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Where Does Vitamin K2 Come From? Unpacking the Sources

5 min read

While vitamin K1 is abundant in leafy green vegetables, vitamin K2 is unique because it is predominantly synthesized by bacteria. This makes its primary sources fermented foods and animal products, a key distinction from other vitamins. Understanding where this vital nutrient originates is crucial for ensuring adequate intake for optimal bone and heart health.

Quick Summary

Vitamin K2, or menaquinone, is mainly sourced from bacterial synthesis in fermented foods and some animal products. Unlike plant-based vitamin K1, K2 is less common in the modern diet but vital for calcium metabolism and bone health.

Key Points

  • Microbial Synthesis: Vitamin K2 is produced by bacteria through fermentation or within animal guts, distinguishing it from plant-derived vitamin K1.

  • Rich Sources: Natto is the most concentrated dietary source, while other fermented foods like cheese and sauerkraut also contain K2.

  • Animal Products: Organ meats, egg yolks, and dairy from grass-fed animals are good sources of the MK-4 subtype of vitamin K2.

  • Absorption Advantage: Vitamin K2 is absorbed more efficiently and remains in the body longer than K1, allowing for better delivery to tissues like bones and arteries.

  • Gut Contribution: Our gut bacteria can produce K2, but dietary intake is still essential for meeting nutritional needs.

  • Critical Function: K2 plays a key role in calcium metabolism, directing it away from arteries and into bones, supporting both cardiovascular and skeletal health.

In This Article

The Microbial Origin of Vitamin K2

Contrary to most vitamins, which are readily available in fresh plant sources, vitamin K2 is a product of bacterial activity. This microbial synthesis is what defines its distribution in food. The family of vitamin K2 compounds, known as menaquinones (MKs), have subtypes (e.g., MK-4, MK-7) whose presence varies based on the specific bacteria involved in fermentation and the animal's diet.

Fermented Foods: The Richest Sources

The fermentation process, in which bacteria break down substances, creates some of the most potent food sources of vitamin K2.

  • Natto: This traditional Japanese dish of fermented soybeans is, by far, the highest natural source of vitamin K2, particularly the MK-7 subtype. The Bacillus subtilis natto bacteria are responsible for this impressive synthesis. A single ounce can provide several times the recommended daily intake of total vitamin K.
  • Cheeses: Certain types of cheese, especially hard and aged varieties like Gouda, Edam, and some soft cheeses like Brie, contain notable amounts of K2. The specific bacterial cultures used in the ripening process contribute significantly to the final K2 content.
  • Sauerkraut: This fermented cabbage product is a good source of vitamin K2, though it provides much lower amounts than natto. Like other fermented foods, its K2 content is a result of the bacterial fermentation.
  • Kefir: A fermented dairy drink, kefir also contains vitamin K2 due to the bacteria and yeast used in its production.

Animal Products: From Diet to Tissue

In animals, vitamin K2 (specifically the MK-4 subtype) is concentrated in the liver and other fatty tissues. The animal's diet can influence the level of K2 present.

  • Organ Meats: Liver from beef, chicken, and goose is a particularly concentrated source of MK-4.
  • Egg Yolks: Eggs, especially from free-range chickens, contain moderate amounts of vitamin K2.
  • Grass-Fed Butter and Dairy: Dairy products from grass-fed animals tend to have higher levels of vitamin K2 (MK-4) than those from grain-fed animals.
  • Meat: The meat of animals, particularly darker meats and liver, contains vitamin K2.

The Role of Our Own Gut Bacteria

Our own intestinal microbiota can synthesize various forms of menaquinones (K2) in the large intestine. While this internal production contributes to our overall vitamin K status, the amount is often not enough to meet all of our body's requirements, making dietary sources crucial. This process is highly dependent on the balance of bacteria in our gut, emphasizing the importance of overall digestive health.

The Difference Between Vitamin K1 and K2

Understanding the distinction between vitamin K1 and K2 is essential for addressing dietary needs. K1 is predominantly involved in blood clotting and is quickly used by the liver. K2, with its longer side chain and half-life, is more readily distributed to extra-hepatic tissues like bones and arteries, where it activates proteins vital for calcium utilization.

Feature Vitamin K1 (Phylloquinone) Vitamin K2 (Menaquinone)
Primary Source Green leafy vegetables, plant oils Fermented foods, animal products
Producer Plants, associated with photosynthesis Bacteria (in fermented foods and gut), animal tissue
Body Function Primarily blood clotting in the liver Primarily directs calcium to bones and away from arteries
Absorption Poorly absorbed from plants Better absorbed, especially from fatty foods
Half-Life Short, cleared from the blood quickly Longer, circulates in the blood for days

The Importance of Variety for Optimal Intake

To ensure a comprehensive intake of vitamin K2, a varied diet is recommended. For instance, while natto is an excellent source of MK-7, animal products provide the MK-4 subtype. These different forms may have distinct, though complementary, functions in the body. Combining sources is an effective strategy. For example, enjoying a cheese plate with aged Gouda and some pâté can cover multiple bases. For those who find natto's taste challenging, supplements offer a reliable way to ensure a consistent intake of high-quality, naturally fermented MK-7. Individuals on blood-thinning medication should consult a healthcare professional before significantly altering their vitamin K intake.

Conclusion

Vitamin K2 is a fat-soluble vitamin primarily sourced from bacterially-driven processes, namely fermentation and synthesis within animal tissues. This origin sets it apart from its leafy-green counterpart, vitamin K1, and explains its concentration in unique food items like natto, hard cheeses, and organ meats. While our gut bacteria contribute to our K2 levels, relying on a diverse range of dietary sources is the most reliable way to secure an adequate supply of this crucial nutrient. By incorporating a variety of fermented foods and certain animal products into your diet, you can support essential bodily functions, including proper calcium metabolism for bone and cardiovascular health.

Potential Outbound Link

For a deeper scientific dive into the biological mechanisms of Vitamin K, including its subtypes and functions, an excellent resource can be found on the National Institutes of Health website. https://ods.od.nih.gov/factsheets/VitaminK-HealthProfessional/

Key Takeaways

  • Bacterial Origin: Vitamin K2 is unique because it is primarily created by bacteria, found in fermented foods and synthesized in animals.
  • Top Food Sources: Natto is the richest source of K2 (MK-7), while cheese and organ meats are also significant contributors.
  • K1 vs. K2: K2 has a longer half-life and is better absorbed than K1, allowing it to benefit tissues beyond the liver, such as bones and arteries.
  • Animal Diet Matters: The vitamin K2 (MK-4) content in animal products like meat, eggs, and dairy can be influenced by the animal's diet, with grass-fed animals often yielding higher levels.
  • Supplements are an Option: Given the scarcity of rich K2 sources in a typical Western diet, supplements, especially with the MK-7 subtype, are a viable option for many.
  • Health Benefits: K2 is crucial for directing calcium, promoting proper bone mineralization and preventing arterial calcification, thus supporting bone and cardiovascular health.

FAQs

Question: What is the difference between vitamin K1 and K2? Answer: Vitamin K1 (phylloquinone) comes from plants and is primarily involved in blood clotting. Vitamin K2 (menaquinone) is produced by bacteria, found in fermented and animal foods, and is vital for directing calcium to bones and arteries.

Question: Is it possible to get enough vitamin K2 from my gut bacteria alone? Answer: While gut bacteria do produce some vitamin K2, the amount is often insufficient to meet the body's optimal needs. Diet remains the most reliable source for a substantial intake.

Question: Why are fermented foods like natto so high in vitamin K2? Answer: The high concentration of vitamin K2 in natto is due to the specific bacterium Bacillus subtilis natto used in its fermentation process, which is a powerful K2 synthesizer.

Question: Does the vitamin K2 content vary in cheeses? Answer: Yes, the amount of vitamin K2 in cheese can vary based on the type, aging process, and the specific bacterial cultures used during production.

Question: Are grass-fed animal products really higher in vitamin K2? Answer: Animal products from grass-fed animals are often higher in vitamin K2 (MK-4) because the animals consume more K1 from green grass, which is then converted and stored.

Question: Should I take a vitamin K2 supplement? Answer: Given that many people do not consume enough K2-rich foods, supplements are a popular option. It's best to consult a healthcare provider to determine if supplementation is right for you, especially if you are on blood-thinning medication.

Question: How does vitamin K2 contribute to bone health? Answer: Vitamin K2 activates proteins, like osteocalcin, that regulate calcium usage in the body. This process helps incorporate calcium into bones, improving bone density and strength.

Frequently Asked Questions

Vitamin K1 comes from plants and is mainly for blood clotting. Vitamin K2 is made by bacteria, found in fermented/animal foods, and helps guide calcium to bones.

Natto is exceptionally high in K2 because it is fermented with Bacillus subtilis natto, a bacterium known for producing large amounts of the MK-7 subtype of vitamin K2.

Yes, the level of vitamin K2 in cheese depends on the type of cheese, the aging process, and the specific bacteria used during fermentation.

Products from grass-fed animals, such as dairy and butter, generally have higher levels of vitamin K2 (MK-4) because the animals convert the K1 from their green diet into K2.

While our gut bacteria contribute to our K2 supply, the amount is usually not sufficient to meet all our needs, making dietary intake crucial.

Vitamin K2 activates proteins that help regulate calcium metabolism. By directing calcium towards the bones, it helps improve bone density and reduce fracture risk.

MK-4 is a specific subtype of vitamin K2 found primarily in animal products like liver and eggs. It is formed in animals from the conversion of vitamin K1.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.