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What is LCS Probiotic and How Does It Benefit Your Gut?

4 min read

First isolated and cultured in 1930 by Japanese scientist Dr. Minoru Shirota, the LCS probiotic is a specific, well-researched strain with documented health benefits. Today, this particular probiotic is a key ingredient in popular fermented milk drinks designed to support human gut health.

Quick Summary

This article explores the details of the LCS probiotic, also known as Lacticaseibacillus paracasei Shirota, including its origins, unique features that ensure its survival in the digestive tract, and the various documented health benefits it provides.

Key Points

  • Name and Classification: The LCS probiotic is the specific strain Lacticaseibacillus paracasei Shirota, formerly known as Lactobacillus casei Shirota.

  • Superior Survival: It is a highly resilient strain, specially cultivated to survive the journey through the stomach's acid and bile to reach the intestines alive.

  • Digestive Regularity: Regular consumption helps regulate bowel movements and improves stool consistency for both constipation and loose stools.

  • Immune Enhancement: LCS has been shown to boost immune function by increasing the activity of Natural Killer (NK) cells.

  • Common Source: The most popular source of this probiotic is the fermented milk drink Yakult, which contains billions of the live LCS strain.

  • Stress Relief: It can help mitigate stress-related abdominal discomfort and preserve gut microbiota diversity.

In This Article

Understanding the LCS Probiotic

At its core, the LCS probiotic refers to the specific bacterial strain Lacticaseibacillus paracasei Shirota, which was famously developed and commercialized by the Yakult company. For decades, it was known as Lactobacillus casei Shirota (LcS), but it underwent a taxonomic reclassification in 2020 along with several other members of the Lactobacillus genus. Despite the name change, its properties and benefits remain the focus of extensive research worldwide.

The Historical Discovery of LCS Probiotic

The story of LCS begins with Dr. Minoru Shirota, a microbiologist who, during the 1930s, was driven by the idea that a healthy gut was crucial for a long life. He devoted his research to studying lactic acid bacteria and successfully isolated and strengthened the unique strain known today as Lacticaseibacillus paracasei Shirota. This breakthrough led to the development of a fermented milk drink containing the probiotic, a product that would eventually be distributed globally.

Survival: The Key to Probiotic Efficacy

One of the most important characteristics distinguishing a truly effective probiotic is its ability to survive the highly acidic environment of the stomach and the bile-rich conditions of the small intestine to reach the lower gut alive. Many probiotic strains in food and supplements are not designed to withstand these harsh conditions, rendering them less effective. The LCS strain is specifically cultivated for its superior resilience, allowing it to colonize the intestines where it can provide its health benefits. Research has demonstrated that a significant number of viable LCS bacteria can be recovered from fecal samples after ingestion, confirming its survivability through the gastrointestinal (GI) tract.

Health Benefits of the LCS Probiotic

The consumption of the LCS probiotic has been linked to a number of health benefits, primarily concentrated in the gastrointestinal and immune systems.

Improved Digestion and Bowel Function:

  • Regulates bowel movements: Studies involving individuals with both constipation and loose stools have shown that regular intake of LCS can help regulate bowel movements and improve stool consistency.
  • Addresses gut infections: LCS has been investigated for its role in mitigating diarrhea caused by infections from pathogens like Clostridium difficile and Helicobacter pylori.
  • Supports gut microbial balance: By increasing beneficial bacteria and reducing potentially harmful ones, LCS contributes to a healthier, more balanced gut microbiota.

Immune System Modulation:

  • Enhances NK cell activity: Natural Killer (NK) cells are a key component of the innate immune system. LCS has been shown to increase the activity of these cells, which are crucial for destroying virus-infected and cancerous cells.
  • Regulates cytokines: LCS influences the production of various cytokines, which are signaling molecules of the immune system. This includes promoting T cell activation and modulating inflammatory responses.
  • Reduces infection risk: Studies have indicated that LCS intake may reduce the incidence and duration of upper respiratory tract infections in healthy adults and improve outcomes in children with pneumonia.

Beyond the Gut:

  • Liver support: In animal studies, LCS has been shown to protect against acute liver injury by reshaping the gut microbiota and modulating metabolic and inflammatory pathways.
  • Stress and mood relief: Research on students experiencing academic stress found that fermented milk containing LCS helped preserve gut microbiota diversity and relieved associated abdominal dysfunction.

LCS Probiotic vs. Other Common Probiotic Strains

Feature LCS (Lacticaseibacillus paracasei Shirota) Lactobacillus rhamnosus GG (LGG) Bifidobacterium lactis (HN019)
Origin Isolated by Dr. Minoru Shirota in 1930. Isolated in 1985 by Sherwood Gorbach and Barry Goldin. Isolated from a yogurt culture in the early 1990s.
Primary Use Digestive regulation, immune support, stress relief. Broad spectrum gut health, diarrhea management. Immune enhancement, particularly in the elderly.
GI Tract Survival Known for superior resistance to stomach acid and bile. Excellent survival rates and documented resistance. Demonstrated ability to survive the GI tract.
Immune Effects Modulates innate and specific immunity, enhances NK cell activity. Enhances mucosal immunity and gut barrier function. Stimulates phagocytosis and enhances immune function.
Format Most commonly found in fermented milk drinks like Yakult. Available in various fermented foods, capsules, and powders. Found in dairy products and dietary supplements.

How to Incorporate LCS Probiotic into Your Diet

The most common and reliable source of the LCS probiotic is the fermented milk drink Yakult, which contains billions of live Lacticaseibacillus paracasei Shirota in every bottle. For best results, consistency is key, as the probiotic does not colonize the gut indefinitely and requires regular consumption to maintain its presence. For individuals with specific health concerns, it is always recommended to consult a healthcare provider before starting any new supplement or dietary regimen.

Conclusion

The LCS probiotic is a highly resilient and effective bacterial strain with a long history of use and robust scientific research to back its claims. Its documented benefits for digestive health and immune function, coupled with its proven survivability through the gastrointestinal tract, make it a distinguished member of the probiotic world. Regular consumption, often through fermented milk products like Yakult, is a simple and effective way to help maintain a healthy gut and overall well-being.

For additional scientific insights, one can explore the in-depth research on LcS's impact on inflammation and gut microbiota via a study published in the journal Frontiers in Nutrition.

Frequently Asked Questions

LCS stands for Lacticaseibacillus paracasei Shirota, a specific and well-researched probiotic bacterial strain. It is often referred to as LcS and was previously classified under the name Lactobacillus casei Shirota.

The most widely known product containing the LCS probiotic is the fermented milk drink Yakult. Each bottle of Yakult contains billions of live Lacticaseibacillus paracasei Shirota.

The LCS probiotic is specifically cultivated to be highly resistant to the low pH of stomach acid and the bile salts present in the small intestine. This resilience allows a large proportion of the bacteria to survive and reach the gut alive, where it can provide its benefits.

LCS probiotic is generally considered safe for most healthy individuals, including children over one year old, and has been used safely in various studies. However, people with weakened immune systems or damaged heart valves should consult a doctor before taking any probiotic.

Yes, research indicates that the LCS strain can help regulate intestinal function. Studies have shown improvements in stool consistency and frequency for individuals experiencing both constipation and loose stools with regular consumption.

The beneficial effects of the LCS probiotic depend on consistent intake. When consumption is stopped, studies show that the gut microbiome tends to return to its baseline state within a few weeks to a month, indicating that regular consumption is needed to sustain the positive changes.

In 2020, the genus Lactobacillus was reclassified into 25 new genera, including Lacticaseibacillus. The strain formerly known as Lactobacillus casei Shirota was reclassified as Lacticaseibacillus paracasei Shirota. The difference is a new scientific name to reflect updated taxonomy, but the strain's properties are the same.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.