The Unique Strain: Bifidobacterium infantis 35624
For those seeking targeted relief for digestive issues, understanding the specific probiotic strain is crucial. The strain in question, Bifidobacterium infantis 35624, has a notable history and is backed by extensive scientific research. Originally classified as Bifidobacterium infantis 35624, it was reclassified as a subspecies of Bifidobacterium longum, now known as Bifidobacterium longum subsp. longum 35624. It is also known by the patented trademark Bifantis™. Despite the scientific name change, many products and studies still refer to it by its original name.
This particular strain was isolated directly from the gut of a healthy human subject. Unlike many generic probiotics, the 35624 strain has been the focus of multiple randomized, placebo-controlled clinical trials to investigate its effects, particularly on gastrointestinal health. The fact that it is a patented strain means its efficacy and stability have been rigorously tested and documented, setting it apart from non-specified bacterial strains often found in lower-cost supplements.
Where to Find the Bifidobacterium infantis 35624 Probiotic
If you are looking for a probiotic containing this specific strain, the brand you need to look for depends on your geographic location. The manufacturer has different brand names for different markets:
- Align® Probiotics (North America): In the United States and Canada, the 35624 strain is marketed under the brand name Align. It is a daily dietary supplement available in various formats, including capsules and gummies. Align's packaging is specifically designed to ensure the bacteria remain viable and effective until the expiration date.
- Alflorex® (Europe and other regions): Outside of North America, the same patented strain is sold under the brand name Alflorex. This product is widely available in Europe, Ireland, the UK, and other parts of the world. Alflorex capsules contain the same unique 35624 strain.
Are Align and Alflorex the same?
Yes, for all intents and purposes, they contain the same key ingredient. The core formulation containing the Bifidobacterium longum subsp. longum 35624 strain is consistent across both brands. The difference lies mainly in the branding and regional marketing. For consumers seeking this specific strain, both products are equivalent in their active probiotic component.
Clinically Researched Benefits of B. infantis 35624
The extensive research behind the 35624 strain has highlighted several significant health benefits, especially concerning digestive and immune function.
Relief for Irritable Bowel Syndrome (IBS) Symptoms
One of the most well-documented uses for this strain is the management of Irritable Bowel Syndrome (IBS) symptoms. Clinical trials have demonstrated that daily use of the 35624 strain can provide ongoing relief from common IBS symptoms.
- Reduces abdominal pain and discomfort.
- Alleviates bloating and gas.
- Improves bowel habit satisfaction.
Research has shown significant reductions in the overall severity of IBS symptoms, with high patient response rates observed in some studies. The strain's efficacy appears to extend across different IBS subtypes, suggesting broad applicability.
Anti-Inflammatory Effects
The 35624 strain has also been shown to modulate the immune system and exert anti-inflammatory effects.
- Reduces Pro-Inflammatory Biomarkers: Studies have demonstrated that supplementation with the strain can reduce plasma levels of C-reactive protein (CRP), tumor necrosis factor α (TNF-α), and interleukin-6 (IL-6) in patients with various inflammatory conditions.
- Systemic Influence: The anti-inflammatory effects are not limited to the gut but can also be seen systemically, impacting extra-intestinal inflammatory conditions like chronic fatigue syndrome and psoriasis. This highlights the potential of gut-directed probiotics to influence overall health beyond the digestive tract.
A Comparison of Probiotic Options for Gut Health
When considering a probiotic for digestive support, it is helpful to compare the features of a targeted, single-strain product like Align with other alternatives. The right choice often depends on your specific health goals.
| Feature | Align (35624 Strain) | Alflorex (35624 Strain) | Generic Multi-Strain Probiotic |
|---|---|---|---|
| Primary Strain | Bifidobacterium longum subsp. longum 35624 | Bifidobacterium longum subsp. longum 35624 | Often a mix of various Lactobacillus and Bifidobacterium strains |
| Key Benefit | Targeted relief for IBS symptoms, including bloating, gas, and abdominal discomfort. | Same as Align; targeted relief for IBS and digestive support. | General gut health support; potential for specific benefits depending on strains included. |
| Research | Supported by extensive clinical research specifically on the 35624 strain. | Same as Align; research is specific to the 35624 strain. | Varies widely; dependent on the specific strains and dosages used. |
| Main Market | North America (USA, Canada) | Europe, Ireland, UK, and other regions | Worldwide (can vary significantly by brand) |
| Formulation | Often contains a single, patented probiotic strain for targeted action. | Patented single-strain formulation for precision. | Can contain a wide variety of strains, some with less specific research. |
| Cost | Considered relatively expensive compared to many other brands. | Can be perceived as expensive due to the patented, researched strain. | Typically more affordable, but quality and efficacy can vary. |
Who Should Consider a Probiotic with B. infantis 35624?
The 35624 strain is particularly beneficial for a few specific groups:
- Individuals with IBS: For those suffering from ongoing symptoms like abdominal pain, bloating, and gas, this strain is a top recommendation from many gastroenterologists due to its proven efficacy.
- People with Occasional Digestive Upsets: Even if you don't have an IBS diagnosis, this strain can help soothe occasional bloating and discomfort by promoting a healthy digestive balance.
- Those Seeking a Targeted Approach: If you have tried generic multi-strain probiotics without success and want a clinically-backed option, the single-strain focus of Align or Alflorex may be a better fit.
- Individuals with Inflammatory Conditions: Given the strain's documented anti-inflammatory properties, those with certain systemic inflammatory disorders may also benefit.
Considerations and Potential Side Effects
While generally safe for most people, there are a few important points to consider when taking a probiotic containing the 35624 strain.
- Possible Side Effects: Some users may experience minor side effects, such as initial gas or bloating, as their body adjusts to the new bacterial cultures. These effects are usually temporary.
- Consistent Daily Use: The benefits of the 35624 strain are sustained with consistent daily use. Studies show that when supplementation stops, symptoms may return, indicating that continuous intake is key for long-term effects.
- Antibiotic Interactions: If you are taking antibiotics, it is best to take probiotics at least 2-3 hours before or after your antibiotic dose to ensure the live bacteria are not killed.
- Immune-Compromised Individuals: Those with compromised immune systems should consult a doctor before starting any probiotic supplement.
Conclusion
The probiotic strain Bifidobacterium infantis 35624 is not available in generic or store-brand products, but rather exclusively in the branded supplements Align (North America) and Alflorex (Europe). This patented and well-researched strain offers targeted and clinically proven relief for Irritable Bowel Syndrome symptoms such as abdominal pain, gas, and bloating. Its documented ability to modulate the immune system and reduce inflammation provides additional systemic benefits beyond simple digestive support. When choosing a probiotic, opting for one with a specific, well-researched strain like the 35624 can ensure you receive the targeted benefits your body needs.
