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Which probiotic has Lactobacillus rhamnosus GG and Saccharomyces boulardii?

4 min read

According to a study published in 2021 in the journal Microorganisms, the combined supplementation of Lactobacillus rhamnosus GG and Saccharomyces boulardii showed a promising effect in limiting detrimental effects of antibiotics on the gut microbiome [1]. This powerful combination of a beneficial bacterium and a probiotic yeast is highly sought after by those seeking to restore gut flora, and several supplements contain both.

Quick Summary

Several multi-strain probiotic supplements contain both Lactobacillus rhamnosus GG (LGG) and Saccharomyces boulardii. This combination is effective for restoring gut flora, managing antibiotic-associated diarrhea, and supporting overall digestive health. Consumers should carefully check product labels for specific strain identification and CFU counts.

Key Points

  • Identify Specific Strains: Carefully check product labels to confirm the presence of both Lactobacillus rhamnosus GG and Saccharomyces boulardii with their specific identifiers [3].

  • Verify CFU Counts: Examine the Colony Forming Unit (CFU) count, ideally looking for the amount of each specific strain if possible.

  • Evaluate Delivery Methods: Consider if the product uses delayed-release capsules or other methods to ensure the probiotics survive stomach acid [3].

  • Recognize Diarrhea Benefits: This combination is particularly noted for its potential in managing antibiotic-associated and traveler's diarrhea [1].

  • Understand Strain Specificity: The health benefits of probiotics are strain-specific, so the exact strains used in a product are crucial [3].

  • Consult Healthcare Professionals: Seek advice from a doctor or dietitian to determine the best probiotic for your individual health needs.

In This Article

The Synergistic Duo: Lactobacillus rhamnosus GG and Saccharomyces boulardii

When seeking a potent probiotic blend, the combination of Lactobacillus rhamnosus GG (LGG) and Saccharomyces boulardii stands out for its well-researched benefits, especially in managing digestive disturbances. LGG is a specific bacterial strain known for its robust survivability through the gastrointestinal tract, its ability to adhere to the intestinal lining, and its positive impact on immune response [1, 2]. Saccharomyces boulardii, on the other hand, is a unique, beneficial yeast that is not affected by antibiotics, making it particularly effective for antibiotic-associated diarrhea [1]. Together, they offer a multi-faceted approach to restoring and maintaining gut health.

Finding Products Containing Both LGG and S. boulardii

While LGG and S. boulardii are often sold as single-strain supplements, several manufacturers have created multi-strain formulas to harness their combined power. Identifying which specific products contain both strains requires careful review of product labels. Probiotic supplements are available from various brands and can often be found in health food stores, pharmacies, and online retailers. The availability of these specific combination products can vary by country and region, so it's always best to check the product label carefully for the specific strains included.

What to Look for in a Combined Probiotic

Choosing the right probiotic requires more than just confirming the presence of the desired strains. Several factors determine a product's effectiveness:

  1. Strain Identification: Always look for products that specify the exact strain, such as Lactobacillus rhamnosus GG or Saccharomyces boulardii CNCM I-745, on the label [3]. Specificity is key, as benefits are strain-dependent.
  2. CFU Count: The Colony Forming Unit (CFU) count indicates the number of live microorganisms. While higher isn't always better, a dose of at least 1 billion CFU per day for clinically studied strains is often recommended [3].
  3. Delivery System: Probiotics must survive the harsh stomach environment. Look for delayed-release capsules or other protective technologies that ensure the organisms reach the intestines intact [3]. S. boulardii is naturally robust, but LGG needs protection.
  4. Stability and Storage: Some probiotics require refrigeration to maintain viability. Shelf-stable options, like many sachet and capsule forms, are more convenient, especially for travel.
  5. Clinical Evidence: Prioritize products that reference scientific studies supporting the health claims of their specific strains [3].

Comparative Considerations: LGG and S. boulardii Supplements

When comparing different products that may contain both LGG and S. boulardii, consider these aspects:

Feature Consideration
Included Strains Check for the specific strains L. rhamnosus GG and S. boulardii listed on the label. Some products may list the genus and species but not the specific strain identifier.
CFU Count Compare the stated CFU count, focusing on the number of each specific strain if provided. The total CFU count may not reflect the amount of the desired strains.
Format Available in various forms like capsules, sachets, or powders. Choose a format that is convenient for you and suits your needs.
Target Condition Some products may be formulated for specific digestive issues like antibiotic-associated diarrhea or general gut health.
Additional Ingredients Some supplements may include prebiotics or other complementary ingredients.

Conclusion

Finding a probiotic with both Lactobacillus rhamnosus GG and Saccharomyces boulardii is achievable by carefully examining product labels. This combination is supported by research for its potential benefits in managing digestive health. When making your selection, always scrutinize the label for specific strains and CFU counts, consider the delivery system, and check stability requirements. A doctor or dietitian can help you determine the best option for your individual needs, especially when addressing specific conditions like antibiotic-associated diarrhea or IBS. The robust clinical evidence supporting the individual strains within this duo makes it a reliable choice for effective gut health support.

Lists and Further Considerations

In addition to the comparative considerations, here are some points to remember:

  • Antibiotic-Associated Diarrhea: This specific combination, particularly S. boulardii, is effective for preventing and treating AAD because the yeast is not affected by antibiotics, allowing it to maintain gut flora balance during treatment [1].
  • Traveler's Diarrhea: Both LGG and S. boulardii have clinical support for reducing the incidence and duration of traveler's diarrhea, making a combination supplement a potential travel essential.
  • Delivery Form: Different delivery forms (capsules, sachets) cater to different preferences. Capsules offer convenience, while sachets can be mixed with food or beverages for easier consumption.
  • Potency: While the total CFU might seem impressive, look at the contribution of each specific strain. A product with a high total CFU count but low levels of LGG or S. boulardii might not deliver the desired therapeutic effect.

For more detailed information on probiotic strain specificity, consider researching reputable sources like the International Scientific Association for Probiotics and Prebiotics (ISAPP) or peer-reviewed journals [3].

Frequently Asked Questions

Identifying specific brands requires checking product labels as formulations change and vary by region. Look for multi-strain probiotic supplements that explicitly list both Lactobacillus rhamnosus GG and Saccharomyces boulardii on the ingredients list.

This combination is beneficial because it brings together a potent bacterial strain (LGG) and a robust yeast strain (S. boulardii). They are often studied for their potential to support gut flora balance, manage certain types of diarrhea, and contribute to digestive and immune health [1, 2].

Yes, S. boulardii is a yeast that is not affected by antibiotics, making it a suitable choice for use during antibiotic treatment. It is generally recommended to take probiotics a few hours apart from antibiotics [1].

Probiotics containing these strains are generally considered safe. Some individuals may experience mild, temporary digestive discomfort such as gas or bloating as their system adjusts. If you have concerns, consult a healthcare provider.

Storage instructions depend on the specific product. Some formulations are shelf-stable, while others, particularly those with live bacterial strains like LGG, may require refrigeration to maintain viability. Always follow the storage instructions on the product label.

The duration of probiotic supplementation varies depending on the intended use and individual health status. For acute conditions like diarrhea, a shorter course may be sufficient, while for general gut health support, longer-term use might be considered. Consult a healthcare professional for personalized guidance.

Not necessarily. The effectiveness of a probiotic is more dependent on the specific strains included and their documented benefits than solely on a high total CFU count. Ensure the product contains clinically relevant amounts of the desired strains, like LGG and S. boulardii [3].

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.