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Which Toxin is Found in Apples? The Truth About Cyanide in Apple Seeds

4 min read

While an apple a day is praised for health benefits, the seeds contain a compound called amygdalin. This leads to the question of which toxin is found in apples? This article explores the science behind the potential for cyanide release from apple seeds and the minimal risk it poses to human health.

Quick Summary

Apple seeds contain amygdalin, a compound that releases toxic hydrogen cyanide when chewed or crushed. Swallowing small, whole seeds is harmless, but consuming large quantities of crushed seeds could be dangerous.

Key Points

  • Amygdalin in seeds: Apple seeds contain a compound called amygdalin, which is a cyanogenic glycoside.

  • Cyanide release: Amygdalin can release toxic hydrogen cyanide only when the seeds are chewed or crushed, not when swallowed whole.

  • Toxicity threshold: A very large number of crushed seeds would need to be consumed to cause acute cyanide poisoning, making accidental poisoning highly unlikely.

  • Patulin in decay: An unrelated mycotoxin called patulin can form on apples that are moldy or rotten, and is a concern for juice products.

  • Low risk to humans: Standard consumption of fresh apple fruit is safe; simply avoid eating or crushing the seeds.

  • Other fruits with amygdalin: Seeds and pits of related fruits like cherries, apricots, and peaches also contain amygdalin.

In This Article

The Toxin in Apple Seeds: Amygdalin

For generations, people have been warned to avoid eating apple seeds, often citing concerns about poisoning. The source of this apprehension is a naturally occurring compound called amygdalin, which is a cyanogenic glycoside. Amygdalin is a substance that contains sugar and a cyanide component. It is present not only in apple seeds but also in the pits and kernels of other fruits belonging to the Rosaceae family, including peaches, apricots, cherries, and plums. The compound is safely encased within the hard outer shell of the seed, designed by nature to protect it from the digestive tracts of animals.

How Amygdalin Releases Cyanide

The crucial factor in the toxicity of amygdalin is its release from the protective seed coat. If a person swallows a few whole apple seeds, they will likely pass through the digestive system completely undigested, and the body will not absorb any toxins. However, if the seeds are crushed or chewed, the amygdalin is exposed to the body's digestive enzymes. This reaction can break down the amygdalin and release hydrogen cyanide (HCN), a highly poisonous gas. Cyanide works by interfering with the body's ability to use oxygen, which can cause severe damage to the heart and brain in high doses.

The Real Risk of Cyanide Poisoning

While the science is clear that crushed apple seeds can produce cyanide, the actual risk of poisoning is extremely low. For a lethal dose of cyanide, an adult would need to consume and thoroughly chew a significant number of seeds. Estimates vary depending on the specific apple variety and individual body weight, but one analysis suggests a person would need to ingest between 83 and 500 crushed seeds for acute poisoning. An average apple contains only a handful of seeds, meaning a single core holds nowhere near enough to cause harm. In practice, accidentally eating a few seeds while consuming an apple presents no significant risk to a healthy adult.

Cyanogenic Glycosides in Other Common Foods

Apple seeds are not the only source of cyanide-producing compounds in the plant world. The presence of cyanogenic glycosides is a common defense mechanism for many plant species.

  • Apricot Kernels: These have a notoriously high amygdalin content, and some health organizations explicitly warn against eating them.
  • Bitter Almonds: The wild, bitter variety of almonds contains a significant amount of amygdalin, unlike the sweet almonds sold for consumption.
  • Cherries, Peaches, and Plums: The pits of these stone fruits also contain amygdalin.
  • Flaxseeds: These seeds also contain cyanogenic compounds, though typically in amounts deemed safe for consumption.
  • Cassava: This root vegetable contains cyanogenic glycosides and requires extensive processing to be made safe for eating.

Other Toxins: The Case of Patulin in Moldy Apples

It is important to differentiate between the toxin in apple seeds and another potential hazard: patulin. Patulin is a mycotoxin, a toxic substance produced by fungi. It is not a natural component of healthy apples but can develop on fruit that is moldy, bruised, or rotten. The most common fungus responsible for patulin production is Penicillium expansum, which causes blue mold decay.

Patulin contamination is a concern primarily in apple products like juice and cider, which are often made from lower-grade or stored apples. Processing methods, such as heat treatment, can reduce the patulin levels, but not entirely eliminate them. Regulatory bodies have set limits on patulin levels in apple products to ensure consumer safety, with stricter limits for products intended for infants and young children. This is why sorting out damaged or rotten apples is a critical step in producing safe apple products.

Comparison of Apple Toxins

Feature Amygdalin (in Seeds) Patulin (in Moldy Fruit)
Source Naturally present in the kernels of apple seeds. A mycotoxin produced by fungi (e.g., Penicillium expansum) in decaying apples.
Toxic Agent Hydrogen Cyanide, released when seeds are chewed or crushed. Patulin, a heat-stable mycotoxin that contaminates rotting fruit.
Risk Factor Low risk for accidental ingestion of whole seeds; dangerous only in large, crushed quantities. Risk occurs from consuming moldy apples or apple products made from contaminated fruit.
Symptoms Cyanide poisoning symptoms (headaches, dizziness, nausea, low blood pressure). Linked to genotoxic and immunotoxic effects in high doses.
Mitigation Avoid chewing or crushing seeds. Swallowing a few whole seeds is not a concern. Avoid eating bruised or rotten apples. Proper fruit sorting and food processing are essential.

Preventing Exposure to Apple Toxins

For the average person enjoying a fresh apple, there is virtually no risk from amygdalin. The hard coating of the seeds is a very effective protective barrier. The simplest prevention method is to simply discard the apple core, as most people already do. When making homemade juice or smoothies from whole apples, it is a good practice to remove the seeds before blending to prevent any potential release of amygdalin. To avoid patulin, always inspect apples for mold or rot before eating or processing them. If an apple is bruised or showing signs of decay, it should be discarded to prevent potential contamination.

Conclusion

The question of which toxin is found in apples? has a two-part answer. While the fruit itself is a nutritious and healthy food, two different toxins can be associated with apples in specific situations. Amygdalin, a compound capable of producing cyanide, is locked safely inside the hard shell of the seeds and poses a negligible risk unless a large quantity of crushed seeds is consumed. Patulin, a mycotoxin, can develop on rotten or moldy apples and is a risk factor for improperly processed apple products. For safe consumption, simply avoid eating the core and seeds, and always inspect fresh apples for signs of decay. Accidental ingestion of a few whole seeds is not a cause for concern. For further reading on food contaminants, refer to sources like the National Institutes of Health (NIH).

Frequently Asked Questions

Apple seeds contain amygdalin, a cyanogenic compound that can release toxic hydrogen cyanide if the seeds are crushed or chewed. While technically poisonous in large quantities, swallowing a few whole seeds is unlikely to cause harm.

If you accidentally swallow one or two whole apple seeds, you should not be concerned. The seeds have a hard outer shell that resists digestion, and they will likely pass through your body harmlessly.

A healthy adult would need to chew and consume a large quantity of crushed apple seeds, possibly hundreds, to experience symptoms of cyanide poisoning. This is not a realistic risk with normal fruit consumption.

Symptoms of cyanide poisoning can include headache, dizziness, nausea, and confusion. In severe cases, it can lead to seizures and loss of consciousness, but this would only occur from a massive dose of crushed seeds.

Commercially available and pasteurized apple juice is considered safe. A 2018 study found that cyanide was not detectable in pasteurized apple juice. However, some raw, home-blended juices that include whole, crushed apples may contain detectable amounts of amygdalin or cyanide.

Amygdalin is a compound found in apple seeds, while cyanide is the highly toxic substance that can be released from amygdalin when the seeds are chewed and digested. Amygdalin itself is not cyanide.

No, the flesh of a healthy apple is not toxic and is packed with vitamins and fiber. The toxic compound, amygdalin, is confined to the seeds.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.