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Is AlgaeCal Safe to Use? A Comprehensive Safety Review

4 min read

According to a 2016 study published in the Journal of the American College of Nutrition, AlgaeCal was not associated with adverse health effects and showed potential for increasing bone density. However, like any supplement, it is crucial to understand if AlgaeCal is safe to use for your specific health situation, including its ingredients and possible interactions.

Quick Summary

This review examines AlgaeCal's safety profile, exploring its plant-based source, potential side effects, medication interactions, and suitability for various health conditions. It compares AlgaeCal with traditional supplements and provides details on its clinical backing and ingredients.

Key Points

  • Generally Safe: Clinical and toxicological studies confirm AlgaeCal has a broad safety profile and is well-tolerated by most people.

  • Potential for Mild Side Effects: While rare and less frequent than with rock-based calcium, mild digestive issues like gas or upset stomach have been reported.

  • Precaution with Anticoagulants: Individuals on older blood thinners like warfarin must avoid AlgaeCal Plus due to its Vitamin K2 content and should consult their doctor.

  • Special Warnings for Strontium Boost: The companion supplement is contraindicated for pregnant/nursing women and those with chronic kidney disease.

  • Superior to Rock-Based Calcium: Its plant-based source and whole-food matrix lead to better absorption and fewer adverse digestive effects than traditional calcium supplements.

  • Medication Interactions: Separation is required when taking AlgaeCal with certain medications like thyroid drugs, specific antibiotics, and iron supplements.

In This Article

Understanding the Safety of AlgaeCal

AlgaeCal is a plant-based calcium supplement, derived from the marine algae Mesophyllum superpositum. Unlike many traditional calcium supplements sourced from rocks, its natural origin is often highlighted as a key benefit, especially concerning digestion. The company emphasizes its whole-food nature, claiming superior absorption and fewer side effects like constipation and bloating, which are often associated with rock-based calcium carbonate. Extensive testing and clinical studies are used to support these safety claims.

Clinical Evidence and GRAS Status

  • Toxicological Evaluation: Before receiving Generally Recognized as Safe (GRAS) status from the FDA in 2010, AlgaeCal underwent several toxicological studies. These studies established a broad-spectrum safety profile and found no significant toxicity, including during pregnancy in rat models.
  • Long-Term Human Trials: A significant 7-year longitudinal study, published in the Journal of the American College of Nutrition, examined the safety and efficacy of AlgaeCal (with Strontium Boost). The study followed consumers for up to 7 years, analyzing blood chemistry panels and bone mineral density (BMD). Results showed sustained BMD increases with no reported adverse effects or safety concerns.
  • Cardiovascular Safety: Concerns about cardiovascular risk have been raised for some calcium supplements. AlgaeCal Plus includes vitamin K2 (MK-7), which is believed to help direct calcium into bones and away from soft tissues like arteries. Clinical studies on AlgaeCal have not shown adverse effects on cardiovascular markers.

AlgaeCal vs. Traditional Calcium Supplements

Feature AlgaeCal (Plant-Based) Traditional (Rock-Based)
Source Marine algae (Mesophyllum superpositum) Limestone or marble (calcium carbonate)
Mineral Profile Contains calcium plus 13 essential trace minerals Often contains calcium with few or no trace minerals
Absorption Pre-digested by algae, more easily absorbed by the body Can be difficult for the body to absorb effectively
Digestive Impact Less likely to cause bloating, gas, or constipation Common side effects include constipation, bloating, and gas
Bone Density Impact Clinically shown to increase bone density Generally only slows annual bone loss

Potential Side Effects and Precautions

While largely considered safe, side effects can still occur, and precautions are necessary for certain individuals and medication regimens.

Common and Less Common Side Effects

Most users report no significant side effects, but some may experience mild gastrointestinal discomfort, upset stomach, diarrhea, or headaches. These effects are generally less severe and less frequent than with traditional calcium supplements. The presence of magnesium in AlgaeCal is intended to help balance calcium and reduce digestive issues.

Medication and Health Interactions

  • Anticoagulants: The AlgaeCal Plus product contains Vitamin K2 (MK-7), which can interfere with older anticoagulant medications like warfarin (Coumadin). Patients on these medications should consult a doctor and may need to use the basic AlgaeCal product, which does not contain vitamin K2.
  • Strontium Boost: The companion supplement Strontium Boost is not recommended for pregnant or nursing mothers or for individuals with chronic kidney disease, as the kidneys eliminate strontium. Strontium should also be taken at least two hours away from calcium.
  • Other Medications: Some medications, such as thyroid medication, certain antibiotics, and iron supplements, need to be taken at least a few hours apart from AlgaeCal to ensure proper absorption and efficacy.
  • Pregnant or Nursing Women: Always consult a healthcare provider before taking AlgaeCal or any new supplement during pregnancy or breastfeeding.

What to Consider Before Use

  1. Consult Your Doctor: Before starting AlgaeCal, especially if you have pre-existing health conditions like kidney disease or are taking other medications, consult a healthcare provider.
  2. Choose the Right Product: If you are on an anticoagulant, verify with your doctor whether AlgaeCal or AlgaeCal Plus is the appropriate choice, or if a different course of action is needed.
  3. Understand Your Goals: While AlgaeCal is clinically shown to increase bone density, it is important to remember it is a supplement. It should be used as part of a comprehensive bone health plan that includes diet and exercise.
  4. Adhere to Dosage: Follow recommended dosing instructions, including splitting doses for optimal absorption and taking with food.

Whole Food vs. Synthetic Comparison

  • Whole-Food Matrix: AlgaeCal is sourced as a whole-food substance, meaning the calcium and other minerals are in a form the body naturally recognizes and is better able to use.
  • Superior Digestion: The plant-based nature of AlgaeCal leads to fewer digestive issues compared to the hard-to-digest rock-based calcium found in many cheaper supplements.

Conclusion

Based on available research and toxicological evaluations, AlgaeCal appears to be a safe option for most adults seeking to support their bone health. Its plant-based origin offers potential advantages in absorption and digestive comfort over traditional rock-sourced calcium supplements. Key safety considerations include potential interactions with specific anticoagulant medications (due to Vitamin K2 in AlgaeCal Plus) and avoiding the companion Strontium Boost product in cases of pregnancy, breastfeeding, or chronic kidney disease. It is always recommended to consult a healthcare professional before beginning any new supplement regimen to ensure it is appropriate for your individual health status. For more information on dietary calcium and supplementation, visit the National Institutes of Health website.

Frequently Asked Questions

Most users report no side effects, and studies show a good safety profile. However, some have experienced mild gastrointestinal issues, upset stomach, or headaches.

It depends on the medication. AlgaeCal Plus contains Vitamin K2, which can interfere with older anticoagulants like warfarin. The basic AlgaeCal product is an alternative for those who cannot switch to newer blood thinners.

Individuals with chronic kidney disease should avoid AlgaeCal's Strontium Boost companion product. Always consult your healthcare provider before taking any supplement if you have a medical condition.

The strontium citrate in Strontium Boost is considered safe and has a different profile than the synthetic strontium ranelate, which was associated with safety issues. However, it should not be taken by those with kidney disease, pregnant, or nursing.

Because it comes from a whole-food source, AlgaeCal is more easily digested and absorbed by the body compared to rock-based calcium, leading to fewer reported digestive side effects like bloating and constipation.

Yes, pregnant and nursing women should consult a healthcare professional before taking AlgaeCal or its related products. Strontium Boost is not recommended for this group.

Yes. AlgaeCal should be separated by a few hours from certain medications, including thyroid medication, specific antibiotics, and iron supplements, to avoid interaction and ensure proper absorption.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.