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What is the benefit of Lactobacillus salivarius?

4 min read

As of April 2020, Lactobacillus salivarius was reclassified as Ligilactobacillus salivarius, a probiotic microorganism celebrated for its diverse health-promoting properties. This beneficial bacterium, naturally present in the human mouth and gut, is particularly noted for its powerful antimicrobial actions and ability to support a healthy microbial balance.

Quick Summary

This probiotic strain, found in the mouth and gut, helps maintain a healthy microbial balance by producing acids and antimicrobial substances. It supports oral hygiene, improves gut health, and modulates the immune system to reduce inflammation in various body systems.

Key Points

  • Oral Health Improvement: Lactobacillus salivarius reduces the risk of dental caries by inhibiting Streptococcus mutans and lessens gum inflammation associated with periodontitis.

  • Antimicrobial Action: The probiotic produces bacteriocins and organic acids that suppress the growth of harmful bacteria, including H. pylori, E. coli, and pathogens causing bad breath.

  • Immune System Modulation: By interacting with the gut-associated immune system, certain strains can promote anti-inflammatory responses and increase overall immune function.

  • Support for Skin Health: Through the gut-skin axis, L. salivarius helps alleviate symptoms of skin conditions like atopic dermatitis and acne by reducing systemic inflammation.

  • Enhanced Digestive Comfort: It contributes to a balanced gut microbiome, supports nutrient absorption, and can promote faster recovery from intestinal inflammation.

  • Strain-Specific Benefits: The therapeutic effects are often strain-dependent, meaning different strains are more effective for specific health issues, such as WB21 for oral health or TCI153 for skin hydration.

In This Article

Oral Health Benefits: From Fresh Breath to Dental Protection

Lactobacillus salivarius is a natural inhabitant of the human oral cavity and plays a critical role in maintaining a healthy oral microbiome. Its antimicrobial properties and production of organic acids make it a powerful ally against harmful oral pathogens.

How L. salivarius Supports Oral Hygiene

  • Combats bad breath (halitosis): Studies show that daily consumption of L. salivarius can help control oral malodor and reduce malodor-related factors by balancing the oral microbial environment.
  • Reduces dental caries risk: This probiotic has been shown to decrease levels of Streptococcus mutans, a primary pathogen associated with tooth decay. By producing organic acids and competing for adhesion sites, it makes the oral environment less hospitable for cavity-causing bacteria.
  • Supports periodontal health: Clinical trials have demonstrated that certain strains, like L. salivarius WB21, can lead to improvements in plaque control and gum inflammation, particularly in smokers. It helps inhibit the growth of periodontitis-causing bacteria like Porphyromonas gingivalis.

Gut Health and Immune System Modulation

Beyond the mouth, Lactobacillus salivarius is also found in the gastrointestinal tract, where it contributes to overall digestive wellness and supports immune function. The gut and the immune system are deeply intertwined, with the microbiome playing a key role in immune response regulation.

Gastrointestinal and Systemic Effects

  • Restores gut microbiome balance: L. salivarius helps crowd out undesirable microbes and promotes a favorable environment for beneficial bacteria. Its metabolic byproducts, such as short-chain fatty acids, support a healthy gut ecosystem.
  • Fights pathogenic bacteria: This probiotic produces bacteriocins, which are potent antimicrobial peptides that can target and inhibit a range of harmful bacteria, including Helicobacter pylori, E. coli, and Salmonella species.
  • Reduces inflammation: Specific strains, such as L. salivarius UCC118 and L. salivarius Ls-33, have demonstrated anti-inflammatory effects in animal models of colitis. This is often achieved through the upregulation of anti-inflammatory cytokines like interleukin-10 (IL-10).
  • Modulates systemic immunity: As much as 70% of the immune system resides in the gut. By positively influencing the gut microbiome, L. salivarius contributes to a more balanced and responsive immune system.

Benefits for Skin Health through the Gut-Skin Axis

The link between gut health and skin health, known as the gut-skin axis, means that modulating the gut microbiome can have a positive impact on skin conditions. L. salivarius has shown promise in this area by reducing inflammation and improving skin barrier function.

L. salivarius and Dermatological Support

  • Alleviates atopic dermatitis (eczema): Some studies have shown that supplementation with L. salivarius can significantly improve clinical symptoms in children and adults with moderate to severe atopic dermatitis by modulating the immune system and balancing gut flora.
  • Reduces acne and rosacea-related inflammation: By calming systemic inflammation and supporting a healthy gut, this probiotic can help reduce the frequency and severity of acne breakouts, along with the redness and irritation associated with rosacea.
  • Enhances skin hydration and elasticity: Research on the strain L. salivarius TCI153 revealed its ability to increase skin hydration, reduce transepidermal water loss (TEWL), and boost collagen and elastin production, contributing to firmer, more radiant skin.

L. salivarius Strains and Application Methods

The effects of L. salivarius can vary significantly between different strains, highlighting the importance of choosing a probiotic product with clinically researched strains. The method of delivery, whether through supplements or fermented foods, can also influence its effectiveness.

Comparison of Common L. salivarius Strains

Strain Primary Applications Noteworthy Properties Research Focus
UCC118 Gastrointestinal health, anti-inflammatory, pathogen inhibition Produces bacteriocin Abp-118 that inhibits Listeria. Anti-inflammatory effects in colitis models and pathogen defense.
WB21 Oral health, halitosis, dental caries, periodontitis Reduces S. mutans and periodontal pathogens. Clinical trials on plaque control and bad breath.
TCI153 Skin health, hydration, anti-aging Increases collagen, elastin, and EGF production. Dermatological benefits and the gut-skin axis.
AR809 Oral and pharyngeal health, immunity modulation Antimicrobial against Staphylococcus aureus. Adhesion to pharyngeal cells and immune modulation.

Conclusion

In summary, the benefits of Lactobacillus salivarius are diverse and extend from the mouth to the gut and skin. Its ability to produce antimicrobial substances, modulate the immune response, and support a balanced microbiome makes it a valuable probiotic. While individual strains offer specific advantages, the overall evidence points to its potential for enhancing oral hygiene, promoting digestive comfort, and contributing to healthier skin. The growing body of research, particularly in clinical settings, continues to uncover new applications and deepen our understanding of this beneficial bacterium. Consistent intake, often through multi-strain supplements or fermented foods, appears to be the most effective way to harness its positive effects.

For more in-depth scientific reviews on the characteristics and applications of various Ligilactobacillus salivarius strains, visit the National Institutes of Health website.

Frequently Asked Questions

Lactobacillus salivarius is most effective for supporting oral health, including reducing bad breath and mitigating dental caries risk. It is also highly beneficial for modulating the gut microbiome and immune system, which can, in turn, positively affect skin conditions like eczema.

No, while belonging to the larger group of lactic acid bacteria, Lactobacillus salivarius is a distinct species with unique properties. Its benefits, including the specific bacteriocins and acids it produces, differ from other probiotics like L. reuteri or L. acidophilus.

For most healthy individuals, Lactobacillus salivarius is well-tolerated. Some people may experience temporary digestive side effects like mild bloating or gas as their system adjusts. Individuals with compromised immune systems or damaged heart valves should consult a healthcare provider before use.

By balancing the gut-skin axis, L. salivarius can reduce systemic inflammation that contributes to skin issues. Specific strains also boost skin hydration, elasticity, and barrier function, offering a benefit for conditions like atopic dermatitis.

Lactobacillus salivarius was reclassified in 2020 as Ligilactobacillus salivarius based on genomic sequencing. For practical purposes, they refer to the same probiotic species, though product labels may use either name.

Yes, Lactobacillus salivarius can be found in some fermented foods. However, commercial products like yogurt often contain specific starter cultures and may not include this species unless specifically listed. Probiotic supplements are a more reliable source for consistent, specific strains.

Yes, it is considered possibly safe for children of most ages, with some formulations designed for pediatric use. However, parents should consult a healthcare provider, especially for young or premature infants, before starting supplementation.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.