Understanding the Fructan Family
Fructans are complex carbohydrates composed of chains of fructose molecules, often with a terminal glucose molecule. Because humans lack the enzymes to break them down in the small intestine, fructans travel mostly intact to the large intestine. Here, they serve as a food source for gut bacteria, undergoing fermentation. This fermentation process produces gas and can pull water into the bowel, which may cause symptoms like bloating, pain, and gas in sensitive individuals, particularly those with Irritable Bowel Syndrome (IBS).
The Two Main Types of Fructans: Inulin and FOS
The fructan family is broadly categorized into two main types based on their degree of polymerization (DP), which refers to the number of fructose units in the chain. Fructo-oligosaccharides (FOS) have a shorter chain length, while inulin is a longer-chain fructan.
- Fructo-oligosaccharides (FOS): These are short-chain fructans typically containing 2 to 9 fructose units. Due to their shorter chain length, FOS are generally fermented more rapidly by gut bacteria, often in the early part of the large intestine. Sources include onions, garlic, and bananas.
- Inulin: As longer-chain fructans with more than 10 fructose units, inulin is a larger molecule. Its longer, more complex structure means it is fermented more slowly and throughout the length of the large intestine. Inulin is found in foods like chicory root, artichokes, and wheat.
The Low-FODMAP Diet and Fructans
In the low-FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) diet, fructans fall under the 'O' for oligosaccharides. For individuals with a sensitivity, eliminating or reducing foods high in fructans, as well as other FODMAPs, can help manage symptoms. During the reintroduction phase of the diet, different fructan-containing foods might be tested individually to determine personal tolerance, as tolerance can vary widely.
Why the Distinction Matters for Digestive Health
Knowing the difference between FOS and inulin is helpful for managing gut symptoms. A person sensitive to fructans might react differently to sources high in FOS versus those high in inulin due to the varying fermentation rates along the colon. Digestive enzyme supplements containing fructan hydrolase are also available to help break down these carbohydrates before they reach the large intestine, potentially mitigating symptoms.
FOS vs. Fructans: A Comparison Table
| Feature | Fructans (Broad Category) | Fructooligosaccharides (FOS) | Inulin (Long-Chain Fructan) | 
|---|---|---|---|
| Classification | A family of carbohydrate polymers containing fructose units. | A subgroup of fructans with a short chain length. | A subgroup of fructans with a long chain length. | 
| Degree of Polymerization | Varies widely, from short-chain (FOS) to long-chain (inulin). | 2 to 9 fructose units. | 10 or more fructose units. | 
| Fermentation Speed | Varies; faster for shorter chains, slower for longer chains. | Fermented relatively quickly by gut bacteria. | Fermented more slowly over a longer period. | 
| Primary Fermentation Location | Primarily in the large intestine. | Mostly in the initial section of the large intestine. | Distributed throughout the large intestine due to slow fermentation. | 
| Dietary Sources | A wide variety, including wheat, garlic, onions, and asparagus. | Onions, garlic, leeks, and bananas. | Chicory root, artichokes, and wheat. | 
| Potential for Discomfort | High potential for symptoms in sensitive individuals, as with IBS. | Can cause rapid, intense gas and bloating in sensitive people due to fast fermentation. | May cause more sustained, but potentially less intense, symptoms due to slower fermentation. | 
The Prebiotic Role of FOS and Fructans
Both FOS and inulin are considered prebiotics, meaning they feed beneficial gut bacteria, particularly Bifidobacterium and Lactobacillus. This prebiotic effect is a major reason why they are added to many processed foods as a fiber booster. The type of prebiotic, however, can influence which bacteria it feeds and where in the colon this occurs. The fermentation of these fibers also produces short-chain fatty acids (SCFAs), which are important for colon health.
Fructans vs. Fructose: A Common Confusion
It is important not to confuse fructans with simple fructose. Fructose malabsorption is a condition where the small intestine has difficulty absorbing excess fructose molecules, typically found in fruits and honey. In contrast, fructans are chains of fructose that are not absorbed in the small intestine by anyone, regardless of whether they have fructose malabsorption or not. Symptoms can overlap, but the underlying mechanisms are different.
Conclusion
In summary, the statement that fructans are the same as FOS is inaccurate. FOS are a specific type of short-chain fructan, just as inulin represents the longer-chain variety. Both are members of the fructan family and function as prebiotics, feeding gut bacteria and contributing to digestive health. However, their different chain lengths result in different fermentation patterns in the gut, which can have varying effects on individuals, especially those with sensitivities. Understanding this nuance is key to navigating dietary choices and managing digestive comfort.
For more detailed information on fructans and their effects, the Monash University FODMAP website is an excellent authoritative resource on the subject.