Is it healthy to eat mangosteen? Exploring the Queen of Fruits' Benefits and Risks

November 17, 2025 •

4 min read

According to a 2015 study published by the National Institutes of Health, a mangosteen-based formula significantly increased antioxidant capacity in human blood. So, is it healthy to eat mangosteen? The answer is a resounding yes, as long as it's consumed in moderation.

Quick Summary

This guide examines the nutritional profile of mangosteen, its health benefits including antioxidant and anti-inflammatory properties, potential side effects, and safe consumption guidelines.

Key Points

Rich in Xanthones: Mangosteen is packed with unique and potent antioxidants called xanthones, especially in its rind.
Reduces Inflammation: Its compounds have been shown to reduce markers of inflammation in the body.
Supports Skin Health: The fruit's antioxidants protect the skin from free radicals and UV damage, promoting elasticity and a youthful appearance.
Aids Digestion: As a good source of fiber, mangosteen helps promote digestive health and prevent constipation.
Potential Blood Sugar Control: Research suggests that mangosteen compounds may help regulate blood sugar levels and improve insulin sensitivity.
Avoid Concentrated Forms with Caution: Individuals on blood thinners or with bleeding disorders should be cautious with concentrated extracts due to potential blood-clotting interference.
Moderate Intake Recommended: For most people, a moderate intake of fresh mangosteen is safe and beneficial, while excessive consumption may lead to digestive issues.

Exploring the Nutritional Profile of Mangosteen

Often called the "queen of fruits," mangosteen is not only delicious but also packed with a unique set of nutrients. A single 196-gram cup of canned, drained mangosteen provides approximately 143 calories, 1 gram of protein, 1 gram of fat, and 35 grams of carbohydrates, including a good amount of fiber. This fruit is also a valuable source of vitamins and minerals essential for various bodily functions, from wound healing to immunity.

Key Nutrients in Mangosteen (per 196-gram cup):

Vitamins: A good source of vitamin C, which is crucial for a healthy immune system, and folate (vitamin B9), vital for DNA production and cell growth.
Minerals: Contains essential minerals like manganese, copper, and magnesium, which play roles in metabolic processes and nerve signaling.
Fiber: A cup provides about 3.5 grams of fiber, which is important for digestive health and promoting a feeling of fullness.
Xanthones: A unique class of powerful antioxidants found in mangosteen, particularly concentrated in the inedible purple rind. These compounds are linked to many of the fruit's potential health benefits.

The Scientifically Supported Health Benefits of Mangosteen

Beyond its impressive nutrient content, mangosteen's true power lies in its unique plant compounds, which have been studied for their wide-ranging therapeutic effects.

Rich in Antioxidants

The most notable component of mangosteen is its high concentration of xanthones, a type of plant compound with potent antioxidant capabilities. Antioxidants help neutralize free radicals, which are unstable molecules that can cause cellular damage and contribute to chronic diseases. Studies have shown that consuming a mangosteen-rich beverage can significantly increase the body's antioxidant capacity.

Anti-inflammatory Effects

Inflammation is a natural bodily response, but chronic low-grade inflammation is linked to serious health conditions like heart disease, cancer, and diabetes. The xanthones and fiber in mangosteen have been observed to possess anti-inflammatory properties. Research has indicated that mangosteen consumption may lead to a significant decrease in C-reactive protein (CRP) levels, a key marker of inflammation.

Supports Blood Sugar Control

Mangosteen may offer benefits for blood sugar management due to its fiber content and specific compounds. The fruit's fiber helps stabilize blood sugar by slowing carbohydrate absorption. In addition, test-tube and animal studies have suggested that xanthones may help maintain healthy blood sugar levels and improve insulin sensitivity.

Promotes Healthy Skin

The antioxidant and anti-inflammatory properties of mangosteen may also translate to skin health benefits. Research has shown protective effects against damage from ultraviolet-B (UVB) radiation in mice and improved skin elasticity in human studies. This suggests the fruit can help combat oxidative stress and inflammation, two major contributors to premature skin aging.

Potential Risks and Considerations

While fresh mangosteen is generally safe for most people when consumed in moderation, there are a few important considerations, particularly for concentrated forms.

Drug Interactions and Bleeding Risk

Concentrated mangosteen products, like supplements or juices, contain high levels of xanthones that may slow blood clotting. Individuals with bleeding disorders or those taking blood-thinning medications should avoid these concentrated forms. It is also recommended to stop taking mangosteen supplements at least two weeks before surgery.

Gastrointestinal Issues

Excessive intake of mangosteen, particularly in supplement form, can cause gastrointestinal side effects such as constipation, bloating, and nausea. Moderation is key to avoiding digestive discomfort.

Insufficient Data for Pregnancy and Breastfeeding

There is a lack of reliable information regarding the safety of mangosteen supplements during pregnancy and breastfeeding. To err on the side of caution, these populations should avoid concentrated forms and consult a healthcare provider.

Mangosteen vs. Other Popular Fruits: A Nutritional Comparison

Comparing mangosteen to other popular fruits can help put its nutritional value in perspective. While its nutritional metrics may not outshine all fruits, its unique benefits are noteworthy.


Feature	Mangosteen (per 100g)	Banana (per 100g)	Avocado (per 100g)
Calories	73	89	160
Carbohydrates	18g	22.8g	8.5g
Fiber	1.8g	2.6g	6.7g
Vitamin C	2.9mg	8.7mg	10mg
Potassium	48mg	358mg	485mg
Key Antioxidants	Xanthones	Flavonoids	Polyphenols

This comparison shows that mangosteen holds its own nutritionally, especially regarding its low-calorie profile. However, other common fruits may provide more fiber or specific vitamins and minerals, highlighting the importance of a varied diet. The presence of xanthones is what makes mangosteen truly unique.

Conclusion: A Healthy Addition to a Balanced Diet

So, is it healthy to eat mangosteen? Yes, incorporating fresh mangosteen into a balanced diet can be a healthy choice due to its rich antioxidant and anti-inflammatory properties, largely attributed to its unique xanthone compounds. It also provides essential vitamins, minerals, and fiber that support overall health, including skin vitality, immune function, and digestion.

However, it is crucial to consume mangosteen in moderation and be aware of the potential risks associated with high doses of concentrated extracts or supplements, such as blood-clotting issues and gastrointestinal upset. It is always best to consult a healthcare professional before adding any new supplement to your regimen, especially if you have pre-existing conditions or are pregnant. For more scientific insights into the health benefits of mangosteen, explore the research conducted by the National Institutes of Health.

Ultimately, enjoying fresh mangosteen is a delicious way to boost your nutrient intake and reap the benefits of this tropical delicacy.

Frequently Asked Questions

Despite their similar names, mangosteen and mango are two completely different tropical fruits with no relation to each other. Mangosteen has a thick purple rind and white, sweet-tart flesh, while a mango has a thinner skin and sweet, fibrous yellow or orange flesh.

The edible part of the mangosteen is the soft, white, juicy segmented flesh found inside the thick, inedible purple rind. The rind is traditionally used for medicinal extracts but should not be eaten directly.

Yes, it is generally considered safe for most healthy individuals to eat mangosteen every day in moderation. Consuming 1 to 3 fresh mangosteens per day is a common recommendation to gain benefits without excessive sugar or fiber intake.

While fresh mangosteen has minimal side effects, concentrated supplements may cause constipation, bloating, nausea, or slow blood clotting, especially in high doses. It is important to consume supplements with caution and consult a doctor.

Mangosteen may assist with weight management due to its high fiber content and low-calorie count, which can help increase feelings of fullness. Its anti-inflammatory properties may also play a role in promoting fat metabolism. However, it should be part of a balanced diet and active lifestyle.

Mangosteen contains fiber and xanthone compounds that can help regulate blood sugar levels by slowing carbohydrate absorption and potentially improving insulin sensitivity. However, individuals with diabetes should monitor their intake and consult a doctor before consuming large amounts.

Xanthones are a class of powerful antioxidant compounds found in mangosteen, particularly concentrated in the rind. They are responsible for many of the fruit's potential health benefits, including its anti-inflammatory, anticancer, and antidiabetic effects.