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What are the side effects of active lactic culture?

4 min read

According to Healthline, a temporary increase in gas and bloating is the most commonly reported reaction when starting probiotic supplements that contain active lactic culture. Though generally safe, these microorganisms can cause some individuals to experience digestive discomfort as their gut flora adjusts.

Quick Summary

Exploring the potential side effects associated with active lactic culture, including common digestive issues like bloating and gas, along with serious risks for immunocompromised individuals.

Key Points

  • Initial Digestive Upset: Bloating and gas are common but temporary side effects when introducing active lactic culture, as the gut microbiome adjusts to the new bacteria.

  • Histamine Reactions: Certain probiotic strains can increase histamine levels, potentially causing allergy-like symptoms in sensitive individuals.

  • Food vs. Supplements: Biogenic amines in fermented foods, not just supplements, can trigger headaches in sensitive people.

  • Immune System Risk: Immunocompromised individuals face a rare but heightened risk of systemic infection from the live bacteria.

  • Start Small and Slow: Beginning with a lower dose and increasing gradually can minimize initial digestive discomfort and help the body adapt.

  • Listen to Your Body: If side effects persist beyond a few weeks, or if severe symptoms occur, it's crucial to consult a healthcare professional.

In This Article

Common Digestive Side Effects

The most frequent side effects of consuming active lactic culture, whether from fermented foods or supplements, are digestive. These symptoms often occur as the gut microbiome adjusts to the introduction of new bacteria and are typically mild and temporary.

Common digestive issues include:

  • Bloating and Gas: This is a very common initial reaction as the new bacteria ferment undigested carbohydrates, producing gas.
  • Stomach Upset and Pain: Some individuals may experience mild abdominal discomfort or cramping, especially when starting a new probiotic product.
  • Changes in Bowel Movements: Active lactic culture can affect bowel regularity. While it can help with diarrhea, some people might experience softer stools, temporary diarrhea, or even constipation initially.

For most healthy people, these effects should subside within a few days or weeks as the body adapts. Starting with a lower dose and gradually increasing it can help minimize this initial discomfort.

Less Common Reactions and Risks

Beyond basic digestive discomfort, a smaller percentage of the population may experience other side effects, often linked to pre-existing sensitivities or specific product ingredients.

  • Headaches from Biogenic Amines: Some fermented foods, such as certain yogurts, aged cheeses, and kimchi, naturally contain biogenic amines, which are substances formed during the fermentation process. In individuals sensitive to these compounds, consuming high-amine foods can trigger headaches or migraines.
  • Histamine Intolerance: Certain strains of lactic acid bacteria can produce histamine in the gut. For those with histamine intolerance, this can lead to allergy-like symptoms such as itching, hives, watery eyes, or a runny nose. Individuals with this intolerance may need to select specific low-histamine probiotic strains.
  • Ingredient-Based Allergies: Adverse reactions can sometimes be caused not by the active lactic culture itself, but by other ingredients in the supplement or food product. Common allergens to watch for include dairy, soy, egg, or gluten. Those with specific allergies should always check product labels carefully.
  • Exacerbation of SIBO Symptoms: In some cases, probiotics can worsen symptoms for people with Small Intestinal Bacterial Overgrowth (SIBO). Introducing new bacteria can cause increased gas, bloating, and brain fogginess in these individuals.

Who Should Be Cautious?

While active lactic culture is generally safe for the majority of people, certain populations are at a higher risk for serious complications and should consult a healthcare professional before use.

  • Immunocompromised Individuals: People with weakened immune systems due to conditions like HIV/AIDS, or those undergoing treatments like chemotherapy, face a rare but serious risk of developing infections from probiotic bacteria entering the bloodstream (bacteremia).
  • Patients with Serious Illnesses: Those with critical illnesses, prolonged hospitalizations, or indwelling venous catheters should be cautious. Studies have shown negative outcomes in some critically ill patients and those with severe acute pancreatitis.
  • Post-Surgery Patients: Individuals recovering from major surgery may be more susceptible to infections and should exercise caution with probiotics.
  • Individuals with Damaged GI Tracts: Patients with conditions affecting the integrity of the gastrointestinal tract, such as short bowel syndrome, should consult a doctor before taking active lactic culture.

Comparison of Benefits and Side Effects

Aspect Benefits of Active Lactic Culture Potential Side Effects Who is Affected?
Digestion Aids digestion, supports healthy gut flora, and may alleviate certain diarrheal conditions. Initial bloating, gas, stomach pain, or bowel changes. Most healthy individuals, often temporarily.
Immune System Can support immune function and reduce inflammation. Rare risk of infection if the immune system is severely compromised. Immunocompromised or critically ill individuals.
Specific Intolerances Can help manage lactose intolerance symptoms by breaking down lactose. Histamine-producing strains can cause allergy-like symptoms in sensitive people. Individuals with histamine intolerance.
Allergies May potentially help with certain allergic conditions like eczema in some cases. Allergic reactions to supplement ingredients (e.g., dairy, soy). Individuals with specific food allergies or intolerances.
Overall Health Associated with nutrient absorption and general well-being. Rare cases of serious infection in vulnerable populations. Immunocompromised, critically ill, or post-surgical patients.

Managing Potential Side Effects

If you experience side effects from active lactic culture, there are steps you can take to manage them effectively.

  • Start with a Low Dose: If taking a supplement, begin with a lower colony-forming unit (CFU) count and increase gradually over several weeks. For fermented foods, start with a smaller serving size.
  • Check Ingredients: Read supplement labels carefully to ensure there are no ingredients that you are allergic or intolerant to, such as soy, dairy, or gluten.
  • Consider Histamine Levels: If you are sensitive to histamine and experience headaches or allergy-like symptoms, research and choose probiotic strains known to be low in biogenic amines.
  • Monitor and Adjust: Pay attention to how your body reacts. If digestive issues are mild, they may resolve on their own. If symptoms are persistent, severe, or concerning, consider reducing your intake or switching products.
  • Consult a Professional: Always speak with a healthcare provider before starting a probiotic regimen, especially if you have an underlying health condition. This is critical for high-risk individuals. For more information on probiotic safety, consult reputable resources like the National Center for Complementary and Integrative Health (NCCIH).

Conclusion

Active lactic culture can provide significant health benefits, particularly for digestive and immune health, but it is not without potential side effects. For most healthy individuals, these are limited to temporary and mild digestive issues like gas and bloating as the body adjusts. However, people with compromised immune systems, severe illnesses, or specific intolerances must approach active lactic culture with caution and under medical supervision due to a rare but serious risk of infection or other complications. By understanding the potential downsides and taking proactive steps to manage intake and monitor your body's response, most can safely incorporate active lactic culture into their diet for improved well-being.

Frequently Asked Questions

Yes, bloating, gas, and mild stomach discomfort are common side effects when first taking active lactic culture. These symptoms usually occur as your gut adjusts and typically resolve within a few days or weeks.

For most healthy people, the initial digestive side effects, such as gas or bloating, are temporary and last for a few days to a few weeks as your gut flora rebalances.

In some cases, yes. Certain fermented foods that contain active lactic cultures also contain biogenic amines, which can trigger headaches in individuals who are sensitive to them.

People with weakened immune systems, severe illnesses, indwelling medical devices, or those recovering from major surgery should avoid active lactic culture supplements unless advised by a doctor, due to a rare risk of infection.

For the vast majority of healthy individuals, the risk of infection is very low. However, people who are critically ill or immunocompromised face a rare but more significant risk of systemic infection.

If side effects like bloating, gas, or other discomforts persist for more than a few weeks or become severe, you should stop taking the product and consult a healthcare professional.

The side effects are similar, but the risk factors can differ. Fermented foods, for example, can introduce biogenic amines that might trigger headaches, while some supplements contain allergens or prebiotics that can cause issues.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.