Who should be cautious with flaxseed?
Despite its many benefits, flaxseed is not suitable for everyone. Several conditions and circumstances warrant caution or complete avoidance of flaxseed. Consulting a healthcare provider is always recommended before adding significant amounts of flaxseed to your diet, especially if you have pre-existing health conditions or are taking medications.
Individuals with a bowel obstruction or stricture
Flaxseed contains a high amount of soluble fiber, which absorbs water and forms a gel-like substance in the digestive tract. While this property is excellent for relieving constipation for most, it can be hazardous for individuals with a bowel obstruction, a narrowed esophagus, or other intestinal narrowing. In these cases, the bulking effect of flaxseed can worsen the blockage, potentially leading to a medical emergency. The risk is particularly high if the flaxseed is consumed with insufficient fluids.
People on certain medications
Flaxseed can interact with various medications, altering their effectiveness. Its high fiber content can hinder the absorption of orally administered drugs if taken at the same time. To mitigate this, medications should be taken at least one to two hours before or after consuming flaxseed. More specific drug interactions also exist:
- Blood thinners (anticoagulant/antiplatelet drugs): Flaxseed can slow blood clotting, so combining it with medications like warfarin (Coumadin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of bleeding.
- Diabetes medications (antidiabetes drugs): Flaxseed may lower blood sugar levels. Taking it alongside medications for diabetes, such as insulin or metformin, could cause blood sugar to drop too low (hypoglycemia). Blood sugar should be monitored closely.
- Blood pressure medications (antihypertensive drugs): Flaxseed can reduce blood pressure. If you are already taking medication for high blood pressure, adding flaxseed could cause it to drop too low.
- Estrogen-containing drugs: The lignans in flaxseed act as phytoestrogens, mimicking the hormone estrogen. This can reduce the effectiveness of oral contraceptives and hormone replacement therapies.
Individuals with hormone-sensitive conditions
Because flaxseed contains phytoestrogens, its consumption can be a concern for individuals with hormone-sensitive conditions. While research is conflicting and some studies suggest a protective effect, the estrogenic activity could potentially worsen certain conditions. It is best to exercise caution and discuss with a doctor if you have:
- Breast, uterine, or ovarian cancer
- Endometriosis
- Uterine fibroids
Pregnant and breastfeeding women
The hormonal effects of flaxseed’s lignans raise concerns for pregnant and breastfeeding women, though the evidence is not conclusive. Some healthcare providers recommend avoiding flaxseed during pregnancy, particularly in large amounts. Flaxseed oil, in particular, has been linked to a potentially increased risk of premature birth in the second and third trimesters. While some health organizations do not advise against it, moderation and consultation with a doctor are prudent. The safety for breastfeeding mothers is less studied, so a cautious approach is often recommended.
Potential side effects and how to avoid them
Even for those without contraindications, improper consumption can lead to side effects. These can often be managed by adjusting dosage and preparation.
Digestive upset and dehydration
- Bloating and gas: Introducing too much fiber too quickly can cause digestive discomfort. It is best to start with small doses, such as a teaspoon of ground flaxseed daily, and gradually increase intake.
- Constipation or diarrhea: The high fiber can either worsen constipation or cause diarrhea, depending on the amount consumed and fluid intake. To prevent this, ensure you drink plenty of water when consuming flaxseed.
The risk of raw or unripe flaxseed
Raw and unripe flaxseeds contain compounds known as cyanogenic glycosides, which can release hydrogen cyanide. While the body can neutralize small amounts, high levels can be toxic. Roasting or cooking flaxseed before consumption can significantly reduce its cyanogenic content. It is always best to consume ground or roasted flaxseed rather than raw.
Flaxseed vs. Flaxseed Oil: A comparison
Flaxseed and flaxseed oil, while derived from the same source, offer different nutritional profiles and present unique considerations for consumption.
| Feature | Ground Flaxseed | Flaxseed Oil | 
|---|---|---|
| Fiber Content | High (both soluble and insoluble) | None | 
| Lignan Content | High | Low or none, depending on processing | 
| Omega-3s (ALA) | Good source, but less concentrated than oil | Excellent, highly concentrated source | 
| Digestion | Fiber can regulate digestion but requires ample fluid | No fiber, does not impact bowel bulk | 
| Hormonal Effects | Phytoestrogens can mimic estrogen | May have mild hormonal effects | 
| Cooking Suitability | Can be baked into goods | Sensitive to heat; not for cooking, add to finished dishes | 
| Storage | Ground seeds can go rancid quickly; store in fridge | Very sensitive to oxidation; must be refrigerated in dark bottle | 
Conclusion
Flaxseed is a powerful nutritional supplement for most people, but it is not without its risks. When should you not eat flaxseed? The answer is clear for those with intestinal blockages, those on specific medications, and individuals with hormone-sensitive conditions or pregnancy concerns. Even for healthy individuals, moderate intake combined with sufficient fluids and the use of ground or cooked seeds is the safest approach. Always consult a healthcare professional to ensure flaxseed is a safe and beneficial addition to your diet. For more information on dietary choices, consult reliable sources such as the National Institutes of Health (NIH) and other reputable medical organizations.