Skip to content

Who Should Avoid Star Anise and Why

4 min read

In 2003, the U.S. FDA issued a consumer warning about star anise tea after reports of serious side effects, primarily due to contamination. The seemingly harmless spice carries significant risks for several groups of people who should avoid star anise entirely to prevent adverse health reactions.

Quick Summary

Certain individuals must avoid star anise due to significant health risks, including contamination with a toxic look-alike, harmful effects on infants, potential complications during pregnancy and breastfeeding, and negative interactions with medications or estrogen-sensitive conditions.

Key Points

  • Infants and Children: Avoid giving star anise to infants and children due to a high risk of poisoning from contamination and reported severe neurological and gastrointestinal effects.

  • Pregnant and Breastfeeding Individuals: Star anise is potentially unsafe for pregnant and nursing women, as safety has not been established and toxic compounds could pass to the baby.

  • Risk of Contamination: The biggest danger is the indistinguishable toxic Japanese star anise, which can be mistakenly mixed with safe Chinese star anise, causing severe neurotoxicity.

  • Drug Interactions: Star anise can interact dangerously with medications like blood thinners, hormone treatments, and diabetes drugs.

  • Hormone-Sensitive Conditions: Individuals with estrogen-sensitive conditions, such as certain cancers, should avoid star anise due to its estrogen-mimicking properties.

  • Allergies: People with known allergies to star anise or related spices should avoid consumption to prevent severe allergic reactions.

In This Article

The Critical Risk of Contamination with Japanese Star Anise

One of the most significant and immediate dangers associated with star anise consumption is the potential for contamination with its highly toxic look-alike, Japanese star anise (Illicium anisatum). These two species are nearly impossible to distinguish by appearance alone, creating a severe risk for consumers. While the Chinese star anise (Illicium verum) is commonly used in cooking and is generally safe in small culinary amounts, the Japanese variety contains potent neurotoxins like anisatin, which can cause severe health problems.

Symptoms of Japanese Star Anise Poisoning

Accidental ingestion of the toxic Japanese star anise can lead to severe gastrointestinal and neurological symptoms within hours. Symptoms can include nausea, vomiting, abdominal cramps, and diarrhea, progressing to more serious issues like tremors, seizures, and hallucinations. In infants, even small amounts have caused severe neurological and gastrointestinal damage.

Star Anise is Unsafe for Infants and Children

Parents and caregivers should never give star anise, particularly in the form of tea, to infants and young children. Numerous case reports have documented severe neurological and gastrointestinal adverse effects in infants who consumed star anise tea, including seizures, vomiting, and extreme irritability. While many of these cases are believed to be caused by contamination, the risk is too high to warrant any use. Since it's nearly impossible for a consumer to verify the purity of a product, any star anise tea should be avoided for pediatric use.

Pregnant and Breastfeeding Individuals Should Exercise Extreme Caution

The safety of star anise during pregnancy and breastfeeding has not been reliably established through sufficient research. Due to the potential for contamination and the lack of robust safety data, health authorities recommend that pregnant and breastfeeding women avoid star anise, especially in medicinal amounts or teas. Some of its active compounds, including anethole, can pass into breast milk, potentially causing harm to an infant.

Individuals with Hormone-Sensitive Conditions

Star anise contains compounds that can mimic the effects of estrogen in the body. Therefore, individuals with hormone-sensitive conditions should avoid this spice. This includes people diagnosed with conditions such as:

  • Breast cancer
  • Uterine cancer
  • Ovarian cancer
  • Endometriosis

Use of star anise in these cases could potentially exacerbate or interfere with treatment for the condition. It is crucial to consult a healthcare provider before using star anise if you have a history of these or related health issues.

People with Allergies to Star Anise

While relatively rare, allergic reactions to star anise are possible, particularly in individuals with sensitivities to other plants in the Apiaceae family, such as fennel or celery. Symptoms can range from mild skin rashes, itching, and swelling to more severe reactions like anaphylaxis in extreme cases. Anyone with a known allergy or a history of allergic reactions to spices should avoid star anise.

Star Anise Can Interact with Certain Medications

Star anise can affect how the body processes some medications due to its bioactive compounds. Individuals taking certain drugs should be cautious or avoid star anise entirely:

  • Blood Thinners: Star anise contains shikimic acid, which has potential blood-thinning activity. This can increase the risk of bleeding and bruising in people on anticoagulant medications like warfarin.
  • Estrogen-Based Medications: As star anise can mimic estrogen, it may interfere with birth control pills, hormonal replacement therapy, and anti-estrogen medications like Tamoxifen.
  • Diabetes Medications: Some studies suggest star anise may lower blood sugar, potentially causing blood sugar levels to drop too low in individuals taking antidiabetes drugs.
  • Sedatives: The sedative properties of star anise can be intensified when taken alongside other sedative medications, increasing side effects.

Comparison Table: Who Should Avoid Star Anise?

Group Reason for Avoidance Potential Health Risk
Infants and Children High risk of toxicity from contamination and unknown effects Seizures, vomiting, neurotoxicity, and gastrointestinal distress.
Pregnant and Breastfeeding Individuals Safety is not established; potential for contamination Harm to the fetus or infant; compounds may pass into breast milk.
Individuals with Allergies Allergic reaction to the spice or related compounds Mild to severe symptoms, including anaphylaxis.
People with Hormone-Sensitive Conditions Estrogen-mimicking compounds could affect the condition Exacerbation of breast, uterine, or ovarian cancer; interference with treatment.
Individuals Taking Specific Medications Potential for drug interactions Increased risk of bleeding, altered medication effectiveness, or exaggerated side effects.
Anyone Consuming Star Anise Tea Risk of toxic Japanese star anise contamination Severe neurotoxic and gastrointestinal symptoms.

The Safest Approach: Minimal Culinary Use

For most healthy adults, star anise is safe when used in minimal quantities for flavoring food, as its potency is significantly diluted. However, relying on larger doses for medicinal purposes, such as in teas or supplements, dramatically increases the risk of contamination and adverse effects. The safest course of action for anyone not in a high-risk group is to use star anise sparingly in cooking and to purchase it from highly reputable suppliers. If you have any health conditions or are on medication, a healthcare provider should always be consulted before consuming star anise.

Conclusion

While star anise is a flavorful and aromatic spice used in many cuisines, it is not safe for everyone. Infants, pregnant and breastfeeding women, those with hormone-sensitive conditions, individuals with allergies, and those on specific medications should all avoid star anise due to the serious risks involved. The constant threat of contamination with poisonous Japanese star anise further complicates its use, making caution and avoidance the wisest choice for vulnerable populations. For those without contraindications, responsible, and minimal culinary use remains the best practice. When in doubt, it is always best to err on the side of caution and consult a healthcare professional. For more information on general herbal safety, the National Center for Complementary and Integrative Health provides resources on common herbs and botanicals [https://www.nccih.nih.gov/health/herbsataglance].

Frequently Asked Questions

Star anise tea is potentially dangerous primarily because of the risk of contamination with toxic Japanese star anise, which looks identical but contains potent neurotoxins. Case reports have linked star anise tea, especially when given to infants, with severe health issues like seizures and vomiting.

No, you should never give star anise to an infant for colic or any other purpose. There have been numerous reports of infants experiencing severe neurological symptoms and gastrointestinal distress after consuming star anise tea, mainly due to contamination risks.

The main difference is toxicity. Chinese star anise (Illicium verum) is the culinary spice, while Japanese star anise (Illicium anisatum) is poisonous and contains potent neurotoxins. They are visually almost identical, making contamination a serious risk.

Yes, large amounts of star anise might interfere with birth control pills and other estrogen-based medications. It contains compounds that can mimic estrogen, potentially altering the medication's effectiveness.

No, it is not considered safe to consume star anise in medicinal amounts during pregnancy or breastfeeding. Due to the risk of contamination and lack of reliable safety information, pregnant and lactating women should avoid it.

Yes, some individuals may have an allergic reaction to star anise, especially if they are allergic to related spices like fennel or celery. Reactions can include skin rashes, itching, swelling, or more severe responses like anaphylaxis.

Individuals with hormone-sensitive conditions, such as breast, uterine, or ovarian cancer, should avoid star anise. Its estrogen-like effects could potentially worsen the condition or interfere with treatments.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.