Understanding DGL vs. Regular Licorice
To understand who should not take DGL licorice, it's crucial to first differentiate it from standard licorice root. Regular licorice contains glycyrrhizin, a compound known to cause side effects such as elevated blood pressure, electrolyte imbalances (low potassium), and fluid retention, especially with long-term use or high doses. DGL, or deglycyrrhizinated licorice, is a form of licorice where this problematic compound has been largely removed. This makes DGL a safer alternative for some, but not for everyone.
Conditions That Warrant Avoiding DGL
Even with the glycyrrhizin removed, certain health conditions still make DGL a risky supplement choice. Consulting a healthcare provider is essential before starting any new supplement regimen.
- Pregnancy and Breastfeeding: The National Center for Complementary and Integrative Health (NCCIH) advises against using licorice root during pregnancy, citing risks like premature delivery. While DGL removes the primary culprit (glycyrrhizin), some sources suggest avoiding licorice products altogether as a precautionary measure due to limited safety data during pregnancy and breastfeeding.
- Hormone-Sensitive Conditions: Licorice has been known to exert estrogen-like effects in the body. For this reason, individuals with hormone-sensitive conditions such as breast, ovarian, or uterine cancer, as well as endometriosis or uterine fibroids, should avoid DGL.
- Kidney or Liver Disease: Although DGL minimizes the risks associated with glycyrrhizin, individuals with severe kidney or liver disease should still be cautious. These conditions can affect how the body processes supplements, and any potential residual compounds or interactions could pose a risk.
Potential Drug Interactions
Despite being safer than regular licorice, DGL can still interact with certain medications. This is a critical consideration for anyone managing a chronic condition with pharmaceuticals.
- Medications that Deplete Potassium: Though DGL is not known to significantly lower potassium like regular licorice, caution is advised when taking diuretics or corticosteroids, which also deplete potassium. Combining these could potentially amplify the effect.
- Blood Thinners (Anticoagulants): Licorice can interfere with the effectiveness of blood-thinning medications like warfarin, potentially increasing the risk of blood clots.
- Heart Medications: Interactions with heart medications such as digoxin have been reported, primarily due to potential effects on potassium levels.
DGL vs. Regular Licorice Root for Safety
| Feature | DGL (Deglycyrrhizinated Licorice) | Regular Licorice Root (with Glycyrrhizin) |
|---|---|---|
| Key Compound | Glycyrrhizin mostly removed | Glycyrrhizin present |
| High Blood Pressure Risk | Greatly reduced; generally considered safe | High risk of raising blood pressure |
| Potassium Depletion | Minimized risk | Significant risk |
| Use in Pregnancy | Generally advised to avoid due to lack of data | Strongly contraindicated |
| Heart Conditions | Use with caution; consult a doctor | Should be avoided |
| Drug Interactions | Potential interactions still exist; consult a doctor | Numerous and serious interactions |
Potential Residual Risks for Specific Groups
While the main health concern, glycyrrhizin, is removed, no supplement is entirely without risk for all individuals. For instance, while less common, some sensitive people may experience a slight rise in blood pressure from DGL. Allergic reactions are also possible with any herbal product. Ultimately, a cautious approach is best for individuals with compromised health, and an informed discussion with a healthcare provider is paramount.
What to Do Before Taking DGL
For most healthy adults, DGL is considered safe when taken as directed for up to four months. However, before incorporating it into your routine, take these steps:
- Consult a Professional: Always speak with a doctor or pharmacist, especially if you have pre-existing health conditions or take other medications.
- Check the Label: Ensure your supplement clearly states it is 'deglycyrrhizinated' to avoid products containing glycyrrhizin.
- Monitor Your Body: Be aware of any unusual symptoms and discontinue use if adverse effects occur.
Conclusion: A Cautious Approach to DGL Licorice
While DGL offers a safer alternative to regular licorice for digestive issues, it is not risk-free for everyone. Individuals who are pregnant or breastfeeding, those with hormone-sensitive cancers, and those with serious kidney or liver conditions should avoid it. Furthermore, anyone on prescription medications, especially for heart problems, blood thinning, or conditions requiring potassium-depleting drugs, must consult their doctor to prevent potential interactions. The removal of glycyrrhizin significantly reduces risk, but it does not eliminate the need for personal medical evaluation and caution when using DGL licorice.
Sources
For additional information on the safety and use of licorice supplements, consider visiting reliable resources such as the National Center for Complementary and Integrative Health. Licorice Root: Usefulness and Safety
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Consult with a healthcare professional before starting any new supplement.
