based diet.

Frequently Asked Questions

The common name for Vitamin B12 is cobalamin, while Vitamin B9 is known as folate in its natural form and folic acid in its synthetic form.

B9 and B12 work in synergy to regulate homocysteine levels and aid in DNA metabolism and synthesis. A deficiency in either can disrupt this process and lead to health issues.

Foods rich in folate include leafy green vegetables like spinach, as well as legumes such as lentils and chickpeas. Many grain products in the United States are also fortified with folic acid.

Cobalamin is primarily found in animal products like meat, eggs, fish, and dairy. For those on a vegan or vegetarian diet, fortified cereals and nutritional yeast are key sources.

Deficiencies in either vitamin can result in megaloblastic anemia. A B12 deficiency can also lead to nerve damage and cognitive problems, while a B9 deficiency is a risk factor for neural tube defects in infants.

Folate is the form of B9 that occurs naturally in foods, while folic acid is the synthetic, supplemental form. Folic acid is generally better absorbed by the body than folate from food sources.

Yes, excessive folic acid intake can mask a vitamin B12 deficiency, potentially allowing neurological damage from the B12 deficiency to progress undetected.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.