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Is Sweetener 951 Natural or Artificial? Understanding Aspartame's Origin

4 min read

Aspartame, identified as sweetener 951 in Europe and other regions, is approximately 200 times sweeter than regular table sugar. Given that it's made from amino acids—the same building blocks of protein—consumers often ask: is sweetener 951 natural or artificial?

Quick Summary

Sweetener 951, more commonly known as aspartame, is an artificial, synthetically produced sweetener. Its creation involves a chemical synthesis process, despite being derived from naturally occurring amino acids.

Key Points

  • Artificial Designation: Sweetener 951 (aspartame) is an artificial, not natural, sweetener because it is produced through chemical synthesis.

  • Amino Acid Origin: Aspartame is synthesized from two naturally occurring amino acids, aspartic acid and phenylalanine, but this does not make the final product natural.

  • Intense Sweetness: This chemical sweetener is approximately 200 times sweeter than table sugar, so only a small amount is needed to achieve the desired sweetness.

  • Not Heat-Stable: Aspartame loses its sweetness when exposed to high temperatures and is therefore not typically used in baked goods.

  • Regulatory Approval: Major health authorities like the FDA and EFSA have found aspartame to be safe for human consumption within established acceptable daily intake levels.

  • Potential Hazard Classification: In 2023, the WHO's cancer research agency classified aspartame as "possibly carcinogenic to humans" based on limited evidence, but a separate WHO expert panel maintained its safety rating based on consumption levels.

In This Article

Sweetener 951 is the European food additive code for aspartame, one of the most widely used artificial sweeteners in the world. While the components used to create aspartame—the amino acids aspartic acid and phenylalanine—do exist naturally, the final product is not natural. The process used to combine these components is a man-made chemical synthesis, which is why aspartame is classified as an artificial sweetener.

The Difference Between Natural and Artificial Sweeteners

Understanding the distinction between natural and artificial ingredients is key to grasping aspartame's classification. Natural sweeteners, such as honey, maple syrup, or stevia, are derived directly from natural sources and undergo minimal processing. They contain calories and often have a more complex nutritional profile. In contrast, artificial sweeteners are created in a laboratory through chemical synthesis. They are often many times sweeter than sugar and contain little to no calories. Aspartame falls squarely into this second category due to its manufacturing process.

The Chemical Production of Sweetener 951

Aspartame was discovered by accident in 1965 by chemist James Schlatter during synthesis experiments. Its production process, now primarily done through advanced biotechnology and fermentation, involves several chemical steps to create the final compound.

  1. Fermentation: The amino acids L-aspartic acid and L-phenylalanine are produced through fermentation using specific bacteria.
  2. Isolation: The amino acids are isolated and purified from the bacterial culture.
  3. Synthesis: Chemical reactions are used to modify the amino acids and link them together. The phenylalanine component is combined with methanol to form a methyl ester.
  4. Purification: The resulting product undergoes further chemical reactions and purification steps, like crystallization and filtration, to produce the final, intensely sweet aspartame crystals.

The Building Blocks: Amino Acids

It is true that aspartame is made from amino acids, the basic units of protein that are found in many common foods like meat, dairy, and vegetables. Upon digestion, aspartame breaks down into these same amino acids, plus a small amount of methanol, which the body then processes. However, the crucial difference lies in the synthesis process itself—taking individual amino acids and chemically combining them in a specific way to create a novel compound that doesn't exist in nature. This is what differentiates it from a naturally derived sweetener.

Aspartame vs. Other Sweeteners: A Comparison

To better understand aspartame's place in the world of sweeteners, here is a comparison with a natural alternative (stevia) and traditional sugar.

Feature Aspartame (Sweetener 951) Steviol Glycosides (from Stevia) Sucrose (Table Sugar)
Origin Synthetically produced via chemical synthesis Extracted and purified from the stevia plant leaf Extracted from natural plant sources like sugarcane or sugar beets
Sweetness Level ~200 times sweeter than sucrose 200-400 times sweeter than sucrose Standard reference (1x)
Calorie Count ~4 calories per gram, but used in such small amounts it is considered low- or no-calorie Zero calories ~4 calories per gram
How it's Made Chemical synthesis of amino acids Purification of extracts from the stevia plant Crystallization from plant juices
Key Characteristic Low-calorie, widely available artificial sweetener Zero-calorie, plant-based sweetener Standard, high-calorie sugar

Common Foods Containing Sweetener 951

Because of its intense sweetness and low-calorie nature, aspartame is used in a vast array of food and beverage products around the world. It is important to note that it is not heat-stable and loses its sweetness when heated, which is why it is typically not used in baked goods. Common products containing sweetener 951 include:

  • Diet soft drinks and powdered beverage mixes
  • Sugar-free chewing gum
  • Diet yogurts and other dairy products
  • Tabletop sweeteners sold under brand names like NutraSweet and Equal
  • Certain cereals, puddings, gelatins, and confections

The Safety and Regulation of Aspartame

Over the years, the safety of aspartame has been extensively reviewed by numerous health authorities globally. Agencies like the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) have consistently concluded that aspartame is safe for consumption within an acceptable daily intake (ADI) for the general population.

However, in July 2023, the International Agency for Research on Cancer (IARC), a part of the World Health Organization (WHO), classified aspartame as "possibly carcinogenic to humans" (Group 2B). This classification is based on "limited evidence" from animal and human studies and does not take into account typical consumption levels, but rather identifies a potential hazard. In response, the separate WHO expert committee on food additives (JECFA) reaffirmed its long-standing ADI, concluding there was no sufficient reason to change the safe intake levels. For most people, consuming below the ADI means staying well within safe limits, though concerns persist among some consumers.

One specific exception is for individuals with phenylketonuria (PKU), a rare genetic disorder. People with PKU cannot metabolize the phenylalanine in aspartame, and so products containing it must carry a warning label.

Conclusion: An Artificial Sweetener with Natural Roots

In summary, sweetener 951, or aspartame, is unequivocally an artificial sweetener. While it is created from amino acids, which are naturally occurring building blocks, the finished product is the result of a synthetic chemical process. This manufacturing distinction is what places it in the artificial category, separating it from natural sweeteners like stevia or honey. Its widespread use in low-calorie products makes it a staple for those looking to reduce sugar intake, though it is important to be aware of how different health organizations view its safety. For those interested in deeper scientific context, exploring the extensive studies and regulatory history can provide additional insight, as referenced on sites like the Wikipedia page for Aspartame.

Frequently Asked Questions

Sweetener 951 is the European food additive code for aspartame, a widely used artificial, low-calorie sweetener and sugar substitute.

Aspartame is made through a synthetic chemical process that combines two naturally occurring amino acids: aspartic acid and phenylalanine. The process does not occur naturally.

Yes, aspartame technically contains about 4 calories per gram, similar to sugar. However, because it is so much sweeter, only a tiny amount is needed to sweeten food, making the calorie contribution negligible.

Aspartame has been deemed safe by major regulatory bodies like the FDA and EFSA within an acceptable daily intake. In 2023, a WHO agency classified it as "possibly carcinogenic" based on limited evidence, but a separate WHO panel maintained its safety rating.

Aspartame is found in many sugar-free and diet products, including diet sodas, sugar-free chewing gum, diet yogurts, instant beverages, and tabletop sweeteners like Equal and NutraSweet.

Yes. People with the rare genetic disorder PKU cannot properly metabolize phenylalanine, one of aspartame's components. Products containing aspartame must carry a warning label for these individuals.

Yes. The body processes artificial sweeteners like aspartame differently than natural ones like sugar or honey. While sugar raises blood glucose, aspartame does not, which is why it is often recommended for people with diabetes.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.