What Does Manuka Honey Do to Your Stomach? A Comprehensive Guide

October 5, 2025 •

4 min read

According to numerous studies, Manuka honey contains unique antibacterial and anti-inflammatory properties due to its high Methylglyoxal (MGO) content, setting it apart from regular honey. So, what does Manuka honey do to your stomach, and can it truly support your digestive health effectively?

Quick Summary

Manuka honey, rich in antibacterial MGO and antioxidants, may support stomach health by inhibiting harmful bacteria like H. pylori and soothing gut inflammation. Its prebiotic qualities can also help balance the gut microbiome, potentially easing issues like bloating, indigestion, and acid reflux.

Key Points

Fights Harmful Bacteria: Manuka honey's high MGO content can inhibit problematic gut pathogens like H. pylori and C. difficile.
Reduces Inflammation: The potent anti-inflammatory and antioxidant properties help soothe and calm the stomach lining, benefiting conditions like gastritis and IBD.
Balances Gut Flora: Acting as a prebiotic, it nourishes beneficial bacteria in the gut, promoting a healthier and more balanced microbiome.
Provides a Protective Coating: Its viscous texture can create a protective barrier, which helps soothe symptoms of acid reflux and GERD.
Requires Specific Grading: For therapeutic effects, especially for stomach issues, a higher MGO or UMF rating (e.g., UMF 20+) is generally recommended.
Can Exacerbate IBS: Individuals with a sensitivity to FODMAPs, particularly fructose, should be cautious as honey might worsen gas, bloating, and diarrhea.
Promotes Ulcer Healing: Manuka honey's antioxidant and anti-inflammatory actions have been shown to help heal stomach ulcers in animal studies.

How Manuka Honey Benefits Your Digestive System

Manuka honey's potential benefits for stomach health are largely attributed to its unique bioactive compounds, particularly Methylglyoxal (MGO). Unlike regular honey, Manuka honey has a potent and stable antibacterial effect that can target harmful pathogens in the gut, while also working to reduce inflammation and support a balanced gut flora. This combination of effects is what makes it a popular natural remedy for various gastrointestinal issues.

Combating Harmful Bacteria

One of the most researched benefits of Manuka honey is its ability to fight against specific harmful bacteria in the stomach. High concentrations of MGO have been shown to inhibit the growth of bacteria like Helicobacter pylori and Clostridium difficile. H. pylori is a common cause of stomach ulcers and gastritis, and Manuka honey's antimicrobial action can help manage these infections. In some animal studies, Manuka honey has demonstrated a significant ability to heal chronic ulcers. For cases involving severe food poisoning or diarrhea, such as those caused by C. difficile, Manuka honey's strong antibacterial effects may also help.

Soothing Inflammation

Inflammation in the digestive tract is a key factor in conditions like gastritis, Irritable Bowel Syndrome (IBS), and Inflammatory Bowel Disease (IBD). Manuka honey possesses potent anti-inflammatory properties that can help soothe and calm the lining of the stomach and intestines. A 2017 study found that Manuka honey effectively reduced gastric inflammation and oxidative stress in animal models, promoting faster ulcer healing. Its soothing effect can also create a protective barrier, which is especially helpful for those suffering from acid reflux or GERD, by protecting the stomach and esophageal lining from further acid damage.

Promoting a Healthy Gut Microbiome

Beyond just killing harmful bacteria, Manuka honey also acts as a prebiotic, which means it helps feed the beneficial bacteria in your gut. It contains fructo-oligosaccharides (FOS), which nourish good microbes like Lactobacillus and Bidifobacterium. A healthy and balanced gut microbiome is essential for proper digestion, a strong immune system, and overall well-being. By promoting a more favorable balance of gut flora, Manuka honey can assist with issues like bloating, constipation, and overall digestive function.

Manuka Honey vs. Regular Honey for Stomach Health

While all natural honey has some level of antibacterial and soothing properties, Manuka honey's effects are generally considered more potent due to its high MGO content. This table highlights the key differences when considering their impact on your stomach.


Feature	Manuka Honey	Regular Honey
Antibacterial Power	High and stable due to MGO; effective against specific pathogens.	Lower and less stable, primarily from hydrogen peroxide; less potent.
Prebiotic Effect	Proven prebiotic activity due to FOS, promoting good gut bacteria.	Some prebiotic activity, but less consistently documented or potent.
Anti-Inflammatory	Rich in polyphenols and antioxidants that actively reduce gut inflammation.	Contains some antioxidants, but generally has a lower anti-inflammatory effect.
Effect on Reflux	Can provide a soothing, protective coating for the esophagus and stomach.	Offers some relief, but the effect may be less targeted and less potent.
Active Compound	Methylglyoxal (MGO) is the primary active compound.	Primarily hydrogen peroxide, which is less stable and potent.

How to Use Manuka Honey for Stomach Issues

For optimal stomach benefits, it's recommended to take Manuka honey consistently. A common method is to consume one to two teaspoons directly, either in the morning on an empty stomach or before meals. You can also mix it with warm water (not hot, to preserve its benefits), herbal tea, or stir it into yogurt. Consistency is key to allowing its properties to take effect over several weeks. For specific issues, higher MGO or UMF ratings may be recommended for stronger therapeutic action, but it's important to consult a healthcare provider for personalized advice.

What to Look for: MGO and UMF Ratings

The strength of Manuka honey's antimicrobial properties is often indicated by its MGO (Methylglyoxal) or UMF (Unique Manuka Factor) rating. Higher numbers signify a greater concentration of these beneficial compounds. For stomach problems, especially those linked to bacterial issues, experts often recommend a higher-grade Manuka honey, such as UMF™ 20+ or MGO 829+. These higher grades are thought to offer stronger therapeutic benefits, while lower-grade versions are suitable for general wellness and maintenance. Always look for certification on the label to ensure authenticity.

Potential Side Effects and Considerations

While generally safe for most people, there are some considerations when using Manuka honey for stomach health. Individuals with diabetes or high blood sugar should consume honey in moderation due to its natural sugar content. Those with IBS, particularly if sensitive to FODMAPs (fermentable carbohydrates), might find that honey worsens their symptoms like gas and bloating. In some animal studies, isolated MGO worsened IBS symptoms, though this was not with whole honey. A low FODMAP elimination diet can help determine personal tolerance. As with any new treatment, it is always wise to consult a healthcare provider before starting, especially if you have pre-existing medical conditions or are on other medications.

Conclusion

Manuka honey offers a multi-pronged approach to supporting stomach health, combining potent antibacterial, anti-inflammatory, and prebiotic properties. By helping to combat harmful bacteria like H. pylori, soothing inflammation in the digestive lining, and fostering a balanced gut microbiome, it can be a valuable addition to a wellness routine. Its effectiveness is directly related to its MGO or UMF rating, with higher grades offering more targeted therapeutic benefits. While not a cure-all, and requiring consistency for best results, incorporating Manuka honey can help many people manage digestive discomfort and promote overall gut health. Remember to always seek professional medical advice for persistent or serious digestive issues. For more details on clinical studies, you can refer to authoritative sources like the National Institutes of Health.

Frequently Asked Questions

For digestive issues, you can take 1 to 2 teaspoons of Manuka honey, either by itself or mixed with warm water, on an empty stomach in the morning or before meals. Taking it consistently is important for potential therapeutic benefits.

Yes, Manuka honey may help with acid reflux and GERD. Its thick, viscous texture can coat the esophagus and stomach lining, creating a protective barrier against stomach acid. Additionally, its anti-inflammatory properties can help calm irritation.

Research indicates that the high concentration of Methylglyoxal (MGO) in Manuka honey is effective in inhibiting the growth of H. pylori, the bacteria that can cause stomach ulcers and gastritis.

For targeted therapeutic use, especially for stomach infections or ulcers, a higher MGO rating is recommended. Look for Manuka honey with a UMF 20+ (MGO 829+) or higher for stronger antibacterial and anti-inflammatory effects.

While generally safe, some individuals with IBS may experience worsened symptoms like gas, bloating, or diarrhea due to honey's fructose content, as it is a high-FODMAP food. People with bee allergies or diabetes should also exercise caution.

Manuka honey is distinct due to its high, stable MGO content, which gives it more potent and specific antibacterial and anti-inflammatory properties compared to the less stable effects of regular honey. It is also a more reliable prebiotic for gut health.

Yes, Manuka honey can help reduce bloating. Its prebiotic properties encourage the growth of beneficial gut bacteria, which improves overall digestion and can reduce the gas production that causes bloating.

The time frame can vary depending on the individual and the severity of the issue. Consistent use of a therapeutic-grade Manuka honey over several weeks (e.g., 4-6 weeks) is often recommended to observe noticeable improvements in digestive symptoms.