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Where is Ergocalciferol Obtained From?

3 min read

According to the National Institutes of Health, fortified foods provide the majority of vitamin D in American diets. Ergocalciferol, also known as vitamin D2, is a fat-soluble vitamin primarily sourced from plants and fungi when they are exposed to ultraviolet (UV) light. This makes it a crucial form of the vitamin for individuals following a vegan or plant-based diet.

Quick Summary

Ergocalciferol (vitamin D2) is derived from plant and fungal sources, notably UV-exposed mushrooms and yeast, in contrast to animal-derived vitamin D3. It is also a key additive in many fortified foods, providing an important dietary source for vitamin D.

Key Points

  • Plant-Based Source: Ergocalciferol (vitamin D2) is derived from plants and fungi, making it a key vitamin D source for vegans and vegetarians.

  • UV Exposure is Key: The vitamin D2 in plants and fungi like mushrooms is generated when they are exposed to ultraviolet (UV) light.

  • Fortified Foods: Many common foods, including plant-based milks, cereals, and orange juice, are fortified with ergocalciferol.

  • Supplements are Common: Manufactured ergocalciferol supplements are widely available and used to prevent and treat vitamin D deficiency.

  • Compare to D3: Ergocalciferol (D2) comes from plant sources, while cholecalciferol (D3) comes from animal sources and sun exposure.

  • For Deficiency Treatment: Ergocalciferol is prescribed to treat conditions like hypoparathyroidism and rickets.

In This Article

Ergocalciferol's Plant and Fungal Origins

Ergocalciferol (vitamin D2) is naturally produced by some plants and fungi when a compound called ergosterol is exposed to ultraviolet-B (UVB) light. This process is analogous to how human skin produces vitamin D3 upon sun exposure, making ergocalciferol a reliable plant-based vitamin D source. The most well-known natural food sources are specific types of mushrooms that have been exposed to UV light, which significantly increases their vitamin D2 content.

UV-Treated Mushrooms

Mushrooms are the most common natural food source of ergocalciferol. The vitamin D content varies greatly depending on whether they have been commercially treated with UV light or grown in natural sunlight. Wild mushrooms generally have higher vitamin D levels than cultivated ones, but commercial growers can now use UV lamps to boost the vitamin D2 levels in their mushrooms significantly.

  • Crimini mushrooms: Raw crimini mushrooms can contain high levels of D2 when exposed to UV light.
  • Portobello mushrooms: Like crimini, the D2 content of portobello mushrooms is greatly enhanced through UV exposure.
  • Shiitake mushrooms: Both raw and dried shiitake mushrooms are also known sources, with dried varieties containing more D2 naturally.

Yeast and Algae

Yeast is another primary source, particularly in the production of dietary supplements. When yeast is exposed to UV irradiation, it generates ergocalciferol, which can then be isolated and used to fortify foods or produce supplements. Some types of algae may also contain vitamin D2.

Fortified Foods as a Major Source

For many, especially those in regions with limited sunlight or following specific diets, fortified foods provide a significant portion of their ergocalciferol intake. Manufacturers add vitamin D2 to various products to help consumers meet their daily requirements.

  • Plant-based milks: Soy milk, almond milk, and oat milk are frequently fortified with ergocalciferol to provide a vitamin D source for vegan consumers.
  • Breakfast cereals: Many ready-to-eat cereals include added vitamin D2.
  • Orange juice: Some brands of orange juice are fortified with vitamin D.
  • Margarine: Certain margarines and fat spreads are enhanced with ergocalciferol.

Dietary Supplements

Beyond whole foods, ergocalciferol is widely available in supplement form for treating or preventing vitamin D deficiency. Supplements are a reliable way to ensure adequate intake, particularly for those with absorption issues or high deficiency risk. Ergocalciferol supplements are manufactured in laboratories by irradiating yeast-derived ergosterol.

Comparison: Ergocalciferol (D2) vs. Cholecalciferol (D3)

Ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3) are the two main forms of vitamin D, but they differ in origin and potentially in effectiveness. While both help the body absorb calcium and phosphorus, research suggests D3 may be more effective at raising and maintaining overall vitamin D blood levels, though both can treat deficiency.

Feature Ergocalciferol (Vitamin D2) Cholecalciferol (Vitamin D3)
Source Plants and fungi (e.g., mushrooms, yeast) when exposed to UV light. Animals (e.g., fatty fish, egg yolks) and produced in skin upon sun exposure.
Vegan-Friendly Yes, derived from non-animal sources. Typically not, though some vegan D3 from lichen is available.
Fortified Foods Often used in fortified cereals, plant milks, and juices due to lower cost. Less common in fortified products but sometimes used.
Potency Some evidence suggests it may be less potent and shorter-acting than D3 in raising blood levels. Often considered more potent and effective at maintaining blood levels.

Who Should Consider Ergocalciferol?

While ergocalciferol is used to treat vitamin D deficiency, its plant-based origin makes it particularly suitable for certain individuals.

  • Vegans and Vegetarians: Since D2 is sourced from plants and fungi, it is a primary option for those who do not consume animal products.
  • Those with Malabsorption: People with conditions that impair nutrient absorption may be prescribed high-dose ergocalciferol.
  • Patients with Specific Conditions: MedlinePlus notes its use in treating hypoparathyroidism, refractory rickets, and familial hypophosphatemia.

For most people, a combination of sun exposure, diet, and potentially supplements is needed to maintain sufficient vitamin D levels. You can learn more about vitamin D and its forms from the National Institutes of Health's Office of Dietary Supplements.

Conclusion

Ergocalciferol, or vitamin D2, is primarily obtained from plant-based and fungal sources that have been exposed to ultraviolet light. Key sources include UV-treated mushrooms and yeast. It is also a common ingredient in fortified foods such as plant-based milks, cereals, and orange juice. While some evidence suggests cholecalciferol (D3) may be more potent, ergocalciferol remains a vital nutrient, especially for those adhering to a vegan lifestyle. Whether through diet, fortified products, or supplements, understanding the different sources of this essential vitamin is crucial for maintaining overall bone and immune health.

Frequently Asked Questions

The primary difference lies in their source: D2 is obtained from plant and fungal sources exposed to UV light, whereas D3 is from animal sources or human skin exposed to sunlight.

Mushrooms like crimini, portobello, and shiitake are known sources, particularly when they have been purposely exposed to UV light to boost their vitamin D2 content.

Yes, ergocalciferol is used to prevent and treat vitamin D deficiency and has similar efficacy to cholecalciferol, though some studies suggest D3 may be more potent.

Common fortified foods include some plant-based milks (soy, almond), breakfast cereals, certain brands of orange juice, and margarine.

Yes, vegans can get vitamin D from ergocalciferol. It is one of the few readily available vegan food sources of vitamin D, along with fortified products and some lichen-derived D3.

Ergocalciferol is sometimes used in supplements because it is cheaper to produce than D3 and is a suitable plant-based option. It can also be formulated in high doses for prescription use.

Ergocalciferol (D2) is formed when UV light hits ergosterol in plants, while the vitamin D produced by human skin (D3) is formed when UV light hits a different compound called 7-dehydrocholesterol.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.