The Troubling Case of Red Dye No. 3
After decades of regulatory inaction, the FDA finally revoked authorization for Red Dye No. 3 (Erythrosine) in food and ingested drugs, effective January 2025. This decision follows evidence from the 1980s showing the dye caused thyroid cancer in male laboratory rats. Although the dye was banned in cosmetics and external drugs in 1990 based on these findings, its use in food persisted for over 30 years despite the federal Delaney Clause, which prohibits additives found to cause cancer.
The ban on Red 3 is a response to renewed petitions and public pressure. Manufacturers have until January 2027 to remove it from food and January 2028 for ingested drugs. The FDA noted the specific cancer mechanism found in rats might not apply to humans, but the legal requirement of the Delaney Clause necessitated the ban. Red 3, which offers no nutritional value, was commonly found in items like certain candies, maraschino cherries, fruit cocktails, and some children's medications. Until the ban is fully implemented, consumers should check ingredient labels to avoid this dye.
The Controversy Around Red Dye No. 40 and Other Dyes
Beyond the banned Red Dye No. 3, Red Dye No. 40 (Allura Red AC) is another widely used artificial coloring facing scrutiny. Derived from petroleum, Red 40 is primarily linked to behavioral issues in sensitive children, such as hyperactivity and inattentiveness. A 2021 report from California's OEHHA supported the link between synthetic food dyes and neurobehavioral problems.
Studies indicate that food dyes may worsen existing symptoms in some children, rather than directly cause conditions like ADHD. Consequently, the European Union has mandated warning labels on foods with certain dyes, including Red 40, since 2010, leading many European companies to use natural alternatives. Other dyes, such as Yellow Dye No. 5 (Tartrazine) and Yellow Dye No. 6, are also associated with hyperactivity and potential allergic reactions. Animal studies have suggested other risks for Red 40, including potential DNA damage, but human implications require further research.
Artificial vs. Natural Dyes: A Comparison
Making informed dietary choices requires understanding the differences between artificial and natural food colorings. Below is a table highlighting these distinctions.
| Feature | Artificial Dyes (e.g., Red 3, Red 40) | Natural Dyes (e.g., Beetroot, Turmeric) | 
|---|---|---|
| Source | Petroleum or coal tar | Plants, fruits, vegetables, and other natural sources | 
| Processing | Synthetic and manufactured via chemical processes | Extracted from natural sources with minimal processing | 
| Intensity/Stability | Produce very bright, consistent, and stable colors | Colors can vary in hue and may be less stable or more sensitive to heat | 
| Health Concerns | Linked to cancer (Red 3) and neurobehavioral issues (Red 40) | Generally considered safe, with some offering additional health benefits | 
| Nutritional Value | None; purely cosmetic | Some, like those from turmeric or berries, may offer antioxidants | 
| Common Use | Processed candies, sugary cereals, snacks, and brightly colored drinks | Healthier products, organic foods, and naturally-colored items | 
Practical Nutrition Diet Tips for Avoiding Artificial Dyes
Avoiding artificial food dyes in your diet involves being mindful of food choices and labels. Here are some practical tips:
- Read ingredient lists diligently. Artificial dyes are listed by their full name or number (e.g., FD&C Red No. 3, Red 40).
 - Emphasize whole, unprocessed foods. Focusing on fruits, vegetables, whole grains, nuts, and seeds naturally reduces exposure to artificial dyes.
 - Use natural colorings for homemade foods. Ingredients like beet juice or turmeric can provide natural colors for cooking and baking.
 - Seek products with natural alternatives. Look for packaged goods that use natural colorings from sources like beet juice, paprika, or annatto.
 - Choose 'dye-free' options when available. Some medications, particularly for children, offer dye-free versions.
 
How to Read a Food Label for Dyes
When examining food labels, specifically look for the following to identify potentially problematic dyes:
- FD&C Red No. 3 or Erythrosine: The dye banned due to cancer links.
 - FD&C Red No. 40, Allura Red AC, or Red 40 Lake: The dye associated with hyperactivity.
 - FD&C Yellow No. 5 or Tartrazine: Linked to hyperactivity and allergies.
 - FD&C Yellow No. 6 or Sunset Yellow: Also linked to hyperactivity.
 
Conclusion
Understanding what number red dye is not good for you highlights the complex history and ongoing concerns surrounding certain food additives. The recent FDA ban on Red Dye No. 3 acknowledges its cancer risks and underscores the importance of consumer awareness. Concerns also persist regarding Red Dye No. 40 and other synthetic colorings due to their potential link to behavioral issues, especially in children. By prioritizing whole, unprocessed foods and opting for natural color alternatives, individuals can minimize their exposure to these potentially harmful dyes and support a healthier diet. This shift toward natural ingredients is a move towards a cleaner, more nutritious way of eating.