Skip to content

What are the negatives of xanthan gum? Potential risks and side effects

5 min read

While the FDA generally recognizes xanthan gum as safe, consuming large quantities, typically over 15 grams per day, can lead to unpleasant digestive issues like gas and bloating. This potential for discomfort is one of the main concerns associated with the common thickening agent, especially for those with sensitive digestive systems.

Quick Summary

This article explores the potential adverse effects of xanthan gum, including common digestive side effects, allergic reactions linked to its production, and serious health risks for specific populations like premature infants. It also covers occupational hazards and highlights that most people consume far less than the amount needed to cause problems.

Key Points

  • Digestive Distress: High intake of xanthan gum can lead to significant gas, bloating, and abdominal pain due to its function as a soluble fiber.

  • Risks for Premature Infants: A thickener containing xanthan gum has been linked to a life-threatening intestinal condition (necrotizing enterocolitis) in premature infants, leading to FDA warnings.

  • Allergy Concerns: The fermenting substrate used to produce xanthan gum can come from common allergens like corn or soy, posing a risk for individuals with severe allergies.

  • Medication Interference: Large doses of xanthan gum can lower blood sugar, potentially interfering with diabetes medications and affecting absorption of other oral drugs.

  • Occupational Health Hazard: Inhaling xanthan gum powder, particularly in industrial settings, can cause respiratory irritation and flu-like symptoms.

  • Variable Tolerance: While safe for most in small amounts, those with existing digestive sensitivities like IBS may find even low doses cause discomfort.

In This Article

Common Digestive Problems Associated with Xanthan Gum

One of the most frequently reported side effects of xanthan gum consumption is gastrointestinal distress, particularly when ingested in large quantities. As a soluble fiber, xanthan gum is not digested by the body. Instead, it absorbs water and forms a gel-like substance in the digestive tract, which can have a laxative effect. While this property can help relieve constipation for some, excessive intake can lead to a range of uncomfortable symptoms. Studies have found that high doses, often exceeding 15 grams per day, can result in:

  • Increased intestinal gas and flatulence
  • Significant bloating and abdominal pain
  • Softer, bulkier, or increased frequency of bowel movements

These symptoms occur because the bacteria in the gut ferment the undigested soluble fiber, producing gas. While a typical diet contains a negligible amount of xanthan gum, supplementation or consumption of many processed foods could increase total intake and exacerbate these issues for sensitive individuals.

Risks for Specific Populations

While most healthy adults can tolerate xanthan gum without issue, certain groups should be more cautious:

Premature Infants

A serious and life-threatening condition called necrotizing enterocolitis (NEC), which involves inflammation and damage to the intestines, has been linked to a xanthan gum-based thickener used in infant formula for premature babies. The FDA has issued warnings against using such thickeners in this population due to the immaturity of their digestive systems. While the specific commercial product responsible is no longer recommended, it highlights a critical risk for this vulnerable group.

Individuals with Severe Allergies

Xanthan gum is produced through the fermentation of sugars by the bacterium Xanthomonas campestris. The sugar substrate can come from common allergens such as wheat, corn, soy, or dairy. While the finished product is highly processed, trace amounts of the source material may remain. Therefore, people with severe allergies to these foods should check with the manufacturer about the source of the gum or avoid it altogether to prevent a potential allergic reaction.

People with Diabetes on Medication

Consuming xanthan gum in larger doses, such as in supplements, can lower blood sugar levels. This can pose a risk for people with diabetes who are already taking blood sugar-lowering medication, as it could lead to dangerously low blood sugar levels (hypoglycemia). Anyone with diabetes should consult their doctor before using xanthan gum as a supplement.

Individuals with Intestinal Conditions

For those with existing gastrointestinal issues like Irritable Bowel Syndrome (IBS) or Inflammatory Bowel Disease (IBD), even small amounts of xanthan gum can trigger digestive discomfort, gas, and bloating. These individuals may find it beneficial to limit or avoid the additive to manage their symptoms. Research into the effects on the gut microbiome is still developing, but some evidence suggests additives like this could affect intestinal inflammation.

Occupational and Other Hazards

Beyond ingestion, exposure to xanthan gum powder carries its own set of risks. Workers who handle the dry powder in manufacturing or bakeries have reported respiratory and nasal irritation, as well as flu-like symptoms, from inhaling it. This highlights the importance of safe handling and adequate ventilation when working with the powdered form. Additionally, in rare cases, high consumption of xanthan gum has been linked to migraines and skin irritation in sensitive individuals.

Comparison Table: Xanthan Gum vs. Natural Thickeners

For those who wish to avoid xanthan gum, several natural alternatives offer similar thickening properties without the potential downsides. The choice depends on the specific application and dietary needs.

Feature Xanthan Gum Psyllium Husk Chia Seeds Arrowroot Flour
Origin Bacterial fermentation of sugars Husks of Plantago ovata seeds Salvia hispanica plant seeds Roots of the arrowroot plant
Digestive Effect Can cause bloating and gas in high doses High soluble fiber, aids digestion, may cause gas initially High soluble fiber, forms gel, aids digestion Easily digested, less likely to cause digestive upset
Allergy Concerns Potential for trace allergens (corn, soy, wheat) Generally low-allergen, derived from plants Generally low-allergen, but may trigger legume allergy Considered low-allergen and easily tolerated
Best For Gluten-free baking, salad dressings, sauces Breads, constipation relief, fiber supplements Puddings, thickeners, egg replacement Soups, sauces, and thickening at low temperatures

Conclusion: Navigating the Negatives

While xanthan gum is an effective and safe food additive for the majority of the population when consumed in typical food amounts, it is not without its negatives. For most people, the quantity in processed foods is too low to cause an issue, but a combination of consuming multiple products with the additive could lead to digestive discomfort. Awareness of potential digestive side effects like bloating and gas is crucial, especially for individuals with conditions like IBS or IBD. Additionally, specific at-risk populations, including premature infants and those with severe allergies to certain food sources, must exercise caution. By understanding these potential risks, consumers can make informed choices about their dietary needs and seek alternative thickeners when necessary. A sensible approach is to be mindful of total intake and listen to your body's response.

For more detailed health guidance, refer to authoritative sources like the Food and Drug Administration (FDA) website.

Nutritional and Dietary Context

For most individuals on a standard diet, the negatives of xanthan gum are minimal, and the amount consumed is typically far below any problematic threshold. In the context of a healthy diet, the focus should remain on consuming whole, unprocessed foods. However, in the realm of processed or gluten-free foods, xanthan gum plays a critical role. Understanding its properties allows those with sensitivities or specific health concerns to identify potential triggers and seek alternatives. The key is balance and awareness, rather than outright avoidance for everyone.

Addressing Allergy and Cross-Contamination Concerns

Because xanthan gum is created from fermented sugars, the source of these sugars is a primary concern for individuals with allergies. Manufacturers may not always specify the sugar's origin (e.g., corn, soy, wheat). While extensive processing removes most allergenic proteins, trace amounts can still be a risk for those with severe sensitivities. This is a particularly important negative for those with celiac disease, who must be certain their gluten-free products are truly free from contamination. This ambiguity necessitates diligent label reading and, in some cases, contacting the manufacturer directly.

The Digestive Trade-off

The soluble fiber nature of xanthan gum is both its biggest benefit and its main negative. On one hand, it can aid with constipation due to its bulking and water-absorbing properties. On the other, it is precisely this mechanism that can lead to excessive gas, bloating, and diarrhea in higher amounts. For people with existing digestive sensitivities, this bulk-forming effect can be overwhelming for their system, leading to discomfort. Unlike natural fibers that are part of a whole food, xanthan gum's isolated form can sometimes have a more pronounced and immediate effect on the intestines.

Who Should Avoid Xanthan Gum?

Based on potential negative effects, certain individuals should consider limiting or avoiding xanthan gum:

  • Premature infants due to the risk of necrotizing enterocolitis
  • Individuals with severe corn, soy, wheat, or dairy allergies unless the source is confirmed
  • People with IBS or IBD who experience digestive upset
  • Those on diabetes medication should consult a doctor before consuming large doses
  • Anyone prone to gas and bloating who has noticed symptoms after consuming products with xanthan gum

Frequently Asked Questions

Yes, especially in larger quantities, xanthan gum can cause gas and bloating. As a soluble fiber, it ferments in the large intestine, a process that can produce gas and lead to discomfort, particularly for those with sensitive digestive systems.

Yes, there is evidence that a xanthan gum-based thickener was linked to a serious intestinal disease called necrotizing enterocolitis in premature infants. For this reason, the FDA advises against giving these products to infants unless specifically approved by a healthcare provider.

If you have severe allergies to corn, wheat, soy, or dairy, you should be cautious. Xanthan gum's production process can involve fermenting sugars derived from these allergens, and though rare, trace amounts may remain and trigger a reaction.

Yes, xanthan gum can interfere with medication. It can lower blood sugar levels in larger doses, posing a risk for those on diabetes medication. Furthermore, its thickening properties can slow the absorption of oral drugs, so it is recommended to take it an hour before or after other medications.

Yes. Xanthan gum functions as a bulk-forming laxative by drawing water into the intestines, softening stool and increasing bowel movement frequency. Excessive intake can cause diarrhea or very soft stools.

For people with irritable bowel syndrome (IBS), xanthan gum may not be safe. The fermentation of this soluble fiber in the gut can lead to gas, bloating, and abdominal pain, exacerbating IBS symptoms even in low doses.

Yes, there is a risk associated with inhaling the powder. Individuals exposed to large amounts of xanthan gum powder, such as industrial workers, have reported respiratory irritation, flu-like symptoms, and nose and throat irritation.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.