The use of stevia as a sugar substitute is popular due to its zero-calorie nature, but consuming too much can lead to adverse effects. The side effects largely depend on the form of stevia and the amount consumed. Highly purified steviol glycosides are considered safe by the FDA in moderation, while unpurified extracts are not approved. Side effects from purified stevia are minimal when consumed within acceptable limits, but risks increase with overconsumption or when products contain additional ingredients.
Digestive Problems from Stevia Overload
Digestive distress is a common issue with high stevia intake, often linked to sugar alcohols like erythritol and xylitol used as fillers in many products.
- Bloating and Gas: Sugar alcohols are fermented by gut bacteria, producing gas.
- Nausea and Diarrhea: High intake of sugar alcohols can cause a laxative effect.
Additionally, some research suggests purified stevia might alter the gut microbiome, potentially contributing to discomfort, though more human studies are needed.
Cardiovascular and Endocrine System Concerns
Preliminary studies suggest potential effects of high stevia intake on blood pressure and hormone levels.
Potential Drug Interactions
- Hypotension: Stevia may lower blood pressure. Excessive consumption could cause issues for those with low blood pressure or on blood pressure medication.
- Hypoglycemia: While pure stevia has minimal impact on blood sugar, fillers like dextrose can. Stevia's mild blood-sugar-lowering effect could also interact with diabetes medication.
Possible Endocrine Disruption
Concerns exist due to the structural similarity of steviol glycosides to steroid hormones, though human evidence of endocrine disruption from stevia is currently lacking.
Allergic Reactions and Other Side Effects
Allergic reactions are rare but possible, particularly for those sensitive to plants like ragweed. Symptoms can include rashes. Less common side effects include dizziness and numbness. Some research suggests a potential link between erythritol, a common additive, and increased risk of heart issues, but more study is needed.
Comparison: Types of Stevia and Additives
Understanding the different forms of stevia and accompanying additives is crucial. Only highly purified steviol glycosides have FDA GRAS status.
| Feature | Highly Purified Steviol Glycosides (e.g., Reb A) | Crude Stevia Extracts & Raw Leaves | Stevia Products with Additives |
|---|---|---|---|
| FDA Approval Status | Yes (GRAS) | No, insufficient safety data | Varies based on additives |
| Purity Level | >95% pure | Lower, unrefined | Varies, can be high-purity stevia with other ingredients |
| Common Side Effects | Minimal in moderation | Not well-documented, potentially higher risk | Digestive issues (bloating, gas, diarrhea) |
| Associated Risks | Possible drug interactions with very high intake | Concerns for kidney, cardiovascular, reproductive health | Increased blood sugar (dextrose/maltodextrin); possible cardiac risk (erythritol) |
Conclusion
While purified stevia is generally safe in moderation, excessive intake can lead to side effects, mainly digestive issues and potential drug interactions. These effects are often exacerbated by other ingredients like sugar alcohols in many products. Reading labels and staying within the ADI is important. Individuals with conditions like diabetes or low blood pressure should consult a healthcare provider. For official information, refer to the FDA's stance on food additives.