The Connection Between Diet and Inflammation
Ankylosing spondylitis (AS) is a chronic, inflammatory autoimmune disease that primarily affects the spine and sacroiliac joints. The hallmark of AS is inflammation, and diet is a significant factor known to influence inflammation levels throughout the body. While a specific, universal AS diet does not exist, many patients find relief by adopting an anti-inflammatory eating pattern and avoiding particular foods they identify as triggers. These food triggers can exacerbate the autoimmune response and contribute to painful flare-ups.
Sugary and Processed Foods
Excessive intake of added sugars and refined carbohydrates is consistently linked to increased inflammation. These foods can cause a spike in blood sugar, which triggers the release of inflammatory messengers. This category includes more than just candy and desserts; it also encompasses many processed foods and sugary beverages.
- Foods to limit or avoid:
- Sodas, juices with added sugar, and energy drinks.
- Baked goods, pastries, and candy.
- Refined grains, such as white bread, white rice, and crackers.
- Packaged snacks and pre-made sauces that contain added sugars.
 
Unhealthy Fats
Not all fats are created equal. While healthy fats like omega-3 fatty acids are anti-inflammatory, saturated fats and trans fats promote inflammation.
- Saturated Fats: Found in high concentrations in red meat and full-fat dairy products, these fats can aggravate inflammation.
- Trans Fats: Often listed as "partially hydrogenated oils" on food labels, trans fats should be avoided altogether due to their strong link to inflammation and heart disease. They are commonly found in fried foods, fast food, and certain baked goods.
- Omega-6 Fatty Acids: While essential in moderation, many Western diets contain an excess of omega-6 fatty acids compared to omega-3s, which can lead to a pro-inflammatory state. Common sources include corn, soy, and sunflower oils, as well as mayonnaise and salad dressings.
Red and Processed Meats
Red meat, including beef, lamb, and pork, contains compounds like saturated fat and an inflammatory marker called Neu5Gc that can worsen inflammation. Processed meats, such as bacon, sausage, and deli meats, are often high in sodium and preservatives, further contributing to inflammation. Reducing or eliminating these from the diet may lead to symptom improvement for some individuals.
Gluten and Starch
For some people with AS, particularly those with gut issues, grains containing gluten (wheat, barley, rye) may trigger inflammation. Given the known link between AS and inflammatory bowel diseases like Crohn's disease, it is theorized that a gluten-free or low-starch diet could be beneficial for a subgroup of patients. A low-starch diet limits starches that may feed certain gut bacteria (like Klebsiella) which have been hypothesized to contribute to AS inflammation.
Alcohol and Caffeine
Excessive alcohol consumption has several detrimental effects on individuals with AS. It can:
- Aggravate inflammation.
- Decrease nutrient absorption.
- Interact negatively with AS medications, especially NSAIDs.
- Weaken bones and increase the risk of osteoporosis, a common complication of AS.
Some people also find that caffeine can be a trigger, particularly in caffeinated beverages like coffee and soda.
Nightshade Vegetables and Dairy
Certain foods are individual triggers. Nightshade vegetables (tomatoes, potatoes, peppers, eggplant) are a common source of anecdotal reports, though scientific evidence for a link with AS flares is lacking. Similarly, some people with AS report that dairy products worsen their inflammation, though there is no consensus on this. The best way to identify these personal triggers is to eliminate them temporarily and observe any changes in symptoms.
Comparison of Pro-Inflammatory vs. Anti-Inflammatory Foods
| Category | Pro-Inflammatory (Foods to Limit) | Anti-Inflammatory (Foods to Favor) | 
|---|---|---|
| Carbohydrates | Refined grains (white bread, pasta), added sugars, processed snacks, high-starch foods (potatoes) | Whole grains (quinoa, brown rice, oats), fruits, non-starchy vegetables, legumes | 
| Fats | Saturated fats (red meat, full-fat dairy), trans fats (fried foods, margarine), excess omega-6 oils | Omega-3 rich foods (fatty fish like salmon, flaxseed, walnuts), olive oil, avocados | 
| Protein | Red meat (beef, pork), processed meats (bacon, sausage) | Fatty fish, lean poultry, legumes, nuts, seeds | 
| Drinks | Sugary drinks, excessive alcohol, caffeine | Water, herbal teas | 
| Other | Highly processed foods, artificial sweeteners, high-sodium foods | Fresh herbs and spices (turmeric, ginger, garlic), colorful fruits and vegetables | 
How to Identify Your Personal Triggers
Since dietary triggers can vary between individuals, keeping a food and symptom diary is highly recommended. This practice involves documenting your meals and any subsequent symptoms (e.g., pain, stiffness, fatigue). An elimination diet, conducted under the supervision of a healthcare provider or registered dietitian, can also help pinpoint specific food sensitivities. Remember that any dietary change should support, not replace, standard medical treatment for AS.
Conclusion
While diet alone is not a cure for ankylosing spondylitis, what you eat can significantly impact your inflammation levels and overall well-being. By understanding what foods flare up ankylosing spondylitis, such as processed sugars, unhealthy fats, and red meat, and opting for a diet rich in anti-inflammatory whole foods, individuals can better manage their symptoms. Working closely with a healthcare professional is crucial to develop a personalized nutrition plan that complements medical treatment and improves quality of life. The Spondylitis Association of America offers valuable resources on managing AS with diet.