Skip to content

What bacteria is used as a probiotic? An essential guide

4 min read

An estimated 4 million U.S. adults reported using probiotics or prebiotics in 2012, a number that has likely grown significantly since. For those seeking to support digestive balance, it's important to understand what bacteria is used as a probiotic and why specific strains matter for targeted health benefits.

Quick Summary

Diverse microorganisms, most commonly from the Lactobacillus and Bifidobacterium families, are cultivated for probiotic products. Different species and strains offer unique health benefits based on their function in the body. Other beneficial microbes like Bacillus and yeasts such as Saccharomyces boulardii are also utilized.

Key Points

  • Lactobacillus and Bifidobacterium: These are the two most common and well-researched bacterial families used as probiotics, found in fermented foods and supplements.

  • Strain Specificity is Key: The health benefits of a probiotic depend on the specific strain (e.g., L. rhamnosus GG), not just the bacterial genus.

  • Bacillus for Stability: Spore-forming Bacillus bacteria are highly resilient, able to survive stomach acid and heat, making them ideal for certain applications and products.

  • Yeast Probiotics: Saccharomyces boulardii is a beneficial yeast used as a probiotic, particularly effective for digestive issues like antibiotic-associated diarrhea.

  • Found in Food and Supplements: Probiotic bacteria are present in fermented foods like yogurt, kefir, and sauerkraut, as well as dietary supplements, each offering different concentrations and strains.

  • Diverse Roles: Probiotics work by producing lactic acid, fermenting fiber into short-chain fatty acids, competing with pathogens, and modulating the immune system.

In This Article

Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. The vast world of probiotics includes many different types of bacteria, each with distinct functions and effects on the human body. Understanding the various bacterial families and specific strains can help consumers make informed choices for their health needs.

Common Probiotic Bacteria Families

Lactobacillus

This is perhaps the most famous and widely used group of probiotic bacteria, commonly found in fermented foods like yogurt and kimchi. Members of this genus are lactic acid bacteria, meaning they ferment sugars into lactic acid. This creates an acidic environment in the gut that can be inhospitable to many pathogenic bacteria. A recent revision of bacterial taxonomy split this large genus into 25 smaller genera, though the name is still frequently used.

Common Lactobacillus species used as probiotics include:

  • Lactobacillus acidophilus: Often found in yogurt and dairy, this strain is well-known for its role in digestion and promoting a healthy intestinal environment.
  • Lacticaseibacillus rhamnosus (formerly Lactobacillus rhamnosus): The famous strain L. rhamnosus GG (LGG) is a well-researched strain known for its ability to survive gastric transit and support the gut lining, particularly during antibiotic use.
  • Lactiplantibacillus plantarum (formerly Lactobacillus plantarum): Found in fermented foods like sauerkraut and kimchi, certain strains are studied for their potential to support digestive comfort and cardiovascular health.
  • Lacticaseibacillus casei (formerly Lactobacillus casei): Used in cheese and yogurt, specific strains like L. casei Shirota are known for aiding in digestive regularity.

Bifidobacterium

Another major group of beneficial bacteria, Bifidobacteria are among the first microbes to colonize the human gut, especially in breastfed infants. They are specialized at fermenting dietary fibers and complex carbohydrates that humans cannot digest alone, producing beneficial compounds called short-chain fatty acids (SCFAs).

Common Bifidobacterium species include:

  • Bifidobacterium lactis: Found in dairy products and supplements, strains of B. lactis have been shown to support digestive regularity, enhance immune function, and help the microbiome recover after antibiotic use.
  • Bifidobacterium longum: This species is a key fermenter of dietary fiber and has been researched for its ability to support psychological health via the gut-brain axis, as well as aid in digestive regularity.
  • Bifidobacterium bifidum: A resident of the intestines, B. bifidum produces lactic and acetic acid and can help with digestive and respiratory issues.

Bacillus

Unlike Lactobacillus and Bifidobacterium, Bacillus species are spore-forming bacteria, which makes them highly resistant to harsh conditions like high temperatures, stomach acid, and bile. This resilience ensures that they can survive manufacturing and transit through the digestive system to exert their effects.

Common Bacillus species include:

  • Bacillus subtilis: This soil-dwelling bacterium is naturally found in the human gut and has been studied for its ability to produce enzymes, improve gut flora, and support immune responses. It is used in the production of the Japanese food nattō.
  • Bacillus coagulans: This is a highly stable, spore-forming probiotic often used to manage diarrhea and promote digestive health.

Streptococcus

Certain strains of Streptococcus are considered beneficial and are used in probiotic products and fermented foods. Notably, Streptococcus thermophilus is a thermophilic (heat-loving) bacterium used as a starter culture alongside Lactobacillus delbrueckii subsp. bulgaricus to make yogurt. It is recognized as 'Generally Recognized as Safe' (GRAS) by the FDA.

Other Beneficial Microbes

Saccharomyces boulardii (Yeast)

While not a bacterium, this beneficial yeast is often included in probiotic formulations. It is particularly known for its ability to help restore gut health during episodes of diarrhea, including that caused by antibiotics. As a yeast, it is not affected by antibacterial antibiotics, making it an ideal choice for this purpose.

Probiotic Bacteria Comparison Table

Bacteria Family Common Species/Strains Primary Role & Benefits Common Food Sources
Lactobacillus L. acidophilus, L. rhamnosus GG, L. plantarum Produces lactic acid, aids digestion, supports gut lining, enhances immunity Yogurt, kefir, fermented foods, supplements
Bifidobacterium B. lactis, B. longum, B. bifidum Ferments fiber into SCFAs, supports gut-brain axis, promotes regularity Yogurt, kefir, fermented milk, supplements
Bacillus B. subtilis, B. coagulans Highly stable spore-former, produces enzymes, supports immunity Fermented soy (nattō), supplements
Streptococcus S. thermophilus Ferments lactose, used in yogurt, aids digestion Yogurt, other fermented dairy
Saccharomyces (Yeast) S. boulardii Restores gut health, effective during antibiotic-associated diarrhea Supplements, kefir

The Importance of Strain Specificity

As highlighted in the table, the benefits of a probiotic are highly specific to the individual strain, not just the genus. For example, one strain of Lactobacillus might excel at improving digestive regularity, while another might be more effective at supporting skin health. Reputable probiotic supplements will list the full, specific strain name (e.g., L. rhamnosus GG) on the label, which indicates the product has been studied for its claimed benefits. For instance, a pharmacist might recommend a yeast strain like Saccharomyces boulardii for antibiotic-associated diarrhea because antibiotics won't kill it, whereas a bacterial strain may be less effective when taken concurrently. Conversely, if the goal is to repopulate the bacterial flora after a course of antibiotics, specific Bifidobacterium or Lactobacillus strains would be appropriate. Always verify that the strain listed is supported by research for your intended use.

Conclusion

The diverse and complex world of probiotic microorganisms offers a variety of potential health benefits, most notably dominated by the bacterial genera Lactobacillus and Bifidobacterium. Other key players include the highly stable, spore-forming Bacillus species and beneficial yeasts like Saccharomyces boulardii. The crucial takeaway for consumers is to look beyond the general genus and identify the specific strain, as this is where the clinically proven benefits lie. Whether seeking to improve digestion, support immune function, or aid recovery from illness, understanding which microbes are used as probiotics is the first step toward a healthier gut.

For more information on probiotics, visit the National Center for Complementary and Integrative Health: https://www.nccih.nih.gov/health/probiotics-usefulness-and-safety.

Frequently Asked Questions

The most common probiotic bacteria belong to the genera Lactobacillus and Bifidobacterium. These are frequently found in fermented foods like yogurt and kefir, as well as dietary supplements.

No, probiotic products contain different species and specific strains of bacteria or yeasts. The health benefits are highly dependent on the individual strain, so products are formulated differently to target specific health outcomes.

Yogurt is typically made with starter cultures of Lactobacillus bulgaricus and Streptococcus thermophilus. Other probiotic strains like Lactobacillus acidophilus or Bifidobacterium lactis may be added afterward.

Yes, many fermented foods like yogurt, kefir, sauerkraut, and kimchi contain live cultures. However, the types and quantities of microbes vary, and for specific health concerns, a targeted supplement might be more effective.

Yes, they differ in location and function. Lactobacillus can reside throughout the digestive tract, producing lactic acid. Bifidobacterium is more concentrated in the large intestine, specializing in fermenting dietary fiber.

Some studies suggest taking a probiotic containing the yeast Saccharomyces boulardii with antibiotics, as it will not be killed by the medication. Other strains like Lactobacillus rhamnosus GG have also been shown to be effective.

Not necessarily better, but different. Spore-forming bacteria from the Bacillus genus are exceptionally stable, surviving heat and stomach acid to reach the intestines intact. This makes them ideal for certain supplement formats.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.