Understanding the Synergy of Lactobacillus and Saccharomyces
The gut microbiome is a complex ecosystem of microorganisms, where the balance between different species is crucial for overall health. Lactobacillus are bacteria, while Saccharomyces are yeasts; together, they offer a powerful, complementary approach to promoting gut health. This combination is particularly valued in supplements designed to restore balance after a microbial disruption, such as taking antibiotics.
Lactobacillus bacteria, including strains like L. rhamnosus, function by producing beneficial compounds such as lactic acid, which lowers the gut's pH and creates an environment unfavorable for harmful pathogens. They also help restore gut balance by outcompeting harmful bacteria. The probiotic yeast Saccharomyces boulardii, a non-pathogenic yeast, is known for its resilience and ability to survive the harsh stomach acid and bile, allowing it to reach and colonize the intestinal tract effectively. S. boulardii supports intestinal barrier function, neutralizes bacterial toxins, and has anti-inflammatory properties. When combined, their distinct yet complementary mechanisms provide a more robust defense against gastrointestinal disturbances.
Specific Supplements Containing Both Strains
While many probiotic products contain a wide array of strains, those specifically formulated with both Lactobacillus and Saccharomyces are particularly sought after for their synergistic effects. These products are often targeted toward managing specific conditions like antibiotic-associated diarrhea or IBS.
Here are some examples of supplements that incorporate both:
- Nexabiotic Multi Probiotic: This advanced formula includes multiple strains, with notable mentions of both Saccharomyces boulardii and various Lactobacillus species, such as L. acidophilus and L. rhamnosus. It features a delayed-release capsule to ensure the microbes reach the gut effectively.
- Lactobacillus+Saccharomyces Boulardii Combination Medications: Various pharmaceutical companies offer combination products, especially in sachet or capsule form. These are often prescribed for specific digestive issues under medical supervision.
- Bio-Live Gold: As a fruit-based probiotic liquid, this product contains a mixture of 13 strains, including Saccharomyces cerevisiae and several Lactobacillus species. This fermented liquid provides a unique, food-based delivery system for a diverse microbial community.
Fermented Foods with Lactobacillus and Yeasts
Besides supplements, certain fermented foods and beverages naturally contain both probiotic bacteria and yeasts, often living in a symbiotic relationship. These products are a great way to incorporate a diversity of microbes into your diet.
- Kefir: This fermented milk drink is made by adding kefir grains to milk, which are a complex symbiotic culture of bacteria and yeasts. The fermentation process results in a product rich in both Lactobacillus strains and various yeasts, including Saccharomyces cerevisiae.
- Kombucha: This popular fermented tea is made with a SCOBY (symbiotic culture of bacteria and yeast) and contains a mix of yeast species, such as Saccharomyces cerevisiae, along with various lactic acid bacteria. The final microbial composition can vary based on the fermentation process and ingredients.
- Traditional Buttermilk: While commercial buttermilk often lacks live cultures, traditional versions, which are the liquid left over from churning butter, naturally contain a mix of lactic acid bacteria and yeasts from the fermentation process.
Comparison of Common Probiotic Sources
| Source | Primary Type | Contains Both Strains? | Key Benefit | Considerations | 
|---|---|---|---|---|
| Kefir | Food/Beverage | Yes | Broad spectrum of both bacteria and yeasts | Microbial content can vary between batches | 
| Kombucha | Food/Beverage | Yes | Probiotic benefits from fermented tea | Sugar content can be high in commercial products | 
| Nexabiotic | Supplement | Yes | High concentration of specific, targeted strains | Must check label for specific strains and CFU count | 
| Plain Yogurt | Food/Beverage | Sometimes, depending on culture | Often contains Lactobacillus, but rarely yeast | Check for “live and active cultures” and low sugar | 
| Saccharomyces boulardii Capsules | Supplement | No (unless combined) | Highly effective for diarrhea, resistant to antibiotics | Must be combined with a separate Lactobacillus source for full synergy | 
Conclusion
The search for probiotics containing both Lactobacillus and Saccharomyces is driven by the desire for comprehensive gut health support. This powerful pairing, available in both targeted supplements and certain fermented foods, offers synergistic benefits for digestion, mucosal immunity, and microbial balance. While supplements like Nexabiotic and specific pharmaceutical combinations provide high concentrations of these specific strains, whole foods like kefir and kombucha offer a natural and diverse source. When selecting a product, it is important to consider the specific strains, concentration (CFU), and whether your health goals are best met by a targeted supplement or a whole-food approach. Always consult a healthcare provider, especially if you have a pre-existing condition or are immunocompromised.
What do probiotics have in them?
Probiotics are live bacteria and yeasts that have beneficial effects on your body. These species, such as Lactobacillus and Saccharomyces, are similar to the microorganisms that naturally live in your gut and other parts of your body. Probiotic products are designed to add to your existing supply of these friendly microbes to support your gut and immune health.
What are the best probiotics for women?
Many specific probiotic formulations are available for women's health, targeting issues like vaginal and urinary tract infections. Lactobacillus strains, particularly L. acidophilus, are often included in these products as they are naturally found in the vagina and urinary tract. A product like Nexabiotic, which contains a blend including L. acidophilus and Saccharomyces boulardii, is marketed toward both men and women for general gut health. However, effectiveness can be strain-specific, so it's best to consult a healthcare provider for recommendations based on individual needs.
What is a natural probiotic source?
Natural sources of probiotics include fermented foods like kefir, yogurt with live and active cultures, kombucha, sauerkraut, and kimchi. Kefir is a particularly good example of a food that naturally contains both Lactobacillus bacteria and various probiotic yeasts.
Can you take Lactobacillus and Saccharomyces at the same time?
Yes, it is common and often beneficial to take Lactobacillus and Saccharomyces (specifically S. boulardii) together. Their complementary actions mean they can work synergistically to support gut health. Since S. boulardii is a yeast and not affected by antibacterial treatments, it can be particularly useful to take alongside antibiotics to help restore gut flora.
Is Saccharomyces a bacterium?
No, Saccharomyces is a genus of yeast, which is a type of fungus. This distinguishes it from Lactobacillus, which is a genus of bacteria. The inclusion of both a beneficial yeast and beneficial bacteria in a probiotic product provides a more diverse and comprehensive approach to restoring gut balance.
Is Kefir a good source of probiotics?
Yes, kefir is an excellent natural source of probiotics, containing a diverse and potent mix of both lactic acid bacteria and yeasts, including Saccharomyces cerevisiae. The symbiotic culture of bacteria and yeast that forms the kefir grains provides a richer source of microbes than many other fermented products.
What is Lactobacillus commonly used for?
Lactobacillus species are commonly used to support digestive health, restore gut balance after antibiotic use, and manage various forms of diarrhea. Certain strains are also utilized for their potential benefits in supporting immune function and alleviating symptoms of lactose intolerance.
Citations
Uses of Lactobacillus + Saccharomyces Boulardii. Can the Evidence-Based Use of Probiotics (Notably ...) Sacchromyces boulardii Plus Lactobacillus reuteri. Efficacy and safety of the probiotic Saccharomyces boulardii. DrFormulas' Best Probiotics for Women & Men. Saccharomyces Boulardii - Uses, Side Effects, and More. Baby Probiotic oral: Uses, Side Effects, Interactions. Investigating Yeast–Lactobacilli Interactions through Co ... 11 Probiotic Foods That Are Super Healthy. Fermented nondairy functional foods based on probiotics. Fermented nondairy functional foods based on probiotics. Selection of appropriate probiotic yeasts for use in dairy products. The role of probiotics lactobacillus plantarum and saccharomyces boulardii. Probiotics - Health Professional Fact Sheet. Probiotics: What They Are, Benefits & Side Effects. Pathogen-Specific Benefits of Probiotic and Synbiotic Use. Lactobacillus+saccharomyces Boulardii: Uses, Side Effects and More.