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Is sweetener 955 natural or artificial? The truth about Sucralose

5 min read

Despite being derived from table sugar (sucrose), sweetener 955, known as sucralose, is a completely artificial compound created through a multi-step chemical process. It is approximately 600 times sweeter than sugar and contains zero calories, making it a popular low-calorie alternative.

Quick Summary

Sweetener 955, or sucralose, is a synthetic sweetener chemically altered from sucrose. It is calorie-free, heat-stable, and used widely in foods and beverages.

Key Points

  • Sucralose is artificial: Sweetener 955, known as sucralose, is a man-made chemical compound, not a natural product, despite being derived from sugar.

  • Chlorinated compound: The manufacturing process involves replacing three hydroxyl groups on a sucrose molecule with chlorine atoms, fundamentally changing its structure.

  • Zero calories: Due to its modified structure, the body does not metabolize sucralose, which is why it has no calories.

  • Debated long-term effects: While deemed safe by major health organizations, sucralose's long-term effects on the gut microbiome and metabolism are still debated among researchers.

  • Stable for cooking: Sucralose is heat-stable and can be used in baking, but some studies raise concerns about potential compound formation at very high temperatures.

  • Natural alternatives exist: For those avoiding artificial sweeteners, options like stevia and monk fruit, which are derived from plants, are available.

In This Article

What is sweetener 955?

Sweetener 955 is the food additive code for sucralose, a non-nutritive (zero-calorie) artificial sweetener. First discovered in 1976, it was approved for use in the United States by the FDA in 1998 and is now found in thousands of food and beverage products worldwide. It is most widely known by the brand name Splenda, and can be found in diet sodas, sugar-free gum, low-calorie baked goods, and tabletop sweeteners. Sucralose is popular with consumers and manufacturers alike because it offers intense sweetness without the calories of sugar and is stable under a wide range of conditions, including high heat, making it suitable for cooking and baking. However, the key distinction lies in its origin; while it is derived from a natural substance, the final product is not found in nature.

The manufacturing process: From sugar to sucralose

To understand why sweetener 955 is considered artificial, it is necessary to look at its production process. The journey from natural sugar to synthetic sucralose is a multi-step chemical conversion.

The chemical transformation

Sucralose begins as a sucrose (table sugar) molecule. Chemists then selectively replace three of the sucrose molecule's hydroxyl groups (hydrogen-oxygen groups) with three chlorine atoms. This specific alteration is key to sucralose's properties. The new chemical structure means that the human body's enzymes do not recognize sucralose as a carbohydrate. As a result, most of the sucralose passes through the body unabsorbed and is excreted, which is why it provides zero calories. The modified molecule is also significantly sweeter than its original form.

The multi-step process

  1. Preparation of sucrose-6-acetate: Sucrose is selectively protected by converting it to sucrose-6-acetate. This step is crucial for ensuring the subsequent chlorination happens at the correct locations.
  2. Chlorination: The sucrose-6-acetate is then exposed to a chlorinating agent, which replaces three specific hydroxyl groups with chlorine atoms. This occurs under carefully controlled conditions.
  3. De-esterification: The protective acetate group is removed from the molecule, leaving the final sucralose product.
  4. Purification: The resulting crude sucralose is purified and crystallized to achieve the high-purity, food-grade sweetener used in products.

Natural vs. artificial: A comparison of sweeteners

To highlight the differences between sweetener 955 (sucralose) and truly natural alternatives, it is useful to compare their key characteristics.

Aspect Sweetener 955 (Sucralose) Natural Sweeteners (e.g., Stevia)
Origin Derived from sucrose, but is an artificial (synthetic) compound. Extracted directly from plants, such as the Stevia rebaudiana plant leaves.
Processing Involves a multi-step chemical process with chlorination. Processed via extraction and purification methods, though commercial products may be refined.
Sweetness Approximately 600 times sweeter than table sugar. Extracts can be 200–400 times sweeter than sugar.
Calorie Content Zero calories, as it is not metabolized by the body. Zero calories from steviol glycosides.
Aftertaste Generally has a clean, sugar-like taste, though some people report a lingering sensation. Some versions can have a slight, sometimes licorice-like or bitter, aftertaste, which has been minimized in modern blends.
Heat Stability Highly stable and suitable for baking and cooking. Also very heat stable and can be used in baking.

Safety and controversies surrounding sucralose

Like many artificial sweeteners, sucralose has been the subject of debate regarding its long-term health effects. While regulatory bodies like the FDA and WHO have deemed it safe for consumption within an acceptable daily intake (ADI), conflicting research and anecdotal reports have fueled controversy.

Some of the key areas of concern include:

  • Gut microbiome disruption: Animal and some human studies have suggested that sucralose may alter the balance of gut bacteria, potentially leading to digestive issues. The impact appears to be dependent on dosage and duration.
  • Metabolic effects: While sucralose does not typically spike blood sugar, some research has linked artificial sweeteners to potential metabolic changes in certain individuals, especially those who do not regularly consume them. More high-quality research is needed to clarify these findings.
  • Heat-induced compounds: Some research has indicated that heating sucralose at high temperatures, particularly with other ingredients like fats, may produce potentially harmful compounds called chloropropanols. However, other studies have contested this, and health authorities continue to consider it safe for use in baking.

It is important to note that many studies highlighting negative effects use very high doses of sucralose, far exceeding what the average person would consume. The WHO recently published new guidance on non-sugar sweeteners, advising against their use for weight control in general, though this is a conditional recommendation and not specific to sucralose.

Natural alternatives to sweetener 955

For those who prefer to avoid artificial sweeteners, several plant-derived or natural alternatives are available:

  • Stevia: Extracted from the leaves of the stevia plant, this is a popular zero-calorie sweetener available in powder, liquid, and blended forms.
  • Monk fruit: Derived from the monk fruit, or luo han guo, this calorie-free sweetener is known for its intense sweetness and clean taste.
  • Erythritol: A sugar alcohol produced via the fermentation of corn, erythritol is low in calories and doesn't cause blood sugar spikes.
  • Xylitol: Another sugar alcohol derived from plants, it is known for being tooth-friendly and having a slight cooling sensation.

Conclusion: Is sweetener 955 for you?

Ultimately, sweetener 955, or sucralose, is an artificial substance, despite its origins from sucrose. The chemical modifications made during its production are what define it as synthetic, offering a zero-calorie, intensely sweet product. For many people, it is a safe and effective tool for reducing sugar intake, particularly for managing diabetes or body weight. However, its use has generated some health and safety debates, and conflicting research exists regarding its potential long-term impacts, particularly on gut health. When deciding whether to incorporate sucralose into your diet, it is important to consider these factors alongside your personal health goals. For a more complete understanding of non-sugar sweeteners, you can review the official guidance from health authorities like the World Health Organization (WHO Guidance on Non-Sugar Sweeteners).

As with any dietary choice, moderation is key. Alternatives like stevia and monk fruit offer natural options for those who prefer to avoid synthetic additives. Consulting with a healthcare professional or registered dietitian is the best way to determine the most suitable sweeteners for your individual health needs.

Frequently Asked Questions

Sucralose is the chemical name for sweetener 955, while Splenda is the brand name for a sucralose-based product. Tabletop Splenda products typically contain a small amount of sucralose mixed with bulking agents like dextrose and maltodextrin.

For most people, sucralose does not significantly affect blood sugar or insulin levels because it is not metabolized by the body. However, some studies in individuals not accustomed to consuming artificial sweeteners have shown some impact, and more research is needed.

Sucralose is heat-stable and widely used in baking. While some studies have raised concerns about potential compound formation when heated at very high temperatures, health authorities still consider it safe for cooking and baking purposes.

Sucralose is calorie-free, and some studies suggest using low-calorie sweeteners can aid in weight loss. However, some conflicting research indicates artificial sweeteners might increase appetite or cravings for sweet foods, potentially affecting weight in the long run.

Common side effects, particularly with excessive consumption, can include digestive issues such as bloating, gas, or diarrhea. Some people may also experience headaches.

Studies on the effect of sucralose on the gut microbiome are mixed. Some animal and long-term human studies suggest it could potentially disrupt the balance of gut bacteria, while short-term human studies have shown no significant effect.

Stevia is a natural alternative derived from a plant, whereas sucralose is artificial. For those who prioritize natural origins, stevia may be preferred. The "better" option depends on individual taste preferences and health goals.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.