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What is Another Name for Rutin? A Complete Guide to Rutoside and Vitamin P

3 min read

Over 6,000 types of flavonoids have been identified in plants, and one of the most well-known is rutin, also known as rutoside. This powerful plant pigment, once mistakenly classified as a vitamin, is a glycoside combining the flavonol quercetin with the disaccharide rutinose.

Quick Summary

This article explores the multiple names for the plant flavonoid rutin, detailing its chemical structure, common sources, historical context, and benefits for vascular health and antioxidant support.

Key Points

  • Multiple Names: Rutin is also known as rutoside, quercetin-3-O-rutinoside, and historically as vitamin P.

  • Antioxidant Power: Rutin acts as a potent antioxidant, helping to neutralize harmful free radicals and reduce oxidative stress.

  • Vascular Support: A key benefit of rutin is its ability to strengthen blood vessel walls and improve circulation, which can aid in conditions like varicose veins and hemorrhoids.

  • Rich Food Sources: Excellent dietary sources of rutin include buckwheat, citrus fruits (especially the peel), apples, black and green tea, and asparagus.

  • Rutin vs. Quercetin: Rutin is a glycoside that contains the aglycone quercetin. Some studies suggest quercetin may have higher bioavailability and biological activity in some cases after rutin is metabolized.

  • Historical Context: The term 'vitamin P' is an outdated label for flavonoids, as these compounds are not considered true vitamins.

In This Article

Common Synonyms and Chemical Names for Rutin

As a widely researched flavonoid, rutin goes by several other names in both scientific and common parlance. The most frequently used alternative names are rutoside and quercetin-3-O-rutinoside. Historically, it was also referred to as vitamin P, though this name is outdated as flavonoids are not true vitamins.

  • Rutoside: This is a primary scientific synonym for rutin, often used in pharmacological and nutritional studies.
  • Quercetin-3-O-rutinoside: This is the precise chemical name, which describes its molecular structure as a combination of the flavonol quercetin and the disaccharide rutinose.
  • Sophorin: Another less common synonym for rutin.
  • Vitamin P: A historical term used in the 1930s when flavonoids were first discovered and thought to be essential vitamins, but it is no longer scientifically accurate.

The Historical Misnomer of Vitamin P

The term 'vitamin P' originated from early studies into the compound's effect on vascular permeability, or the 'P' for permeability. While flavonoids were initially classified alongside true vitamins, it was later discovered that they do not meet the criteria for essential nutrients that the body cannot synthesize. Despite this reclassification, the term 'vitamin P' persists in some circles as a historical reference to bioflavonoids, the broader category to which rutin belongs.

Sources of Rutin and Its Benefits

Rutin is a natural plant pigment found in a wide variety of foods. Its presence is often indicated by the vibrant colors of fruits and vegetables. By incorporating more of these foods into your diet, you can increase your intake of this beneficial bioflavonoid.

Comparison Table: Rutin Sources and Associated Benefits

Source Rutin Concentration Associated Health Benefits
Buckwheat High, especially in Tartary buckwheat Supports cardiovascular and circulatory health
Apples (especially unpeeled) Moderate to high Antioxidant properties, helps with vitamin C absorption
Black and Green Tea Moderate Antioxidant and anti-inflammatory effects
Asparagus Moderate Provides antioxidant support
Citrus Fruits (peel and pith) High Supports vascular integrity and circulation
Figs Moderate Antioxidant properties

The Health-Supporting Properties of Rutin

Rutin's primary health benefits are linked to its potent antioxidant and anti-inflammatory effects. By scavenging harmful free radicals, it helps protect cells from damage and reduces oxidative stress throughout the body.

Circulatory Health and Vascular Support

One of the most notable benefits of rutin is its positive impact on circulation and blood vessel health. It is thought to strengthen capillary walls, which can be beneficial for conditions such as:

  • Varicose Veins: Studies suggest that rutin may help improve blood circulation and reduce the symptoms of varicose veins, such as leg edema.
  • Hemorrhoids: Rutin has been used to help relieve the pain, swelling, and bleeding associated with hemorrhoids by strengthening fragile blood vessels in the rectal area.
  • Diabetic Retinopathy: For those with diabetes, rutin may protect and stabilize the retinal blood vessels damaged by high blood sugar.

Anti-Inflammatory and Other Effects

Beyond circulatory health, rutin's anti-inflammatory properties have shown promise in other areas of research. It has been explored for its potential role in managing conditions related to chronic inflammation. Its ability to deactivate inflammation-causing enzymes provides a mechanism for its potential therapeutic effects.

Bioavailability and Supplemental Forms

It is important to note that the bioavailability of rutin can be low due to poor absorption and rapid metabolism. This can be a consideration when consuming it via supplements versus whole food sources. Some research suggests that the aglycone component, quercetin, which is produced when rutin is broken down, may have higher biological activity in certain contexts. Supplements often contain either rutin or quercetin, and their absorption can sometimes be enhanced when taken with a meal containing fat or oil. Always consult a healthcare provider before taking any new supplement.

Conclusion: More Than Just a Name

What is another name for rutin? The answer is more complex than a single word. Rutin is also known as rutoside, quercetin-3-O-rutinoside, and was once called vitamin P. Each name tells a part of its story, from its precise chemical composition to its historical context in nutritional science. As a powerful bioflavonoid, its primary reputation comes from its ability to strengthen blood vessels and provide antioxidant support, with a variety of potential health benefits associated with its anti-inflammatory properties. Whether sourced from foods like buckwheat and apples or taken as a supplement, understanding its different names is key to appreciating this valuable plant compound.

Optional Outbound Link: For a detailed scientific review on the pharmacological potential of rutin, you can consult research available on the National Institutes of Health website.

Frequently Asked Questions

Rutin was once called vitamin P because early research suggested it was a new type of vitamin based on its ability to affect vascular permeability, with 'P' standing for permeability. However, this classification was later deemed incorrect because it is not an essential nutrient for humans.

There is no difference between rutin and rutoside; they are simply two different names for the same chemical compound. Rutoside is another scientifically accepted name for the flavonoid, frequently used in pharmacological literature.

Rutin is a glycoside that is composed of the flavonol quercetin and the disaccharide rutinose. Essentially, quercetin is the active molecular component released when rutin is metabolized in the body.

Some studies in animal models have indicated that rutin may help prevent thrombosis by inhibiting protein disulfide isomerase (PDI), a compound involved in blood clot formation. However, more research is needed to fully understand this effect in humans.

Buckwheat is one of the richest dietary sources of rutin, particularly Tartary buckwheat. Capers also contain a high concentration of rutin.

Yes, it is possible to find supplements containing both rutin and quercetin, as they are closely related compounds. It is always recommended to consult a healthcare professional before starting any new supplement regimen.

When consumed in amounts typically found in foods, rutin is considered safe. When taken in supplement form, some people have reported minor side effects such as headaches, flushing, skin rashes, or upset stomach.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.