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What is the Prolon 5-day reset and how does it work?

5 min read

Developed over two decades by researchers at the University of Southern California, the Prolon 5-day reset is a patented, plant-based program designed to induce the benefits of prolonged fasting while providing nourishment. This five-day program is scientifically formulated to help your body enter a rejuvenating state without fully abstaining from food.

Quick Summary

The Prolon 5-day fasting mimicking diet is a pre-packaged program providing low-calorie, plant-based meals that safely trigger cellular rejuvenation and fat-burning for overall health.

Key Points

  • Fasting Mimicking Diet (FMD): A five-day, low-calorie, plant-based program designed to trigger the benefits of prolonged fasting without abstaining entirely from food.

  • Cellular Rejuvenation: The program activates autophagy, a natural process of cellular clean-up and renewal, leading to the removal of damaged cells.

  • Weight and Metabolic Benefits: Users often experience fat-focused weight loss, particularly abdominal fat, while preserving lean muscle mass.

  • Convenience: The Prolon reset comes in a pre-packaged kit containing all necessary meals, snacks, and supplements for the five-day period.

  • Backed by Science: Developed through decades of research by Dr. Valter Longo at the USC Longevity Institute and patented for its healthy aging effects.

  • Gradual Progression: The five days build on each other, with specific metabolic changes like ketosis and autophagy kicking in over the course of the program.

  • Transition Day: A specific day after the 5-day cycle is recommended to reintroduce food gradually and maximize benefits.

In This Article

What is the Fasting Mimicking Diet (FMD)?

The Fasting Mimicking Diet (FMD) is a dietary approach that cycles between periods of eating and calorie restriction. Unlike traditional fasting, which involves consuming only water for an extended period, FMD provides a specific, low-calorie, plant-based diet for a limited number of days. The Prolon 5-day reset is the original, patented FMD, designed by Dr. Valter Longo and his team at the University of Southern California. The genius behind the program lies in its formulation: the foods included are precisely balanced to provide essential nutrients while being low enough in calories and specific macronutrients (like protein) to not trigger the body's nutrient-sensing pathways. This tricks the body into entering a fasting state, activating key cellular and metabolic processes typically associated with a longer water-only fast. The program is meant to be used for five consecutive days, followed by a transition day, before resuming a normal diet. This structured approach is designed to be safer and more manageable than a prolonged water-only fast, especially for those seeking to incorporate fasting into a regular health routine.

How Does the Prolon 5-day Reset Work?

The Prolon program works over a five-day period, with specific physiological changes occurring each day. The program relies on the body's natural processes of adaptation and repair, transitioning through different metabolic states:

  • Day 1: Transitioning to a Fasting State. On the first day, your body begins to adjust to the reduced calorie and glucose intake. Glucose stores diminish, and the body shifts toward fat-burning and prepares for cellular renewal.
  • Day 2: Fat Burning and Ketogenesis. By the second day, glucose stores are largely depleted, and the body switches to using fat reserves for fuel. This process, known as ketosis, intensifies as the body produces and utilizes ketones for energy.
  • Day 3: Cellular Clean-up (Autophagy). The program is formulated to trigger autophagy, a critical cellular process where the body recycles damaged and old cellular components to regenerate newer, healthier cells.
  • Day 4: Peak Cellular Rejuvenation. Autophagy is in full effect, and the cellular repair and renewal process intensifies. Fat-burning continues to provide a steady source of energy.
  • Day 5: Renewal and Re-feeding. The fasting period concludes, but the process of cellular reprogramming continues. The final day emphasizes the completion of the fast and preparing the body for a gentle transition back to a normal diet.

What's in a Prolon 5-day Kit?

Each Prolon kit contains a variety of pre-packaged, plant-based foods for each of the five days, removing the guesswork from fasting. The meals are designed for ease of use and to maximize the fasting-mimicking effect. Typical items found in a kit include:

  • Soups: Vegetable-based soups like minestrone, mushroom, tomato, and quinoa minestrone.
  • Snacks: Olives, kale crackers, and nut bars (such as almond or macadamia).
  • Drinks: Herbal teas and a fruit-flavored, proprietary glycerol drink called the L-Drink, designed to protect muscle mass.
  • Supplements: Vitamin and mineral supplements to ensure nutritional support during the reset.

Benefits of the Prolon 5-day Reset

The Prolon program is associated with several potential health benefits, backed by clinical studies.

Cellular Rejuvenation (Autophagy)

By inducing autophagy, the Prolon reset supports the body's natural process of intracellular clean-up, which is vital for cellular health and healthy aging. This process removes cellular waste and helps to rejuvenate cells.

Weight Loss and Metabolic Health

Clinical studies have shown that participants on the Prolon program experience fat-focused weight loss, particularly a reduction in abdominal fat, while preserving lean muscle mass. The program may also improve metabolic markers like blood sugar balance and insulin sensitivity.

Healthy Aging

The program is patented for its healthy aging effects, with research indicating that it supports the body's ability to promote longevity by influencing cellular aging pathways.

Improved Well-being

Many users report an improved sense of well-being, increased energy, and greater mental clarity following the reset. It can also help to establish a healthier relationship with food by reducing cravings and improving portion control.

Prolon vs. Traditional Fasting

Feature Prolon 5-Day Fasting Mimicking Diet (FMD) Traditional Prolonged Water Fasting
Convenience Pre-packaged kits remove guesswork; easy to follow. Requires significant planning and self-discipline; no pre-packaged meals.
Nutritional Support Provides essential plant-based nutrients, vitamins, and minerals. Consumes only water, potentially leading to nutrient deficiencies.
Metabolic Shift Calorie restriction triggers a fasting state while providing nourishment. Complete calorie deprivation forces the body into a fasting state.
Muscle Preservation Specifically designed to protect lean body mass during the fast. Higher risk of losing lean muscle mass alongside fat.
Side Effects Milder, though still possible, side effects like headaches or fatigue. Higher risk of severe side effects, dehydration, and nutrient imbalance.
Clinical Backing Developed with decades of research and clinical trials. Limited clinical research on long-term safety and efficacy.

What to Expect During the Reset

Your experience with the Prolon reset can vary, but there are some common patterns. You may feel a bit sluggish or have a headache on Day 2 or 3 as your body transitions into a fasting state. Energy levels often increase after this initial period. Staying hydrated with plenty of water and the provided herbal teas is crucial. Strenuous exercise is not recommended during the reset, but light activities like walking are generally fine. The last few days are typically when many people report clearer thinking and a better sense of well-being. The transition day (Day 6) is important for slowly reintroducing regular foods to your system to avoid digestive upset.

Conclusion

In essence, the Prolon 5-day reset offers a scientifically developed and clinically tested method to achieve the benefits of prolonged fasting without full food deprivation. By leveraging the power of a fasting mimicking diet, the program supports cellular rejuvenation, metabolic health, and weight loss. For those seeking a metabolic reset or to incorporate healthy aging practices into their routine, Prolon provides a structured and convenient approach. However, as with any significant dietary change, it is important to consult with a healthcare professional to ensure it is appropriate for your individual health circumstances, especially if you have pre-existing conditions or are on medication.

For more information on the science behind FMD, you can visit the official Prolon website. Prolonlife.com

Frequently Asked Questions

The primary purpose is to induce cellular rejuvenation and provide metabolic benefits associated with prolonged fasting, while still allowing you to consume a specially formulated, plant-based diet.

No. Unlike a water-only fast, the Prolon reset provides you with essential nutrients through a structured, low-calorie, plant-based meal plan. This helps reduce the risks and side effects associated with complete food deprivation.

It depends on your health goals. For general healthy aging, it is often recommended 2-3 times per year. For specific metabolic objectives, it might be suggested more frequently, but you should always consult a healthcare professional for guidance.

The kit contains a variety of pre-packaged, plant-based foods, including soups, nut bars, olives, kale crackers, herbal teas, supplements, and a glycerol drink.

Common side effects can include fatigue, headaches, dizziness, and difficulty concentrating, especially during the initial days. These are typically mild and tolerated by most people.

Prolon is not recommended for pregnant or breastfeeding women, people with certain medical conditions like diabetes (without doctor supervision), those with eating disorders, or individuals who are underweight.

Yes, it is important to follow the meal plan as instructed, including eating only the foods provided in the kit on the designated days. This ensures that the fasting-mimicking effect is achieved.

During the reset, you are advised to only drink water and the provided caffeine-free herbal teas. Other beverages, including coffee, can break the fast.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.