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Understanding Low-Calorie Sweeteners: What Sweetener is 2000 Times Sweeter Than Sugar?

5 min read

According to the U.S. Food and Drug Administration (FDA), several high-intensity sweeteners exist, with some being thousands of times sweeter than sucrose. This remarkable potency means that only minute quantities are needed to achieve a sweet taste, drastically reducing or eliminating caloric impact for those on a specific nutrition diet. When asking what sweetener is 2000 times sweeter than sugar, the answer points to a few candidates, including both artificial and natural options.

Quick Summary

Alitame and Thaumatin are two intense sweeteners that are approximately 2000 times sweeter than sugar. Alitame is an artificial dipeptide sweetener with limited regulatory approval, while Thaumatin is a natural protein derived from the katemfe fruit and also serves as a flavor enhancer.

Key Points

  • Alitame is an artificial dipeptide sweetener: Developed by Pfizer, it is approximately 2000 times sweeter than sugar and is safe for individuals with phenylketonuria (PKU).

  • Thaumatin is a natural protein sweetener: Extracted from the West African katemfe fruit, its sweetness ranges from 2000 to 3000 times that of sugar and it also functions as a flavor enhancer.

  • Regulatory status varies by region: Alitame is not approved for use in the US or EU, while Thaumatin is approved as a flavor enhancer in the US and as a sweetener in the EU, Japan, and Australia.

  • Taste profiles are distinct: Alitame is known for a clean taste, whereas thaumatin has a slow onset and a lingering aftertaste, sometimes described as licorice-like.

  • Intense sweeteners support dietary goals: Both can be used in low-calorie and sugar-free products to help manage weight, control blood sugar, and reduce caloric intake.

  • Safety is based on testing: Approved sweeteners undergo extensive review by authorities like the FDA and JECFA, with specific ADIs established based on safety studies.

  • Long-term effects are still under study: Some health organizations recommend caution, especially for children, due to limited data on the long-term impact of non-nutritive sweetener consumption.

In This Article

The World of Intense Sweeteners

The quest for sugar alternatives has led to the development and discovery of a wide array of intense sweeteners. These compounds, both synthetic and derived from nature, offer significant sweetness without the caloric burden of sugar (sucrose). Their intense potency allows for their use in minuscule amounts, making them viable for low-calorie and sugar-free products. For those seeking a nutritional diet, intense sweeteners can be a powerful tool for managing weight or regulating blood sugar. The category includes well-known names like aspartame and sucralose, but also less common, yet exceptionally potent, options.

Two primary contenders fit the description of being approximately 2000 times sweeter than sugar: the artificial sweetener alitame and the natural protein thaumatin. While both are significantly sweeter than sucrose, they differ dramatically in their origin, taste profile, and regulatory status, which impacts their applications in food and beverages.

Alitame: The Artificial Dipeptide Sweetener

Alitame, a dipeptide sweetener developed by Pfizer in 1979, is approximately 2000 times sweeter than sucrose. It is synthesized from the amino acids L-aspartic acid and D-alanine. A key advantage of alitame is that, unlike its precursor aspartame, it does not contain phenylalanine, making it a safe sugar substitute for individuals with phenylketonuria (PKU).

  • Stability: Alitame exhibits superior stability under a variety of conditions, including heat and a broad pH range (5-8), making it suitable for a wider range of food processing and baking applications than aspartame.
  • Taste Profile: It is known for a clean, sucrose-like taste without the bitter or metallic aftertaste often associated with other high-intensity sweeteners. However, some reports note it can have a mild bitter side-taste.
  • Regulatory Status: Alitame's primary limitation is its regulatory approval. It has been approved for use in countries like Mexico, China, Australia, and New Zealand but not in the United States or the European Union. The petition for its use in the US was withdrawn by its manufacturer, indicating limited commercial interest or challenges in the approval process.

Thaumatin: The Natural Protein Sweetener

Thaumatin is an intensely sweet-tasting protein extracted from the katemfe fruit (Thaumatococcus daniellii), a plant native to West Africa. Its sweetness is typically cited as being between 2000 and 3000 times sweeter than sucrose, putting it squarely in the target range.

  • Taste Profile: Unlike the immediate sweetness of sugar, thaumatin's sweetness has a slow onset and a lingering, sometimes licorice-like, aftertaste, which can limit its use as a standalone sweetener. This unique profile, however, makes it valuable as a flavor enhancer at subsweetening levels.
  • Functionality: In addition to its sweetening properties, thaumatin can mask bitter and metallic off-flavors, which is particularly useful in low-sodium products or to improve the taste of other sweeteners.
  • Metabolism and Safety: As a protein, thaumatin is metabolized into its constituent amino acids, providing a negligible amount of calories due to its intense sweetness. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has given thaumatin an Acceptable Daily Intake (ADI) of “not specified,” indicating no safety concerns at typical usage levels.
  • Regulatory Status: Thaumatin is approved as a sweetener in the European Union (E957), Japan, and Australia, among other countries. In the United States, it is generally recognized as safe (GRAS) for use as a flavor enhancer but not specifically as a sweetener.

A Comparison of Sweeteners

Feature Alitame (Artificial) Thaumatin (Natural) Sucrose (Sugar)
Origin Dipeptide from amino acids Protein from katemfe fruit Sugarcane or sugar beets
Sweetness (vs Sucrose) ~2000x 2000–3000x 1x
Calories Virtually zero Virtually zero ~4 kcal/gram
Taste Profile Clean, sucrose-like, some report mild aftertaste Slow onset, lingering sweetness, possible licorice aftertaste Standard, immediate sweetness
Regulatory Status (USA) Not approved GRAS as a flavor enhancer N/A (Standard food)
Use Cases Heat-stable products (if approved), tabletop sweeteners Flavor modification, masking bitter flavors, combined with other sweeteners All food and drink applications

Implications for a Nutrition Diet

The integration of intense sweeteners into a diet can have significant implications for managing calorie intake and addressing specific health needs. For example, replacing caloric sugar with a zero-calorie sweetener can aid in weight loss and help manage blood sugar levels for individuals with diabetes. However, the choice of sweetener is not always straightforward and depends on desired applications and taste preferences.

Pros of Intense Sweeteners in a Diet:

  • Calorie Reduction: The primary benefit is a massive reduction in caloric intake, which can support weight management goals.
  • Blood Sugar Control: Since they do not impact blood sugar levels, intense sweeteners are suitable for diabetics and those seeking to control glucose spikes.
  • Dental Health: Unlike sugar, they are not cariogenic and do not promote tooth decay.
  • Flavor Enhancement: Certain sweeteners like thaumatin can enhance the natural flavors of other ingredients and mask unpleasant tastes.

Cons and Considerations:

  • Taste Profile: The specific taste profiles, including aftertastes, differ significantly from sugar, which can be an adjustment for some palates.
  • Regulatory Limits: The approval status of different sweeteners varies by region, limiting options depending on location.
  • Long-Term Effects: While approved sweeteners have undergone extensive safety testing, concerns about the long-term metabolic and gut health effects of some synthetic varieties still exist. The American Academy of Pediatrics recommends that children avoid non-nutritive sweeteners due to lack of long-term data.

Conclusion

When considering what sweetener is 2000 times sweeter than sugar, both alitame and thaumatin are valid answers, though their practical use varies greatly. Thaumatin, a natural protein from West African fruit, is the more widely accepted and used in the food industry, especially for its flavor-enhancing properties. Alitame, a synthetic dipeptide, offers excellent stability and a clean taste but is not approved in major markets like the US and EU. For consumers, the choice between these and other intense sweeteners depends on their dietary goals, taste preferences, and regulatory landscape. Always prioritize sweeteners approved by relevant health authorities and consider a balanced approach to your nutrition plan.

The Role of Intense Sweeteners in Sugar Reduction

  • Dietary Strategy: Many individuals on a nutrition diet leverage intense sweeteners to reduce sugar intake without sacrificing sweet flavors, enabling them to adhere to health goals more consistently.
  • Product Development: Food scientists use combinations of sweeteners to achieve a taste profile closer to sugar and address specific texture or stability needs.
  • Managing Cravings: For those trying to reduce sugar dependence, high-intensity sweeteners can provide a satisfying sweet flavor without triggering the same glycemic response or caloric intake.

For more detailed information on specific sweeteners and food additive regulations, consult official sources like the U.S. Food & Drug Administration or regional food safety authorities. A good starting point can be found on the FDA's website regarding sweeteners: https://www.fda.gov/food/food-additives-petitions/aspartame-and-other-sweeteners-food.

Frequently Asked Questions

The main differences are their origin and regulatory status. Alitame is an artificial dipeptide sweetener not approved in the US, while Thaumatin is a natural protein from the katemfe fruit and is generally recognized as safe (GRAS) in the US as a flavor enhancer.

Thaumatin has a strong safety profile and has been assigned an 'ADI not specified' by JECFA. Alitame has been approved in several countries, but due to its lack of approval in the US and EU, it is not widely used.

Yes, thaumatin is known for its ability to function as a flavor enhancer, even at concentrations below its sweetness threshold. It is often used to mask undesirable flavors, like bitterness or metallic tastes.

Yes, unlike aspartame, alitame does not contain phenylalanine, making it safe for individuals with phenylketonuria (PKU).

As non-caloric, intense sweeteners, neither alitame nor thaumatin significantly impacts blood sugar levels, making them suitable for diabetics and those managing blood glucose.

The regulatory process for food additives is complex and can be expensive. The manufacturer withdrew the petition for alitame's approval in the US, potentially due to commercial considerations, though no specific safety concerns have been widely publicized.

Thaumatin is used in many foods and beverages, often as a flavor enhancer. You can find it in chewing gum, beverages, dairy products, and certain baked goods, typically listed as 'thaumatin' or under its E number (E957 in Europe).

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.