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Who Should Not Take Elderberries? A Comprehensive Safety Guide

4 min read

While often praised for its immune-boosting properties, elderberry supplements are not safe for everyone. Certain individuals, such as those with autoimmune diseases, pregnant or breastfeeding women, and young children, should avoid taking elderberries due to potential health risks and a lack of safety research.

Quick Summary

This guide details the specific groups who should avoid elderberry supplements, including individuals with autoimmune conditions, pregnant or nursing women, young children, and those on certain medications. It also covers the risks associated with consuming uncooked elderberries and highlights the importance of consulting a healthcare provider before use.

Key Points

  • Autoimmune Patients: Individuals with autoimmune diseases like lupus or rheumatoid arthritis should avoid elderberry, as its immune-stimulating effects could exacerbate symptoms.

  • Pregnant or Breastfeeding Women: Due to a lack of safety research, elderberry is not recommended for women who are pregnant or nursing.

  • Young Children: Elderberry supplements are not recommended for young children, especially under five, and should be used with caution in older kids after consulting a pediatrician.

  • Immunosuppressant Medications: Elderberry can interfere with immunosuppressant drugs, making them less effective for transplant recipients and others.

  • Raw Elderberries are Toxic: Never consume raw, unripe elderberries, or the leaves, stems, and bark of the elder plant, as they contain cyanide-producing compounds.

  • Drug Interactions: Elderberry can interact with other medications, including diuretics and some diabetes drugs.

  • Allergic Reactions: Though rare, elderberry can cause allergic reactions in some individuals, presenting as hives or difficulty breathing.

In This Article

Essential Safety Precautions When Considering Elderberry

Elderberry, derived from the berries of the Sambucus nigra plant, has been a traditional remedy for centuries, prized for its potential to relieve cold and flu symptoms. However, the use of elderberry supplements requires caution, as not everyone can take them safely. A significant concern is the presence of a cyanide-producing compound, particularly in the raw, unripe berries, seeds, stems, and leaves, which can be toxic if not properly processed through cooking. Beyond this, specific health conditions and life stages can create additional risks, warranting avoidance of the supplement entirely. It is crucial to understand these contraindications to protect your health and the health of your family.

Autoimmune Disorders and the Immune System

One of the most critical groups who should not take elderberries are individuals with autoimmune diseases. Conditions like multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), and rheumatoid arthritis (RA) are characterized by an overactive immune system that mistakenly attacks healthy body tissues. Since elderberry is known for its ability to stimulate or boost the immune system, taking it could potentially worsen the symptoms of an autoimmune disorder. This potential for immune system overstimulation poses a direct conflict with the underlying pathology of these diseases. For those managing an autoimmune disease, it is best to avoid elderberry supplements and consult a healthcare provider for safe immune support strategies. This is particularly important for patients on immunosuppressant medications, as elderberry could interfere with their effectiveness.

Pregnancy, Breastfeeding, and Young Children

Another group that should exercise extreme caution or completely avoid elderberry is pregnant or breastfeeding women. The primary reason for this is a lack of sufficient research to determine its safety during these critical periods. The U.S. Food and Drug Administration (FDA) does not regulate herbal supplements with the same rigor as prescription drugs, and no conclusive data exists on how elderberry consumption affects pregnancy or breastfeeding. Healthcare providers typically recommend that expectant and nursing mothers err on the side of caution and avoid supplements without clear evidence of safety. Similarly, due to insufficient data, elderberry supplements are not generally recommended for children under 5, and some experts suggest caution for those under 12. Some elderberry syrups for infants also contain honey, which is unsafe for babies under 12 months due to the risk of botulism. For children, sticking to proven, regulated remedies or consulting a pediatrician is the safest course of action.

Raw Elderberries and Toxicity

Regardless of health status, no one should consume raw or improperly prepared elderberries. The uncooked fruit, as well as the leaves, stems, and bark of the elder plant, contain cyanogenic glycosides that can release cyanide into the body when ingested. Symptoms of this poisoning include nausea, vomiting, diarrhea, and in large doses, more severe effects. Cooking elderberries thoroughly, as is done for jams or reputable commercial supplements, eliminates this toxin. Consumers should only purchase elderberry products from reliable, third-party tested manufacturers to ensure proper preparation.

Medications and Other Health Considerations

Elderberry's effects can also clash with certain medications. As a natural diuretic, it may increase urination. This can be problematic for individuals already taking prescription diuretics, potentially leading to dehydration. Furthermore, elderberry may interfere with diabetes medications and laxatives. Anyone with gastrointestinal issues, such as irritable bowel syndrome (IBS), should also be mindful, as elderberry products can upset the GI tract, causing nausea, vomiting, or diarrhea in some individuals. Patients undergoing chemotherapy should consult their doctor before use, as elderberry's properties could have adverse effects.

Comparing Elderberry Use in Different Populations

Population Group Safety Profile of Elderberry Supplement Key Considerations & Risks
Adults (healthy) Generally considered safe when taken properly and for short durations (up to 12 weeks). Watch for potential GI upset (nausea, diarrhea); ensure the product is from a reputable source.
Pregnant/Breastfeeding Women Not recommended due to insufficient safety data and potential for immune stimulation. Risk to the fetus or infant is unknown; safest to avoid completely.
Young Children (under 5) Not recommended; safety data is lacking. Risk of botulism from honey in some syrups for infants under 1. Immune system is still developing; potential risks are not fully understood.
Autoimmune Patients Not recommended, especially for those on immunosuppressants. May overstimulate the immune system and worsen disease symptoms.
Individuals on Immunosuppressants Avoid; elderberry can decrease the effectiveness of these vital medications. Counteracts the intended effect of immunosuppressive therapy, risking organ rejection or disease flare-ups.
Diabetic Patients Use with caution and medical supervision; potential for interaction with diabetes medications. May alter blood sugar levels; requires careful monitoring.
Individuals with Gastrointestinal Issues May cause GI upset (nausea, vomiting, diarrhea). Should avoid if prone to GI distress or if symptoms worsen.

The Importance of Medical Consultation

Given the wide array of potential contraindications and drug interactions, consulting a healthcare provider before beginning any elderberry regimen is a critical step. Unlike pharmaceutical drugs, herbal supplements like elderberry lack strict government oversight, meaning product consistency and safety can vary significantly between brands. A doctor can help weigh the potential benefits against your personal health history, current medications, and specific needs to make an informed decision. This is particularly vital for those with pre-existing conditions, women who are pregnant or nursing, and for use in children.

Conclusion

While elderberry offers potential benefits for immune support, its use is not universally safe. Individuals with autoimmune diseases, those who are pregnant or breastfeeding, and young children should generally avoid elderberry supplements due to insufficient safety data or the potential for adverse immune reactions. Furthermore, interactions with various medications and the toxicity of raw elderberries underscore the importance of proper preparation and medical consultation. Prioritizing safety by understanding these contraindications is essential for anyone considering adding elderberry to their health routine. For more information on complementary and integrative health, consult the National Center for Complementary and Integrative Health (NCCIH) at https://www.nccih.nih.gov/health/elderberry.

Frequently Asked Questions

No, people with autoimmune diseases like multiple sclerosis, lupus, or rheumatoid arthritis should not take elderberry. Elderberry can stimulate the immune system, which may worsen the symptoms of these conditions where the immune system is already overactive.

Elderberry is not recommended for pregnant or breastfeeding women. There is insufficient research to confirm its safety for use during pregnancy or while nursing, so healthcare providers advise avoiding it to be cautious.

Raw elderberries and other parts of the elder plant, like the stems, leaves, and unripe berries, contain cyanogenic glycosides. When ingested, these compounds can release cyanide into the body, causing symptoms like nausea, vomiting, and diarrhea.

Individuals taking immunosuppressant drugs, such as organ transplant recipients, should not take elderberry. Elderberry boosts immune activity, which can counteract the effects of these medications and risk organ rejection.

Children under five should not take elderberry supplements due to a lack of safety data. Always consult a pediatrician before giving elderberry or any herbal supplement to a child, as regulation varies and some products may contain unsafe ingredients.

When taken in supplement form, side effects may include gastrointestinal upset such as nausea, vomiting, and diarrhea. This can be particularly true for individuals with sensitive stomachs or pre-existing GI issues.

Yes, elderberry can interact with several medications. It has diuretic properties and can interact with diuretic drugs. It may also interfere with certain diabetes medications and can potentially reduce the effectiveness of immunosuppressants.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.