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Is Licorice Root Good for the Esophagus? Benefits and Safety

4 min read

In a 2017 study, a licorice root-based herbal formula showed better results for reducing GERD symptoms over two years compared to standard antacids. This highlights the potential for licorice root, particularly in its modified form.

Quick Summary

Licorice root, especially deglycyrrhizinated licorice (DGL), may improve esophageal health by boosting protection, reducing inflammation, and relieving acid reflux symptoms. Safety is key, especially with standard licorice, due to the compound glycyrrhizin, which may cause adverse effects.

Key Points

  • DGL is the Preferred Form: Opt for deglycyrrhizinated (DGL) licorice for esophageal benefits without the risks of standard licorice.

  • Increases Mucosal Protection: DGL stimulates mucus production, forming a protective barrier that shields the esophageal lining.

  • Reduces Inflammation: The flavonoids in DGL offer anti-inflammatory and soothing properties, calming esophageal irritation.

  • Supports Gastric Health: Licorice root may balance stomach acidity, supporting overall digestive health.

  • Requires Professional Advice: It's vital to consult a healthcare provider before using DGL, particularly for chronic issues, to discuss dosage and medication interactions.

  • Best Before Meals: Take chewable DGL tablets 15-20 minutes before eating for optimal effects.

In This Article

Licorice Root and Esophageal Health: A Deep Dive

Licorice root, sourced from the Glycyrrhiza glabra plant, has been used in traditional medicine for many centuries to treat various ailments, particularly concerning the digestive system. A key area of interest is the esophagus, which is frequently irritated and damaged by acid reflux, a symptom of gastroesophageal reflux disease (GERD). The possible advantages of licorice root are from its protective and anti-inflammatory properties; however, the specific form used is important.

How Licorice Root Supports Esophageal Health

Licorice root contains compounds that provide a multi-faceted approach to supporting esophageal health by addressing the underlying causes of acid reflux and irritation.

  • Enhanced Mucosal Protection: Licorice helps increase the production of mucin, a protective substance that coats the lining of the digestive tract. This layer acts as a barrier, protecting the delicate esophageal tissue from the corrosive effects of stomach acid.
  • Anti-Inflammatory Action: The active compounds, particularly the flavonoids found in deglycyrrhizinated licorice (DGL), have anti-inflammatory properties that can help soothe irritation and support tissue repair in an inflamed esophagus.
  • Stomach Acid Regulation: There's evidence to suggest that licorice can help modulate stomach acid production, balancing acidity levels and lessening the chance of reflux episodes.

Deglycyrrhizinated Licorice (DGL): The Preferred Choice

While the whole licorice root offers useful compounds, it also includes glycyrrhizin. Though powerful, this substance can cause significant adverse effects, including elevated blood pressure, fluid retention, and low potassium levels, particularly with chronic or high-dose consumption. For this reason, the deglycyrrhizinated (DGL) form is the better and safer choice for managing esophageal issues. DGL has the glycyrrhizin removed, retaining the healing properties without the hypertensive side effects.

  • DGL: Processed to eliminate glycyrrhizin, making it safer for long-term use.
  • Whole Licorice Root: Contains glycyrrhizin, with risks that include high blood pressure and low potassium.

Risks, Side Effects, and Precautions

Despite DGL generally being safe, it's essential to be aware of the risks connected to any herbal supplement. The FDA does not regulate herbal supplements, so potency and quality can vary among brands.

  • Interactions: Licorice, particularly the non-DGL form, can interact with medications for blood pressure, diuretics, and corticosteroids.
  • Pregnancy: Pregnant women should avoid licorice supplements, as they may increase the risk of preterm labor.
  • Digestive Discomfort: Some individuals might experience mild digestive upset, especially when first starting a DGL regimen.

Using DGL for Esophageal Support

DGL supplements are widely available in various forms, with chewable tablets being a popular option for targeted esophageal relief. Chewing the tablets promotes saliva production, which enhances the coating effect on the esophagus.

Common DGL Forms:

  • Chewable Tablets: Chewable DGL is recommended to mix with saliva for optimal effectiveness, coating the esophagus before reaching the stomach.
  • Capsules: A non-chewable option, often taken with water before meals.
  • Powder: Can be mixed into water or other beverages.

Licorice Root vs. Traditional Antacids: A Comparison

For those seeking an alternative to conventional medications, a comparison of DGL with standard antacids is helpful. Traditional antacids, H2 blockers, and proton pump inhibitors (PPIs) work by neutralizing or reducing stomach acid. In contrast, DGL strengthens the body's own defense mechanisms.

Feature DGL (Deglycyrrhizinated Licorice) Standard Antacids (e.g., Tums, Gaviscon)
Mechanism Enhances mucosal protective barrier; reduces inflammation. Neutralizes excess stomach acid; provides temporary relief.
Best For Long-term support, healing, and prevention of reflux damage. Immediate, temporary relief of occasional heartburn.
Side Effects Minimal in DGL form; high doses of regular licorice can cause high blood pressure. Potential side effects like constipation or diarrhea; not for long-term use.
Effectiveness Studies show comparable efficacy to antacids in mild cases; promotes healing. Effective for rapid relief, but doesn't address the underlying damage.

Conclusion: The Role of DGL in Esophageal Health

Licorice root, especially in its DGL form, is a promising natural remedy to support the esophagus. Its ability to promote mucosal healing and lessen inflammation makes it a viable option for those with acid reflux and GERD, especially for long-term management. While not a cure-all, and severe conditions need a doctor's supervision, DGL provides a well-tolerated alternative to conventional acid-suppressing drugs. As with any new supplement, consulting a healthcare provider is recommended to ensure it's appropriate for individual needs. For more insights into natural digestion remedies, consider exploring reputable health resources, such as the National Center for Complementary and Integrative Health.

Lifestyle Changes for Better Esophageal Health

  • Embrace an Anti-Inflammatory Diet: Include fiber-rich foods and limit trigger foods like spicy, fatty, or acidic items.
  • Avoid Lying Down After Meals: Wait at least 2-3 hours after eating before lying down to prevent reflux.
  • Elevate Your Head While Sleeping: Use a wedge pillow to keep your head and chest elevated during sleep.
  • Manage Stress: Stress can exacerbate GERD symptoms; stress management techniques may help.
  • Maintain a Healthy Weight: Excess weight can put pressure on the stomach, worsening reflux.

Final Thoughts

In summary, licorice root, particularly the deglycyrrhizinated (DGL) form, can be beneficial for the esophagus by protecting the mucosal lining, reducing inflammation, and alleviating acid reflux symptoms. It provides a supportive, natural alternative to some conventional treatments, working with the body’s own healing mechanisms. It is essential to choose DGL over whole licorice root to avoid potential side effects like high blood pressure. Incorporating DGL with other lifestyle modifications, such as dietary changes and stress management, offers a complete approach to managing esophageal health. For more information on natural remedies for various health conditions, explore the resources available at the National Center for Complementary and Integrative Health.

Frequently Asked Questions

Regular licorice root has glycyrrhizin, which may cause high blood pressure. DGL, or deglycyrrhizinated licorice, has this compound removed, offering digestive benefits without side effects.

DGL supports mucin production, which protects the mucosal lining of the esophagus from irritating stomach acid. This allows damaged tissue to heal and prevents more irritation.

Yes, especially the DGL form. DGL has been shown to reduce GERD and acid reflux symptoms by supporting mucosal healing and offering an anti-inflammatory effect.

DGL is generally safe for long-term use because the glycyrrhizin compound has been removed. Some might experience mild digestive upset initially.

For best results, chewable DGL tablets should be chewed 15-20 minutes before meals. Chewing mixes the supplement with saliva, which helps activate its protective compounds.

DGL and antacids work differently. Antacids neutralize stomach acid for temporary relief, while DGL supports the body's natural defenses. Some studies suggest DGL can be more effective for chronic symptoms.

Those with high blood pressure or heart or kidney problems should avoid glycyrrhizin-containing licorice root. Pregnant women should avoid all licorice supplements. Anyone on medication should consult a doctor because of potential interactions.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.