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Does soda affect the liver or kidneys? The surprising risks of sugar-sweetened and diet drinks

5 min read

According to a study published in the journal Clinical Gastroenterology and Hepatology, drinking just one sugary beverage daily for five to seven years could lead to fatty liver disease. This is just one piece of evidence indicating that excessive soda consumption, whether sugary or diet, can have serious consequences for both the liver and kidneys, contrary to popular belief that the risk is minimal.

Quick Summary

Chronic soda consumption poses a significant threat to liver and kidney health due to high sugar, artificial sweeteners, and phosphoric acid, potentially causing fatty liver disease, insulin resistance, kidney stone formation, and chronic kidney disease.

Key Points

  • Fructose Overload: The liver metabolizes fructose, and too much from sugary soda can lead to fatty liver disease (MASLD) by converting excess sugar into fat.

  • Diet Soda Risks: Despite being sugar-free, diet sodas may contribute to MASLD by affecting the gut microbiome, insulin resistance, and promoting inflammation.

  • Kidney Stone Risk: Phosphoric acid, common in dark colas, can increase the risk of kidney stones by creating an overly acidic environment in the urinary tract.

  • Chronic Kidney Disease: Regular consumption of both sugary and diet sodas is linked to a higher risk of developing chronic kidney disease.

  • Dehydration Issues: Caffeinated sodas act as a diuretic and can lead to dehydration, which is a major risk factor for kidney stones.

  • Healthy Alternatives: Water, flavored seltzer, herbal teas, and infused waters are excellent substitutes for soda to protect your liver and kidneys.

In This Article

The widespread consumption of soda, both regular and diet, has raised increasing concerns within the medical community regarding its long-term effects on vital organs. While it's common knowledge that these beverages are not healthy, the specific mechanisms by which they can harm the liver and kidneys are often misunderstood. A closer look at the ingredients reveals how regular and diet sodas can contribute to a range of chronic health issues.

The Damaging Effects of Soda on Liver Health

The Fructose Connection and Fatty Liver

The liver is the primary organ responsible for metabolizing fructose, a type of sugar found in high concentrations in sugar-sweetened beverages like regular soda. When you consume too much fructose, the liver becomes overwhelmed and converts this excess sugar into fat, a process known as de novo lipogenesis. This fatty buildup can lead to a condition called Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), formerly known as Non-Alcoholic Fatty Liver Disease (NAFLD).

Unlike glucose, fructose does not trigger insulin or leptin release, which are hormones that regulate appetite. This can result in a cycle of increased sugar consumption without feeling full, leading to further fat accumulation in the liver. Over time, MASLD can progress to more severe liver problems, including cirrhosis, a life-threatening condition involving liver scarring.

  • Key metabolic pathways affected by fructose:
    • De novo lipogenesis: The process of converting carbohydrates into fatty acids.
    • Insulin resistance: The body's cells become less responsive to insulin, a precursor to type 2 diabetes and MASLD.
    • Inflammation: The liver experiences inflammation, which is a key component in the progression of MASLD to more severe forms like MASH (metabolic dysfunction-associated steatohepatitis).

The Role of Artificial Sweeteners and Additives

Many assume diet sodas are a safer alternative, but research suggests they carry their own set of risks. Studies have linked heavy diet soda consumption to an increased risk of MASLD. The mechanism isn't fully understood, but hypotheses include:

  • Gut Microbiome Disruption: Artificial sweeteners may disrupt the balance of gut bacteria, which plays a role in metabolic health and can influence liver function.
  • Insulin Resistance: Despite having no sugar, artificial sweeteners can still influence insulin response and potentially lead to insulin resistance, a key risk factor for liver damage.
  • Chronic Inflammation: Certain additives and artificial sweeteners may promote chronic inflammation, contributing to liver issues.

How Soda Impacts Kidney Function

Phosphoric Acid and Kidney Stones

Dark-colored colas often contain high levels of phosphoric acid, an ingredient used for flavor and as a preservative. This acid can alter the urinary environment, making it more acidic and potentially promoting the formation of kidney stones. Kidney stones are mineral and salt deposits that can cause severe pain and complications as they pass through the urinary tract. The risk is particularly elevated in individuals who already have a history of kidney stones or other risk factors.

Dehydration and Chronic Kidney Disease

Chronic dehydration is a leading risk factor for kidney stone formation and can place a significant strain on the kidneys. Many sodas contain caffeine, a diuretic that increases urine production and can exacerbate dehydration, especially if individuals are not drinking enough water. The tendency for heavy soda drinkers to replace water with soda further compounds the problem. Furthermore, several studies have linked consistent, high consumption of both regular and diet soda to an increased risk of developing chronic kidney disease (CKD).

  • Factors contributing to kidney risk from soda:
    • High caffeine content: Acts as a diuretic, potentially causing dehydration.
    • Phosphoric acid: Creates an acidic urinary environment conducive to stone formation.
    • Associated health issues: Soda is linked to obesity and diabetes, which are major risk factors for chronic kidney disease.

Regular vs. Diet Soda: A Side-by-Side Comparison

Feature Regular Soda Diet Soda
Key Sweetener High Fructose Corn Syrup, Sucrose Artificial Sweeteners (e.g., aspartame)
Sugar Content High (e.g., ~37g in a 12oz can) Zero Sugar
Impact on Liver Excess fructose is converted to fat, leading to MASLD. May contribute to MASLD via gut microbiome disruption and inflammation.
Impact on Kidneys Risk of kidney stones via high fructose levels; increases risk of CKD via associated diabetes/obesity. Higher intake linked to accelerated kidney function decline and contains phosphoric acid in some versions.
Common Additive (Colas) Phosphoric acid, linked to increased risk of kidney disease and stones. Phosphoric acid, linked to increased risk of kidney disease and stones.

Protecting Your Liver and Kidneys: Healthier Alternatives

For those seeking to reduce soda consumption and protect their liver and kidneys, healthier hydration alternatives are readily available. These options provide flavor without the damaging sugar load, artificial additives, and acids found in soda.

  • Infused Water: Add slices of fresh fruit like lemon, lime, cucumber, or berries to plain water for a refreshing and naturally flavored drink.
  • Seltzer Water: Choose plain or naturally flavored seltzer water for a fizzy alternative without added sugars or phosphoric acid. Check labels carefully for artificial ingredients.
  • Herbal Tea: Brew iced herbal teas, such as peppermint, chamomile, or hibiscus, for a flavorful, caffeine-free beverage. Green tea is another healthy option, though some varieties contain caffeine.
  • Diluted Fruit Juice: Mix a small amount of 100% fruit juice with plain or sparkling water to cut the sugar content significantly.
  • Kombucha: This fermented tea contains probiotics that support gut health. Look for options with low added sugar.

Conclusion

While an occasional soda is unlikely to cause lasting harm, chronic, high consumption of both regular and diet varieties poses a clear risk to liver and kidney function. The high fructose content of sugary sodas contributes directly to fat accumulation in the liver and metabolic dysfunction. Meanwhile, ingredients like phosphoric acid and artificial sweeteners in both types of soda are associated with an increased risk of kidney disease and the formation of painful kidney stones. Ultimately, protecting these vital organs depends on making informed dietary choices. Reducing or eliminating soda and prioritizing healthier beverages like water is a fundamental step towards better long-term health. For those with underlying health conditions, speaking with a healthcare provider is essential for personalized advice and management. The American Kidney Fund provides more information and resources on kidney health.

Frequently Asked Questions

Excessive intake of fructose from sugary sodas can overwhelm the liver's ability to process it. The liver converts this surplus fructose into fat through a process called de novo lipogenesis, which leads to fat accumulation and nonalcoholic fatty liver disease (NAFLD/MASLD) over time.

Yes, some research suggests a link between heavy diet soda consumption and liver disease, particularly MASLD. Potential mechanisms include changes to the gut microbiome and increased insulin resistance caused by artificial sweeteners and additives.

Dark colas contain phosphoric acid, which can alter the urine's chemistry and increase the likelihood of kidney stone formation from mineral deposits. Additionally, the caffeine in many sodas contributes to dehydration, another major risk factor for stones.

Not necessarily. While some studies show diet soda may pose a smaller risk for kidney stones than regular soda, heavy consumption of diet soda has been independently linked to accelerated kidney function decline in some populations. Both should be consumed in moderation.

Studies have shown risks associated with consuming as little as one or two sugary or carbonated beverages daily. The risk increases with higher frequency and quantity, so medical experts recommend limiting intake or avoiding it altogether.

Early symptoms of liver problems can be subtle and include nausea, a loss of appetite, and fatigue. In more advanced stages of fatty liver disease, symptoms can include pain in the upper right abdomen and jaundice (yellowing of the skin and eyes).

The best alternative is always plain water, but other excellent choices include herbal teas, sparkling water with a splash of natural fruit juice, or infused water with fresh fruits and vegetables.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.