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Are Twizzlers Anti-Inflammatory? The Surprising Truth

4 min read

According to research, high intake of added sugars can lead to chronic, low-grade inflammation throughout the body. So, are Twizzlers anti-inflammatory? Despite the licorice connection, the popular candy's ingredient profile points toward promoting, rather than reducing, inflammation.

Quick Summary

Understand why Twizzlers are considered a pro-inflammatory food and learn about the specific ingredients responsible. Examine the links between processed sugar and chronic health issues, and discover healthier snack alternatives.

Key Points

  • Not Anti-Inflammatory: Twizzlers are not anti-inflammatory; their primary ingredients, including sugar and corn syrup, contribute to inflammation.

  • Refined Sugars Promote Inflammation: High intake of processed and added sugars, like those in Twizzlers, leads to chronic low-grade inflammation via mechanisms such as AGE formation and cytokine release.

  • Licorice Confusion: The anti-inflammatory properties of true licorice root do not apply to the popular, sugar-laden Twizzlers candy, which often doesn't even contain licorice extract.

  • Causes of Chronic Inflammation: Excess sugar triggers insulin resistance and gut microbiome dysbiosis, both of which are major contributors to systemic inflammation.

  • Focus on Whole Foods: For an anti-inflammatory diet, choose whole foods like fruits, vegetables, nuts, and healthy fats instead of processed candies and sweets.

In This Article

The Ingredients That Define a Twizzler

To determine if Twizzlers are anti-inflammatory, it's crucial to examine their ingredient list. The primary components of popular Twizzlers flavors like strawberry are corn syrup, sugar, and enriched wheat flour. These are all refined carbohydrates and added sugars. Additionally, the candy contains artificial flavors and artificial colors, such as Red 40. A diet high in added sugar has been repeatedly linked to increased markers of chronic inflammation, such as C-reactive protein (CRP). Refined carbohydrates can cause rapid spikes in blood sugar levels, and foods with a high glycemic index (GI) are known to promote inflammation. Artificial additives are also components of ultra-processed foods, which have been associated with higher levels of inflammatory markers.

The Science Behind Sugar and Inflammation

Scientific studies have clearly established a link between excessive sugar intake and chronic low-grade inflammation. This long-term, systemic response can contribute to a host of health problems.

How Processed Sugar Contributes to Chronic Inflammation

  1. Advanced Glycation End Products (AGEs): High sugar intake accelerates the formation of AGEs, compounds that trigger oxidative stress and inflammation.
  2. Insulin Resistance: Constant high sugar intake can lead to insulin resistance, causing a cascade of inflammatory events.
  3. Gut Microbiome Dysbiosis: A high-sugar diet can disrupt the balance of gut bacteria, promoting pro-inflammatory bacteria and potentially increasing intestinal permeability.
  4. Cytokine Release: Excess sugar consumption can trigger inflammatory processes and the release of pro-inflammatory cytokines like interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α).

The Licorice Confusion: Twizzlers vs. Licorice Root

True black licorice root contains natural anti-inflammatory compounds. The licorice plant (Glycyrrhiza glabra) contains active components like glycyrrhizin with anti-inflammatory and antioxidant properties. However, this is different from modern candy. While original black licorice Twists contain licorice extract, popular strawberry versions do not. The amount of licorice extract in the candy is also unlikely to provide a therapeutic anti-inflammatory benefit due to the overwhelming quantity of added sugar and processed ingredients.

A Quick Comparison: Twizzlers vs. Anti-Inflammatory Foods

Feature Twizzlers Candy Anti-Inflammatory Foods Example
Primary Ingredients Corn syrup, sugar, enriched wheat flour, artificial flavors Whole foods like fruits, vegetables, nuts, seeds Blueberries, almonds, salmon
Nutrient Profile High in added sugar and refined carbs; virtually no nutritional value Rich in fiber, antioxidants, and healthy fats Berries, leafy greens, walnuts
Inflammatory Effect Pro-inflammatory due to high sugar and refined ingredients Anti-inflammatory due to antioxidants and phytonutrients Turmeric, ginger
GI (Glycemic Index) High, causing rapid blood sugar spikes Low, with slower, more stable blood sugar absorption Whole grains, legumes

Healthier Swaps: Anti-Inflammatory Alternatives to Candy

For sweet snacks aligned with an anti-inflammatory diet, consider alternatives that don't rely on processed sugar and refined flour.

  • Dark Chocolate (70%+ cocoa): Rich in antioxidants, offers anti-inflammatory benefits in moderation.
  • Cherries: Loaded with antioxidants and may help reduce inflammation.
  • Dried Fruit: Unsweetened dried fruit provides fiber and nutrients, but be mindful of portion size due to natural sugars.
  • Homemade Treats: Whole-food recipes using ingredients like nuts, dates, and coconut can offer healthier options.

Conclusion: Twizzlers and Your Health

Based on their ingredients, Twizzlers are not anti-inflammatory but are considered pro-inflammatory due to high added sugars and refined flour, especially in excess. The anti-inflammatory benefits of true licorice root do not apply to these candies. For those focused on reducing chronic inflammation, limit processed candies and choose whole-food alternatives rich in fiber and antioxidants. For additional information on anti-inflammatory eating, resources like the Harvard T.H. Chan School of Public Health provide guidance.

How to Reduce Inflammation in Your Diet

  • Prioritize Whole Foods: Focus on fruits, vegetables, and whole grains for fiber and antioxidants.
  • Limit Added Sugars: Be aware of hidden sugars in processed foods.
  • Increase Fiber Intake: Fiber helps regulate blood sugar and supports a healthy gut.
  • Incorporate Healthy Fats: Omega-3 fatty acids from sources like fish, nuts, and seeds have anti-inflammatory properties.
  • Stay Active: Regular exercise can reduce inflammatory markers.

The Role of Lifestyle Beyond Diet

  • Get Enough Sleep: Chronic lack of sleep is linked to chronic inflammation.
  • Manage Stress: High stress can increase inflammatory factors. Practice relaxation techniques.
  • Avoid Smoking: Smoking contributes to chronic inflammation.

The Anti-Inflammatory Potential of Licorice Root

  • Bioactive Compounds: Licorice root contains numerous compounds, with glycyrrhizin being a key active anti-inflammatory component.
  • Herbal vs. Candy: Research on licorice root's anti-inflammatory effects is based on the herbal supplement, not processed candy.
  • Therapeutic Dose: The amount of licorice extract in candy is negligible and unlikely to provide therapeutic benefits.

Understanding Different Types of Sugars

  • Natural vs. Added: Sugars in whole fruits, balanced by fiber and nutrients, are not linked to inflammation.
  • Fructose and Glucose: Excessive added sugars, particularly fructose and high-fructose corn syrup, are strongly linked to inflammation.
  • Refined Carbohydrates: Processed flour, like in Twizzlers, also causes blood sugar spikes.

Frequently Asked Questions

No, Twizzlers are not considered healthy. They are high in added sugars and refined carbohydrates and offer virtually no nutritional benefits, making them an occasional treat rather than a healthful snack.

While most processed candy is pro-inflammatory due to high sugar content, dark chocolate with 70% or more cocoa can have anti-inflammatory benefits from its high antioxidant content. However, moderation is key.

No. The Hershey Company states that only the original black licorice Twists contain licorice extract. The more popular fruit-flavored varieties, like strawberry, are considered "licorice type candy" and do not contain the extract.

Yes, high intake of sugar and other inflammatory foods has been shown to worsen joint pain by increasing inflammation in the body. Studies also suggest a link to conditions like rheumatoid arthritis.

Excessive intake of processed sugars leads to chronic, low-grade inflammation by triggering mechanisms such as insulin resistance, the release of inflammatory markers (cytokines), and disrupting the gut microbiome.

Healthier alternatives include snacks like fresh fruit (e.g., berries, cherries), nuts and seeds, or dark chocolate (70%+ cocoa). You can also find recipes for homemade, whole-food candies.

Fiber, found in whole foods like fruits, vegetables, and whole grains, is a powerful tool against inflammation. It feeds beneficial gut bacteria that help reduce inflammation throughout the body.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.