Stevia, derived from the leaves of the Stevia rebaudiana plant, has gained widespread popularity as a zero-calorie, natural-origin sweetener. Its use, however, is not without some reported downsides, and the full extent of its long-term effects is still under investigation. While the FDA has approved highly purified steviol glycosides as Generally Recognized as Safe (GRAS), less refined versions, such as whole leaves and crude extracts, do not have this approval. Therefore, it is important for consumers to be aware of the potential side effects, which range from mild digestive complaints to more serious medication interactions.
Gastrointestinal Issues
One of the most frequently cited side effects associated with stevia consumption is digestive discomfort. This is often not caused by the steviol glycosides themselves, but rather by other ingredients commonly added to commercial stevia products.
- Sugar Alcohols: Many stevia-based sweeteners contain sugar alcohols, such as erythritol, to add bulk and improve texture. For some people, consuming large amounts of these compounds can lead to gas, bloating, and diarrhea.
- Gut Microbiome Disruption: Some studies, primarily animal-based, have suggested that nonnutritive sweeteners like stevia could potentially alter the gut microbiome. While research in humans is ongoing and results are mixed, an imbalance in gut bacteria could theoretically contribute to digestive problems.
- Nausea: Individuals may experience nausea, especially when consuming higher doses of stevia. This is believed to be a symptom of general intolerance rather than a serious health risk.
Potential Allergic Reactions
Although allergic reactions to stevia are rare, they are a possibility, particularly for those with pre-existing plant sensitivities.
- Ragweed Family Sensitivity: The stevia plant is a member of the Asteraceae family, which also includes common allergens like ragweed, chrysanthemums, and daisies. Individuals with an allergy to these plants may experience a cross-reactive allergic reaction to stevia.
- Symptoms: Reactions can range from mild symptoms like itching or tingling in the mouth to more severe issues such as swelling or difficulty breathing in very rare cases.
- Purity Matters: Highly refined stevia extracts are less likely to trigger an allergic response, as the proteins that cause the reaction are mostly removed during processing. However, less refined or homemade preparations carry a higher risk.
Effects on Blood Pressure and Blood Sugar
Stevia's effects on blood pressure and blood sugar are a double-edged sword, with both potential benefits and risks depending on an individual's health status.
- Lowered Blood Pressure: Stevia has been shown to have a blood pressure-lowering effect by acting as a vasodilator, widening the blood vessels. While beneficial for those with hypertension, it could potentially cause issues like dizziness or fatigue for individuals with naturally low blood pressure.
- Hypoglycemia Risk: As stevia can help lower blood sugar levels, it can enhance the effects of diabetes medication. This may lead to dangerously low blood sugar (hypoglycemia) if not monitored carefully by a doctor.
- Product Additives: Some stevia products contain dextrose or maltodextrin, which can slightly increase carbohydrate and calorie content. While minimal in small quantities, frequent use can impact blood sugar levels for people with diabetes.
Other Considerations and Concerns
Besides the primary side effects, there are other considerations to keep in mind when using stevia.
- Aftertaste: Many people report a lingering, often licorice-like or bitter, aftertaste, especially in higher concentrations. Finding the right brand or a blended product can sometimes help mitigate this issue.
- Medication Interactions: Beyond diabetes medication, stevia can interact with other drugs. Its diuretic effect can affect how the body excretes lithium, potentially leading to dangerous accumulation.
- Endocrine Concerns: Some early animal research suggested a potential for stevia to disrupt hormones. However, more recent evaluations by regulatory bodies have found no evidence of reproductive toxicity in mammals at normal consumption levels.
- Pregnancy and Children: While highly purified stevia is considered safe for pregnant women and children within the Acceptable Daily Intake (ADI), consultation with a healthcare provider is recommended. Whole stevia leaf and crude extracts are not approved for consumption.
Stevia vs. Other Sweeteners: A Comparison
To put stevia's side effects into perspective, it's helpful to compare it with other common sweeteners.
| Feature | Stevia | Artificial Sweeteners (e.g., Aspartame, Sucralose) | Sugar Alcohols (e.g., Erythritol) | 
|---|---|---|---|
| Source | Natural, plant-based extract | Synthetically produced chemical compounds | Naturally found but commercially produced from fermented starch | 
| Calorie Content | Zero calories | Zero calories | Minimal calories | 
| Effect on Blood Sugar | Negligible impact on blood glucose, but depends on product additives | No impact, but some associated health risks exist | Can have minimal impact, but can cause digestive issues | 
| Common Side Effects | Digestive issues (often due to additives), rare allergies, aftertaste | Potential links to gut health disruption, heart disease, aftertaste | Gastrointestinal distress (gas, bloating, diarrhea) with high intake | 
| FDA Status | High-purity extracts are GRAS; crude extracts are not | Approved, but with some lingering health debates and concerns | GRAS status | 
Conclusion
While the FDA has given high-purity stevia leaf extracts a clean bill of health for moderate use, it is not entirely free of potential side effects. Many of the common complaints, such as digestive issues, are often caused by the additional ingredients like sugar alcohols present in commercial products. For those with specific health conditions like low blood pressure or diabetes, or sensitivities to certain plants, it is especially important to proceed with caution and consult a healthcare professional. Ultimately, understanding product purity and individual tolerance are key to navigating the potential side effects of using stevia effectively. As with any dietary choice, moderation remains a key factor.
How to Find a Pure Stevia Product
When buying stevia, always read the ingredient list carefully. Look for products that list only "stevia leaf extract" or "steviol glycosides" and explicitly avoid fillers like dextrose, maltodextrin, or other sugar alcohols. Purchasing pure, unadulterated stevia powder or liquid extract can help minimize the risk of digestive issues caused by these additional ingredients. Additionally, opting for a well-known brand with a transparent ingredient list can offer more assurance of product purity.