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Which e-numbers are harmful? Navigating the complexities of food additives

4 min read

According to the World Health Organization (WHO), while food additives are assessed for safety, overconsumption of highly processed foods and individual sensitivities can lead to health concerns. Understanding which e-numbers are harmful is therefore crucial for consumers to make informed dietary choices, moving beyond the misconception that all are unsafe.

Quick Summary

This article explores specific food additives associated with health concerns, including hyperactivity, allergic reactions, and other potential risks. It outlines how to identify and be cautious of certain E-numbers found in processed products.

Key Points

  • Not all E-numbers are harmful: Many are naturally derived or safe, but certain additives have been linked to potential health risks, requiring caution.

  • Hyperactivity links: Some artificial colors, notably E102, E110, and E129, have been associated with increased hyperactivity in some children.

  • Hidden risks in preservatives: Preservatives like sodium benzoate (E211) and sulphites (E220-E228) have been linked to hyperactivity, allergic reactions, and other adverse effects.

  • Emulsifiers and heart health: Studies suggest that a high intake of certain emulsifiers, including E471 and E472, may be linked to an increased risk of cardiovascular disease.

  • Artificial sweeteners and flavor enhancers: Additives like aspartame (E951) and MSG (E621) can cause issues for sensitive individuals, although scientific consensus on wider risks is debated.

  • Strategy for avoidance: Reducing consumption of ultra-processed foods and reading labels are the most effective ways to limit exposure to potentially harmful E-numbers.

In This Article

The purpose and regulation of E-numbers

E-numbers are codes assigned to food additives that have been approved for use within the European Union (EU) and other regions. The 'E' stands for Europe, and these numbers serve to standardize and simplify the labeling of additives across international markets. The regulatory process, overseen by bodies like the European Food Safety Authority (EFSA) and the Joint FAO/WHO Expert Committee on Food Additives (JECFA), involves extensive testing to determine an Acceptable Daily Intake (ADI). An E-number's presence on an ingredient list indicates that at one point it was considered safe for consumption under specific conditions. However, safety evaluations can evolve, and new research has flagged some additives as a cause for concern, particularly for sensitive individuals or when consumed in excess.

Controversial artificial colorants

Some of the most widely scrutinized E-numbers are artificial food colors, largely due to their link with hyperactivity in children. A landmark UK Food Standards Agency (FSA) funded study found that a mixture of artificial colors could cause increased hyperactivity in some children. As a result, many products in the EU containing these dyes must carry a warning label.

E-numbers linked to hyperactivity

  • E102 (Tartrazine): A lemon-yellow dye found in soft drinks, sweets, and sauces. Linked to hyperactivity and allergic reactions in sensitive individuals, especially those with asthma. Banned in some countries.
  • E110 (Sunset Yellow FCF): An orange-yellow colorant used in candy, drinks, and desserts. Associated with hyperactivity and skin reactions.
  • E122 (Carmoisine): A synthetic red dye. Some studies suggest it can trigger allergic reactions and worsen asthma symptoms.
  • E129 (Allura Red AC): A red dye. Best avoided by those with asthma or allergies.

Preservatives and their potential side effects

Preservatives, coded in the E200-E299 range, are added to foods to inhibit the growth of microorganisms and extend shelf-life. However, some have been associated with adverse health effects.

  • E211 (Sodium Benzoate): A preservative commonly found in soft drinks and dressings. Can form benzene, a carcinogen, when combined with vitamin C. It is also linked to hyperactivity in children.
  • E220-E228 (Sulphites): These preservatives are used in wine, dried fruit, and juices. They are a common cause of allergic reactions, particularly for asthmatics, and can cause symptoms like nausea and gastrointestinal upset.
  • E250 (Sodium Nitrite): Used to preserve cured meats like bacon and ham, and gives them a pink color. Can form carcinogenic nitrosamines during cooking at high temperatures.

Concerns with antioxidants, emulsifiers, and sweeteners

Antioxidants (E300-E399)

Synthetic antioxidants are used to prevent fats from becoming rancid. BHA (E320) and BHT (E321) are controversial synthetic antioxidants. BHA is classified as a possible human carcinogen by the International Agency for Research on Cancer. Some studies raise concerns about BHT's effects on hormone function.

Emulsifiers (E400-E499)

Recent research has brought emulsifiers under scrutiny for their potential impact on gut health and cardiovascular disease. A study published in The BMJ indicated that high intake of certain emulsifier E-numbers, such as monoglycerides and diglycerides of fatty acids (E471) and their esters (E472), was associated with an increased risk of cardiovascular disease. Carrageenan (E407), a thickening agent, has been linked to gastrointestinal inflammation.

Sweeteners (E900-E999)

Artificial sweeteners are a frequent subject of debate regarding their long-term health effects.

  • E951 (Aspartame): One of the most controversial sweeteners. While deemed safe at approved levels, some individuals report side effects like headaches and nausea. Concerns exist regarding potential neurological and metabolic effects, though scientific evidence is debated.
  • E621 (Monosodium Glutamate - MSG): A flavor enhancer that can cause adverse reactions like headaches, flushing, and palpitations in some individuals sensitive to it.

Comparison of notable controversial E-numbers

E-Number Category Associated Concern Common Product Examples
E102 Colorant Hyperactivity, allergies, asthma Soft drinks, mustard, sweets
E211 Preservative Hyperactivity, potential benzene formation Soft drinks, pickles, salad dressings
E320 Antioxidant Possible carcinogen, hormonal effects Chips, processed meats, cereals
E407 Emulsifier/Thickener Gastrointestinal inflammation Dairy alternatives, processed meats, ice cream
E621 Flavor Enhancer 'MSG symptom complex' (headaches, nausea) Instant noodles, crisps, savory snacks
E951 Sweetener Potential neurological effects in sensitive people Diet sodas, sugar-free gum, some desserts

How to avoid potentially harmful E-numbers

The key to minimizing exposure is to reduce consumption of ultra-processed foods. Here are some practical steps:

  1. Read ingredient labels carefully: Check for E-numbers, especially those in the controversial categories like artificial colors (E100s), preservatives (E200s), and certain emulsifiers (E400s). Be aware that some countries list the chemical name instead of the E-number.
  2. Choose whole foods: Opt for fresh, unprocessed ingredients that are naturally free from additives. The more a food is processed, the more likely it is to contain additives to enhance taste, texture, and shelf life.
  3. Use whole food alternatives: Instead of flavored packets with MSG (E621), use natural spices and herbs. Choose dried fruits without added sulphites (E220-E228) and prepare fresh juice instead of relying on packaged options with preservatives.
  4. Buy organic: Organic products generally prohibit the use of artificial additives and preservatives, although it's still wise to check labels for any specific additives that may be permitted in organic products.
  5. Cook at home: Preparing meals from scratch gives you complete control over ingredients and eliminates the need for many preservatives, flavor enhancers, and other additives common in pre-packaged foods.

Conclusion

While regulatory bodies like the JECFA and EFSA deem approved E-numbers safe within specified limits, evidence suggests that some additives carry potential risks, particularly for vulnerable groups like children or those with sensitivities. Additives linked to hyperactivity, allergic reactions, and gut inflammation, as well as those with potential carcinogenic implications, warrant caution. For consumers, the best approach is informed vigilance. By carefully reading labels and prioritizing a diet rich in whole, unprocessed foods, you can effectively manage and limit your intake of potentially harmful E-numbers. Limiting ultra-processed foods is a public health recommendation that reduces exposure to many non-essential and controversial additives.

World Health Organization fact sheet on food additives

Frequently Asked Questions

No, not all E-numbers are harmful. The E-number system is a standardized way of labeling approved food additives, which also includes naturally derived substances like Vitamin C (E300). Many E-numbers are considered safe, but a select few have been linked to potential health issues, especially in sensitive individuals.

If you have asthma or allergies, you should be particularly cautious of sulphites (E220-E228), which are known to trigger reactions in sensitive individuals. Some artificial colorants like tartrazine (E102) and carmoisine (E122) are also linked to asthma symptoms and allergic reactions.

Certain artificial food colors, such as E102, E104, E110, E122, E124, and E129, have been linked to increased hyperactivity in some children. As a result, products containing these dyes in the EU must carry a warning label.

Yes, Monosodium Glutamate is also known as E621 and is a flavor enhancer. While generally recognized as safe, some individuals are sensitive to it and may experience symptoms like headaches, flushing, and nausea, often called 'MSG symptom complex'.

The regulation and permitted use of E-numbers can differ significantly between regions. An additive banned in one country may be permitted in another. For example, some colorants are banned in Norway but still used in the UK. It's important to check the specific regulations and labeling in your country.

A 2023 study published in The BMJ associated high intake of certain emulsifier E-numbers, such as E471 and E472, with an increased risk of cardiovascular disease. Other studies have also suggested links to gut inflammation.

The most effective method is to reduce your consumption of ultra-processed foods, which are the primary source of many controversial additives. Opting for whole, unprocessed foods and cooking meals from scratch allows you to control all ingredients and naturally minimize your intake of E-numbers.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.